Clinical trials: Prostate Biopsy, active
PCA, Prostate Cancer
PSMA PET Combined With MRI for the Detection of PCa
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection…
- Conditions
- PCA, Prostate Cancer, Prostatic Neoplasm, PSMA PET
- Trial name
- BiPASS (NCT07052214)
- Testing
- 68Ga-PSMA-11
- Where
- 18 sites in United States, Australia
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Prostate Biopsy, Sedation Complication
Effect of Remimazolam on Hypoxemia and/or Hypotension in Prostate Biopsy
This study aims to investigate whether remimazolam, a novel benzodiazepine sedative, can reduce the composite incidence of hypotension and hypoxemia during prostate biopsy in elderly patients compared with propofol.
- Trial name
- NCT07854197
- Testing
- Using remimazolam for sedation during prostate biopsy, Administer 1.5mg/kg of propofol for sedation
- Volunteers
- 1,146 people
- Sponsor
- RenJi Hospital
Prostate Biopsy, Post Biopsy Bleeding
Routine Probe Compression After Transrectal Prostate Biopsy(RPCAB) to Reduce Bleeding and Infectious Complications
Hematuria (up to 50%) and rectal bleeding (up to 30%) are common complications following transrectal ultrasound-guided prostate biopsy. Although most cases are mild, some require additional intervention.
- Conditions
- Prostate Biopsy, Post Biopsy Bleeding, Transrectal Ultrasound-guided Prostate Biopsy
- Trial name
- RPCAB (NCT07550985)
- Testing
- Probe compression
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Veterans Health Service Medical Center, Seoul, Korea
Prostate Cancer (Adenocarcinoma), Prostate Biopsy
RegisterPROS - A Registry for Prostate Cancers
Prostate cancers are derived from epithelial cells in the prostate gland. Treatment options include surgery, medical (androgen signaling targeted and chemotherapy) and radiation therapy including radioligand therapy (RLT).
- Conditions
- Prostate Cancer (Adenocarcinoma), Prostate Biopsy, Prostatectomy, Radioligand
- Trial name
- RegisterPROS (NCT06872619)
- Testing
- PROSTest
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Wren Laboratories LLC
Prostate Cancer (Diagnosis), Prostate Biopsy
TENS During Transperineal Prostate Biopsy
Transperineal prostate biopsy is a safe and effective method of diagnosing prostate cancer. When performed under local anaesthesia in an outpatient setting, it can cause significant pain, particularly during the periprostatic…
- Conditions
- Prostate Cancer (Diagnosis), Prostate Biopsy, Pain, Procedural
- Trial name
- TENS 2 (NCT07578324)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk
PROSTATE CANCER, Prostate Biopsy
Multi-parametric Ultrasound Versus Multi-parametric MRI for Prostate Cancer Detection
The goal of this cohort study is to investigate multiparametric ultrasound versus multiparametric MRI for clinically significant prostate cancer detection in patients scheduled for initial biopsy.
- Trial name
- TRUSVSMPMRI (NCT06183905)
- Testing
- Prostate imaging, Prostate biopsy
- Where
- China
- Volunteers
- 635 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Prostate Biopsy
Use of a Virtual Reality Headset During Prostate Biopsy Under Local Anesthesia to Improve the Patient's Experience
This is a post-market clinical investigation evaluating the effect of immersive virtual reality (VR) as an adjunct to standard local anesthesia during transperineal prostate biopsy.
- Trial name
- NCT07701421
- Testing
- Standard Local Anesthesia, Immersive Virtual Reality (VR) Headset
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Prostate Biopsy
A Multicenter, Randomized Controlled Superiority Trial Comparing Robotic-Assisted Versus Expert Cognitive Fusion Prostate Biopsy in Obese Men
The trial aims to find out if using a robotic system to help perform prostate biopsies is better than having a highly experienced doctor perform the biopsy by hand in men with a high Body Mass Index (BMI).
- Trial name
- NCT07600216
- Testing
- Robotic-Assisted Fusion Biopsy, Expert Cognitive Fusion Biopsy
- Volunteers
- 570 people
- Sponsor
- Shanghai East Hospital
Infectious Complications Following Prostate Biopsy, Prostate Cancer
A Study Comparing Infectious Complications After Transperineal Prostate Biopsy With or Without Antibiotic Prophylaxis
Prostate biopsy performed through the perineal skin (the area between the testicles and the anus), known as a transperineal biopsy, is currently considered the standard procedure for diagnosing prostate tumors, having replaced…
- Trial name
- NCT07557901
- Testing
- No antibiotic prophylaxis for prostate biopsy, Antibiotic prophylaxis (fosfomycin-trometamol) for prostate biopsy.
- Where
- Slovakia
- Volunteers
- 300 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Prostate Cancer (Diagnosis), Bone Metastasis
Plasma Exosomal RNA Signature for Prostate Cancer Bone Metastasis
Brief Summary: This prospective, multicenter study aims to discover, develop, and validate a plasma exosomal RNA-based signature as a rule-out test for predicting bone metastasis in prostate cancer, using baseline treatment-naïve…
- Conditions
- Prostate Cancer (Diagnosis), Bone Metastasis, PSMA PET, Liquid Biopsy
- Trial name
- EXO-MET (NCT07553754)
- Where
- 9 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Prostate Biopsy
A Study of Optical Fusion Trans-Perineal Grid
The purpose of this research is to evaluate a new needle guide grid utilizing Clear Guide SCENERGY - MR with a grid embedded with VisiMARKER II to autoregister and target the prostate aiding in needle placement positioning.
- Trial name
- NCT05573048
- Testing
- Trans-Perineal Grid
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Urologic Diseases, Prostate Biopsy
VIrtual Reality Induced Pain and anxiEty Relief in Outpatient UROlogical Procedures
Though the efficacy of VRH is documented in various outpatient urological procedures and has provided promising preliminary information in prostate biopsy, its systematic use in urology remains poorly studied.
- Conditions
- Urologic Diseases, Prostate Biopsy, Flexible Cystoscopy, Circumcision
- Trial name
- NCT07338292
- Testing
- REALICA, Clinical Practice
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Prostate Cancer, Procedural Pain Relief
AcuTENS for Pain Relief During TRUS-Guided Prostate Biopsy
This study evaluates whether transcutaneous electrical nerve stimulation applied at specific acupuncture points (AcuTENS) can reduce pain and anxiety during transrectal ultrasound-guided prostate biopsy for participants suspected…
- Conditions
- Prostate Cancer, Procedural Pain Relief, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY, Transcutaneous Electrical Nerve Stimulation
- Trial name
- NCT07292337
- Testing
- Active AcuTENS
- Where
- Malaysia
- Volunteers
- 53 people
- Sponsor
- University of Malaya
Anxiety, Pain
The Effectiveness of Stress Ball in Managing Anxiety and Pain During Prostate Biopsy
This study aimed to determine the effectiveness of stress ball application in the management of anxiety and pain during prostate biopsy.
- Conditions
- Anxiety, Pain, Prostate Biopsy
- Trial name
- NCT07101172
- Testing
- stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hitit University
Prostate Cancer, Prostate Biopsy
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Prostate cancer is now the most common cancer in men in the Western world. In the United Kingdom (UK), there were over 52,000 new cases diagnosed in 2016-2018 and a lifetime risk of 1 in 8.
- Conditions
- Prostate Cancer, Prostate Biopsy, Genetic Counselling, Genetic Markers
- Trial name
- PROFILE (NCT02543905)
- Testing
- Prostate MRI and Biopsy
- Where
- United Kingdom
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Prostate Biopsy
Impact of Procedure Materials on Patient Anxiety, Depression, and Pain in Prostate Biopsy Consent
The gold standard for diagnosing prostate cancer is an ultrasound-guided prostate biopsy. Despite its low complication rates, the procedure can cause significant stress, discomfort and anxiety in patients.
- Trial name
- NCT06802783
- Testing
- Photo consent
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prostate Biopsy
Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia:
The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a…
- Trial name
- HYPNOSURG-VR (NCT06691438)
- Testing
- prostate biopsy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC