Clinical trials: Proximal Femur Fracture
Fracture of Proximal Femur
Effect of Dexmedetomidine and Bupivacaine for Paravertebral Block
Fracture femur is a common that results in severe pain. Many methods of regional and peripheral analgesia have been described to treat such pain.
- Trial name
- NCT02801188
- Testing
- Bupivacaine, Mixture of bupivacaine and dexmedetomidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Mansoura University
Intertrochanteric Fractures
Addition of Aerobic Training to Conventional Rehabilitation After Femur Fracture
The primary purpose of this study is to assess the feasibility of an arm cycle ergometer training in subjects with proximal femur fracture surgically treated.
- Trial name
- NCT04025866
- Testing
- Conventional rehabilitation, Aerobic exercise
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Femoral Fracture
Pericapsular Nerve Block in Proximal Femoral Fractures
Proximal femoral fractures commonly occur above 50 years and regional anesthesia could be a complement in the perioperative treatment of the patients.
- Trial name
- NCT05840458
- Testing
- PENG Block
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- Hospital Sirio-Libanes
Trochanteric Fractures
PFNA vs Dual Mobility in Treatment of Unstable Trochanteric Fractures
Proximal femoral nail [PFNA] versus dual mobility arthroplasty in treatment of unstable trochanteric fractures
- Trial name
- NCT05677191
- Testing
- Proximal Femoral Nail, Dual Mobility Arthroplasty
- Volunteers
- 40 people
- Sponsor
- Cairo University
Fractures
Feasibility And Safety Study Of rhBMP-2/CPM For Hip Fractures
The primary objective of this study is to assess the safety of administering rhBMP-2/CPM as an adjuvant to internal fixation in subjects with fractures of the proximal femur.
- Trial name
- NCT00384358
- Testing
- rhBMP-2/CPM, surgical intervention alone
- Where
- 30 sites in United States, Australia and 8 more
- Volunteers
- 108 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Reverse Oblique Intertrochanteric Fractures, Reverse Oblique Subtrochanteric Fractures
Proximal Femur Locking Compression Plates Versus Trochanteric Nails
The purpose of this study is to compare the abductor muscle strength measured with a dynamometer in patients with reverse oblique inter- or subtrochanteric fractures treated either with a proximal femur locking plate or a…
- Trial name
- NCT01128868
- Testing
- Proximal femur locking plate, Intertrochanteric nail
- Where
- 3 sites in Australia, Switzerland
- Volunteers
- 14 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Fractured Neck of Femur
Single Dose of Dexamethasone in Femur Fractures
Fracture neck of femur is a common cause of hospital admission in the elderly and requires operative fixation. Dexamethasone has the potential of inhibiting cortisol secretion.
- Trial name
- NCT01550146
- Testing
- Dexamethasone acetate
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Proximal Femur Fractures
Fascia Iliaca Compartment Block for Proximal-end Femur Fractures
Fracture femur is a common injury which is associated with excruciating pain. Positioning for neuraxial blocks is always challenging because even slight overriding of the fracture ends is intensely painful .It can causing major…
- Trial name
- NCT02696915
- Testing
- Bupivacaine, Ultrasound guided fascia iliaca compartment block, Intrathecal medications (bupivacaine (15 mg) in conjunction with fentanyl 20 micrograms)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Hip Surgery, Femoral Neck Fractures
Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery
Hip and proximal femur surgeries are commonly performed in elderly patients and require anesthetic techniques that provide adequate surgical anesthesia while minimizing the need for additional opioid administration.
- Trial name
- L-ESP-HIP Stud (NCT07427082)
- Testing
- Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4), Spinal Anesthesia (L4-L5)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gaziantep City Hospital
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Osteoporosis, Proximal Femur Fracture
In Vivo Hip Fracture Discrimination With Quantitative Computed Tomography (QCT)
Numerous geometric and bone mineral density (BMD) parameters can be derived from quantitative computed tomography (QCT) images of the proximal femur analyzed using dedicated software.
- Trial name
- FEMFRACT (NCT01035177)
- Where
- France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bony Weight Bearing Disorder
After Hip Fracture Nailing, Compare Early Weight Bearing as Tolerated (WBAT) Group With Weight Bearing Restriction(WBR)
Purpose: Proximal femur fracture is a major traumatic injury in elderly populations; however, practical postoperative weight-bearing protocols are lacking.
- Trial name
- NCT06329271
- Testing
- Early-Weight bearing
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder
Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study.
Patients with metastases to proximal femur, who are evaluated fr the risk of pathologic fracture in order to decide on preventive fixation vs follow-up constitute the study population. The patients will be randomized in two arms.
- Conditions
- Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder, Bone Metastases, Proximal Femoral Metaphyseal Abnormality
- Trial name
- ZYCTFEA (NCT03453905)
- Testing
- CTFEA, Conventional decision algorithm
- Volunteers
- 162 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Proximal Humeral Fractures
Hip-allograft In Proximal Humerus Fractures Versus Plate Implantation Alone: a Randomized Controlled Trial
Proximal humerus fractures (PHFs) are common osteoporotic fractures in adults and the elderly, leading to significant disability and reduced quality of life.
- Trial name
- HIPPI (NCT07538700)
- Testing
- Locking plate fixation with femoral allograft augmentation
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Tergooi Medical Center
Proximal Femoral Fractures
Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures
The goal of this clinical trial is to compare outcomes in the treatment of proximal femur fractures. The main question it aims to answer is whether the use of a double cephalic screw prevents nail failure (cut-out).
- Trial name
- NCT06293495
- Testing
- Gamma 3 Nail (Stryker), Chimaera Nail (Orthofix)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Puerta de Hierro University Hospital
Hip Fracture
Influence of Static Distal Locking of a Short Proximal Femoral Nail
Prospective, comparative, randomized, double-blind study to evaluate the outcomes of trochanteric nailing in unstable hip fractures with and without a distal interlocking screw.
- Trial name
- NCT06357312
- Testing
- hip trochanteric nail
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Elda University Hospital
Unstable Trochanteric Fractures
Proximal Femoral Nail Antirotation™ (PFNA) Versus Gamma Nail 3™ (Gamma3) for Intramedullary Nailing of Unstable Trochanteric Fractures
The purpose of this study is to compare rates of any fracture fixation complication and revision rates after intramedullary fixation of unstable trochanteric fractures between the Proximal Femoral Nail Antirotation™…
- Trial name
- PROGAINT-ES (NCT00736684)
- Testing
- Proximal Femoral Nail AntirotationTM (PFNA), Gamma Nail 3TM (Gamma3)
- Where
- 6 sites in Spain
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Intertrochanteric Fractures
Effectiveness of Using Closed-suction Drainage in Treating Proximal Femur Fracture With Cephalomedullary Nail
Introduction: The closed suction drainage system is widely used in proximal femur surgeries. Recently, the proximal femoral nail antirotation (PFNA) system was advocated for treating intertrochanteric fractures (ITFs) in the…
- Trial name
- NCT04229212
- Testing
- hemovac drain (Zimmer Biomet, Autotransfusion System [HAS], United State)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Hip Fractures, Closed Fracture of Hip
Proximal Femoral Nail Antirotation (PFNA) Versus PFNA Augmentation
The purpose of this study is to evaluate whether patients with trochanteric fractures being treated with a Proximal Femoral Nail Antirotation (PFNA) and augmentation can better be mobilized than patients without augmentation.
- Trial name
- NCT01473082
- Testing
- PFNA Augmentation (Synthes), PFNA (Synthes)
- Where
- 9 sites in Austria, Belgium and 4 more
- Volunteers
- 251 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation