Clinical trials: Prosthesis
Transfemoral Amputation
Sub-Ischial Socket for Transfemoral Amputation and Lower Mobility
The objective of this trial is to assess use and benefits of the subischial socket for persons with transfemoral amputation and lower mobility levels.
- Trial name
- NCT05662982
- Testing
- Northwestern University Flexible Subischial Suction Socket (NU-FlexSIS)
- Where
- 3 sites in United States
- Volunteers
- 84 people
- Sponsor
- University of Washington
Cost Effectiveness
Cost-Effectiveness Study on Establishing a Warfarin Counseling Clinic for Egyptian Patients With Mitral Valve Prostheses
The outcome of poor adherence to medications can be life threatening with certain drugs like warfarin. For each 10% increase in non-adherence to warfarin, there was a 14% increase in the risk of under-anticoagulation with…
- Trial name
- NCT04409613
- Testing
- Education and counseling
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Ain Shams University
Complications Due to Internal Joint Prosthesis, Thumb Osteoarthritis
Study of the Touch® Trapezo-metacarpal Prosthesis
Prospective observational study of implanted patients with a new orthopaedic implant: the Touch trapezo-metacarpal prosthesis
- Trial name
- NCT03611023
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Groupe Concepteur Touch
Prosthesis User, Prosthesis
Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis
This study is focused on optimizing methods for controlling upper-limb myoelectric prosthetic arms. If you are enrolled in this study you would be expected to visit one of the research sites for approximately 5 in-lab visits…
- Conditions
- Prosthesis User, Prosthesis, Prosthetic, Upper Limb Amputation
- Trial name
- NCT07850544
- Testing
- Condition A: Electrode Configuration, Condition B: Electrode Configuration, Condition C: Electrode Configuration
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Edentulism Complete, Dental Implant
Quality of Life, Nutritional Status and Aesthetics in Patients Rehabilitated With FP1 Full-Arch Reconstructions
The World Health Organization defines quality of life as "a state of physical, mental, and social well-being"; therefore, it is important to consider the patient holistically, taking into account social function and the ability…
- Trial name
- NCT07892014
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Turin, Italy
Temporomandibular Disorders (TMD), Temporomandibular Joint Ankylosis
Virtual Planning of Total Temporomandibular Joint Replacement
A total TMJ replacement surgery is currently planned based on the X-ray appearance of the facial X-ray. It is now possible to use either an individually designed TMJ prosthesis or a prosthesis with a standard appearance.
- Trial name
- NCT07373184
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University Hospital
Amputees, Prosthesis User
Effects of Pin and Vacuum Assisted Suspension Systems
This study was performed to determine the presence of any difference between Pin Suspension (PS) and Active Vacuum Suspension (AVS) on walking capacity, functional mobility, weight bearing in the prosthetic side, prosthetic…
- Conditions
- Amputees, Prosthesis User, Artificial Limbs
- Trial name
- NCT04155762
- Testing
- Pin Suspension System (a prosthetic suspension system), Vacuum-Assisted Suspension System (a prosthetic suspension system)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Baskent University
Tooth Loss and Rehabilitation With Telescopic Crown Prostheses
Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis
This study aims to compare the clinical and patient satisfaction outcomes of rigid versus non-rigid digitally fabricated telescopic double crown prostheses supported by teeth and implants.
- Trial name
- NCT07682623
- Testing
- Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Knee Osteoarthritis, Knee Disease
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
Hip arthroplasty surgery is frequently performed on elderly patients in the community and it is associated with long-term postoperative hospital stays and high mortality.
- Conditions
- Knee Osteoarthritis, Knee Disease, Knee Arthritis
- Trial name
- NCT05621161
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Cardiac Surgical Procedures, Heart Valve Prosthesis Implantation
Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients
There is evidence on the role of the phosphotransfer system in the energy metabolism of the heart, with altered energetics playing an important role in the mechanisms of heart failure.
- Trial name
- PRISE (NCT02757443)
- Testing
- Phosphocreatine sodium tetrahydrate after anaesthesia induction, 5% Glucose after anaesthesia induction, Phosphocreatine sodium tetrahydrate added to cardioplegia
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Mechanical Heart Valve Prosthesis
Noise Associated With a Mechanical Heart Valve Prosthesis: Does the Memory of Preoperative Information Have an Influence on Postoperative Quality of Life?
As part of the follow-up in the Day Hospital in the national reference center for Marfan syndrome and related disorders, each consultant benefits from a psychological interview.
- Trial name
- QUALICLIC (NCT07304115)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Hip
Efficacy of a New Resurfacing Hip Prosthesis
The purpose of this study is to compare the articular surface replacement (ASR) prosthesis placed by the conventional positioning method and the ASR prosthesis placed by 'computer assisted surgery' (CAS) in variation between pre…
- Trial name
- NCT00391937
- Testing
- Articular Surface Replacement (ASR) hip prosthesis
- Where
- 6 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Erasmus Medical Center
Candida Infection
One-stage Exchange in Candida Periprosthetic Infection a Suitable Way to go
Accounting for only 0.7% to 3% of joint prosthesis infections, yeast infections are considered particularly difficult to treat. They are primarily caused by Candida yeasts, representing over 90% of cases.
- Trial name
- CPCI (NCT07303101)
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Strasbourg, France
Knee Osteoarthritis
Effect of Noise Control During Total Knee Arthroplasty
Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress.
- Trial name
- NCT05714267
- Testing
- Active noise cancelling, Passive noice cancelling, Active noise cancelling with music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Dental Crowns, Dental Prosthesis
Zirconia and Metal-based Single Crown Posterior Restorations.
The objective of this study was to compare the 5-year survival and clinical behavior of single posterior ceramic crowns made with pressable ceramic on zirconia or on a metal framework.
- Conditions
- Dental Crowns, Dental Prosthesis, Prosthodontics
- Trial name
- NCT02758457
- Testing
- dental crowns
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Bologna
Gait Disorder, Sensorimotor
Pilot Study for Patient-cooperative Control Strategies for Actuated Transfemoral Prostheses
This pilot study investigates the feasibility of novel control strategies for actuated transfemoral prostheses. Several parameters from gait analysis (including motion-capture and ground reaction force measurements) are analyzed.
- Trial name
- NCT02310841
- Testing
- ANGELAA
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Swiss Federal Institute of Technology
Edentulous Jaw
Time-dependent Change in the Retention Force of the Implant Overdenture
This descriptive longitudinal study aimed to investigate the retention force of implant-supported overdentures applied to edentulous individuals at Marmara University Faculty of Dentistry, examine the retention force and its…
- Trial name
- NCT05675566
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Lower Limb Amputation
Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees
Following lower-limb amputation, the loss of somatosensory information from the missing limb renders walking less automatic, more cognitively demanding, and often asymmetric, which can lead to secondary pathologies.
- Trial name
- PhantomWalk (NCT07191795)
- Testing
- Gait analysis, Mapping of referred sensations., Exploration of the areas of the brain activated during referred sensations
- Where
- France
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Amputation, Amputation, Traumatic
Evaluation of Dexterous Terminal Device
Liberating Technologies, Inc. (LTI) has developed Pointdexter, a dexterous prosthetic fingertip that is integrated into a commercial prosthetic hand and allows for an additional fine grasp.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper
- Trial name
- NCT05840601
- Testing
- Pointdexter, Comparator
- Sponsor
- Liberating Technologies, Inc.
Amputation of Upper Limb, Agenesis of Upper Limb
Using Sensorimotor Reorganization Following Upper Limb Amputation to Improve Prosthetic Control
Amputation of an upper limb results in a disruption of the sensorimotor loop and a reorganization of the nervous system, leading to the emergence of a phantom limb and the adaptation of compensatory motor strategies.
- Trial name
- REINVENT (NCT07666204)
- Testing
- Caracterisation, Mapping, Phantom sensations
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est