Clinical trials: Prosthesis Failure
Osteoarthritis
The Press Fit Condylar (P.F.C.) Sigma Rotating Platform (RP) TC3 Revision Knee in Revision Knee Arthroplasty
The purpose of this study is to evaluate the long-term clinical and functional performance of the P.F.C. Sigma Rotating Platform TC3 knee system in revision knee surgery and to determine whether the implant design results in a…
- Trial name
- TC3 (NCT00733681)
- Testing
- PFC Sigma RP TC3 Revision knee system
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 181 people
- Sponsor
- DePuy International
Implant Complication, Implant Infection
Local Antibiotics for Breast Implants
The BREAST-AB Trial is a multi-center, randomized, double blind, placebo-controlled trial investigating the efficacy of local application of gentamicin, vancomycin and cefazolin in decreasing all-cause implant explantation after…
- Conditions
- Implant Complication, Implant Infection, Implant Site Infection, Implant Capsular Contracture
- Trial name
- BREAST-AB (NCT04731025)
- Testing
- Gentamicin, Cefazolin and Vancomycin
- Where
- 8 sites in Denmark
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Mikkel Herly
Capsular Contracture, Implant
Ultrasound Guided Treatment of Steroids for Capsular Contracture in Patients With Reconstructed/Augmented Breast
Ultrasound guided treatment of steroids for capsular contracture in patients with reconstructed/augmented breast
- Trial name
- NCT03171974
- Testing
- Dexamethasone, US
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Partial Edentulism, Disorder of Prostheses and Implants
Survival of Implant-Supported All-Ceramic Prostheses
The purpose of this research study is to identify reasons that cause an all-ceramic bridge to fracture which include the thickness of the bridge material, the type of bridge material and the bite force of the person.
- Conditions
- Partial Edentulism, Disorder of Prostheses and Implants, Dental Prosthesis Failure
- Trial name
- NCT01729858
- Testing
- Ceramic-Ceramic, Metal-Ceramic
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Florida
Prosthesis Durability
Accuracy of 3-dimensional Printed Implant Cast Versus Conventional Stone Cast for Edentulous Mandibular Arch
This study will be conducted to compare between accuracy of 3D printed implant cast produced from digital impression and conventional stone cast produced from conventional splinted open tray impression for edentulous mandibular…
- Trial name
- NCT06050187
- Testing
- implant casts fabrication
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostheses, Endosseous Dental Implant Failure
Pink Esthetic Score Around Immediate Implants Using PDDM as Jumping Gap Filling Material.
Will there be a difference in Pink Esthetic score and soft tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix compared with xenograft?
- Trial name
- NCT05952765
- Testing
- Immediate implant
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Survival, Prosthesis
Osteopontin in Metastatic Breast Cancer Patients
OPN plays an important role in various aspects of malignancy, particularly those involved in tissue invasion and metastasis, and OPN levels have been associated with aggressive¬ness in several cancer types, including breast…
- Trial name
- NCT04274504
- Testing
- Osteopontin
- Where
- Egypt
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Complication, Prosthesis Durability
SEBBIN Silicone Gel-filled Testicular Implants
This study is part of the clinical evaluation of SEBBIN silicone gel-filled testicular implants, included in the technical file of the device.
- Trial name
- NCT04968470
- Where
- 2 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Groupe SEBBIN
Dental Prosthesis Failure
Survival of Different Core Build-up Materials
The purpose of this study is to compare three different core build-up materials for dental use. The study hypothesis is that there is no differences in survival rate of the different core build-ups.
- Trial name
- NCT01449903
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Heidelberg University
Loosening, Prosthesis
Identification of Infections in Hip Arthroplasty Loosening.
Recent data showed that the rate of periprosthetic infections in patients undergoing a hip arthroplasty revision for aseptic loosening is higher than what can be ascertained with conventional methods.
- Trial name
- NCT04773054
- Testing
- Microbiological analysis of periprosthetic tissue, Histological analysis of periprosthetic tissue, Characterization of tissue microbiota
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Ortopedico Rizzoli
End-stage Renal Disease, Kidney Failure, Chronic
Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01744418
- Testing
- HAVG graft implantation
- Where
- 3 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Humacyte, Inc.
Edentulous Mouth, Dental Prosthesis Failure
Retrospective Clinical Evaluation of Nano-hybrid-composite Denture Teeth
This retrospective study investigates the longevity of dentures with SR Phonares II teeth after a wearing period of more than 10 years.
- Trial name
- NCT05599269
- Testing
- Examination of dentures with SR Phonares II teeth
- Where
- Liechtenstein
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Ivoclar Vivadent AG
Breast Implant-Associated Anaplastic Large Cell Lymphoma, Capsular Contracture, Implant
Breast-implant ASsocIated anaplastIc Large Cell Lymphoma and CApsular Contracture
BASILICA is a UK NIHR Biomedical Research Centre funded study recruiting patients at The Royal Marsden NHS Foundation Trust. The study aims to obtain blood and tissue samples from patients with breast implant-associated…
- Conditions
- Breast Implant-Associated Anaplastic Large Cell Lymphoma, Capsular Contracture, Implant, Breast Implant; Complications
- Trial name
- BASILICA (NCT05017337)
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Prosthesis Survival
Single Tooth Implant-supported Fixed Prosthetic Rehabilitation Using PEEK.
The goal of this study is to evaluate the outcome of a Poly-ether-ether-ketone - used in single teeth implant-supported rehabilitations after one year of follow-up.
- Trial name
- PEEKPilotST (NCT05589532)
- Testing
- Prosthetic single-tooth prosthesis using PEEK
- Where
- Portugal
- Volunteers
- 9 people
- Sponsor
- Malo Clinic
Gingival Bleeding, Prosthesis Failure, Dental
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
This study aims to compare the horizontal gingival displacement by using a retraction cord and aluminum chloride gel, and also to determine the time taken for placement and hemorrhage after the procedure by using a retraction…
- Conditions
- Gingival Bleeding, Prosthesis Failure, Dental, Tissue Injury
- Trial name
- NCT07255976
- Testing
- knitted cotton retraction cord, aluminum chloride gel
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Prosthesis Durability
Effect of Geometric Modifications of Implant Scan Bodies
The aim of this clinical study will be the effect of geometric modifications of implant scan bodies compared to conventional transfer techniques on passivity of all on four mandibular restorations
- Trial name
- NCT06040385
- Testing
- Implant supported hybrid prosthesis
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dysplasia; Hip, Prosthesis Survival
Long-term Outcomes of Conical Tapered Stems in Cementless Total Hip Arthroplasty Due to Congenital Hip Pathologies
A retrospective consecutive population of patients treated with conical tapered stems in cementless total hip arthroplasty for osteoarthritis due to congenital hip pathologies will be selected.
- Trial name
- RetroCone (NCT04748458)
- Testing
- Conical tapered stem
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Replacement, Heart Failure
Metal-on-metal Hip Prostheses: Do They Have Systemic Effects?
This study aims to determine whether subjects who underwent large-diameter metal-on-metal hip arthroplasty are more likely to have developed heart failure or other conditions as compared to subjects with conventional hip…
- Trial name
- HipLink (NCT02382835)
- Where
- United Kingdom
- Volunteers
- 800,000 people
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Osteoarthritis, Hip, Hip Osteoarthritis
Clinical and Functional Outcome of the MobileLink Acetabular Cup System in the Short-, Mid-, and Longterm Follow-up
The implantation of artificial hip joints is one of the most frequently performed surgeries. Normally, patients are very satisfied with the results. The MobileLink hip prosthesis system is a CE marked medical device.
- Conditions
- Osteoarthritis, Hip, Hip Osteoarthritis, Prosthesis Survival, Prosthesis Failure
- Trial name
- NCT04688593
- Testing
- MobileLink
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 520 people
- Sponsor
- Waldemar Link GmbH & Co. KG