Clinical trials: Prospective
Aneurysmal Subarachnoid Haemorrhage
CytoSorb SAH Trial
In aSAH high levels of IL-6 (a pro-inflammatory cytokine) in the cerebrospinal fluid, as well as systemically have been linked to the severity grade and the occurrence of vasospasm and delayed cerebral ischemia caused by…
- Trial name
- NCT05259514
- Testing
- CytoSorb
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Emanuela Keller
Stevens-Johnson Syndrome, Kidney Failure, Chronic
HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction
Allopurinol-induced severe cutaneous adverse reaction (SCAR) is a rare but fatal condition. Previous reports have reported that HLA-B*5801 is an important genetic risk factor significantly associated with the development of…
- Trial name
- NCT03046914
- Testing
- HLA-B*5801 test
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Seoul National University Hospital
Covid19
COVID-19 IgG Antibodies in the Serum of Recovered Patients
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in China, in December 2019 and is now spreading worldwide and poses a great…
- Trial name
- NCT04470414
- Testing
- IgG antibodies immunoassay
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2
Glufast On Insulin Glargine Trial in Type 2 DM
We will evaluate the efficacy and safety of combination therapy of 10 mg mitiglinide or 0.2mg voglibose with insulin glargine for 16 weeks after single administration of insulin glargine for 4 weeks in type 2 diabetic patients…
- Trial name
- GLORIA (NCT00663884)
- Testing
- Mitiglinide, Voglibose
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- JW Pharmaceutical
Body Weight Changes, Rocuronium
Lean Body Weight-adjusted Rocuronium Dose and Intubation Conditions
In this study, researchers wiil administer rocuronium, based on either the lean body weight or the total body weight in patients with body mass index (BMI) of 18.5 to 34.9 and compared the duration of action of the drug and its…
- Conditions
- Body Weight Changes, Rocuronium, Intubation Conditions
- Trial name
- LBW (NCT05476952)
- Testing
- he patients who are administered rocuronium according to LBW were categorized as "LBW", and The group number for those administer according to TBW was categorized as "K".
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- DUYGU DEMİROZ
Acute Myocardial Infarction, Women Over 18 and Under 50 Years of Age
WAMIF : Young Women Presenting Acute Myocardial Infarction in France
MI in elderly women seems to share the same pathophysiology than in men, especially plaque rupture associated with conventional risk factors.
- Trial name
- WAMIF (NCT03073447)
- Testing
- Specific blood sample of women under 50 years with acute MI
- Where
- 29 sites in France
- Volunteers
- 324 people
- Sponsor
- French Cardiology Society
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Wrist Fractures
Early Functional Outcomes After Closed Reduction With Pinning Versus Open Reduction Internal Fixation of Wrist Fractures
The purpose of this study is to compare early return to function in patients treated with closed reduction percutaneous pinning and open reduction internal fixation in displaced fractures of the distal radius.
- Trial name
- NCT00828685
- Testing
- CRPP, ORIF
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Embryo Culture
A Prospective Study Comparing the Outcomes of Single Versus Group Culture in Preimplantation Genetic Testing Cycles
The aim of this study is to analyze whether there is difference in the effect of single embryo culture and group culture in preimplantation genetic screening (PGS) cycle, and provide reference for the feasibility of the clinical…
- Trial name
- NCT03464643
- Testing
- embryo culture
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases
Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT01507415
- Where
- 2 sites in United Kingdom
- Volunteers
- 226 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
ALS (Amyotrophic Lateral Sclerosis)
Amyotrophic Lateral Sclerosis Registry in Thailand
This is a prospective, observational, multicenter registry designed to collect comprehensive clinical, genetic, and outcome data from patients diagnosed with amyotrophic lateral sclerosis (ALS) across Thailand.
- Trial name
- Thai ALS Regis (NCT07175935)
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Sintilimab and Anlotinib in Combination With Chemotherapy
Sintilimab and Anlotinib Combined With Chemotherapy in Neoadjuvant Treatment of Resectable Esophageal Cancer
The study focused on patients with T2-4NxM0 resectable esophageal carcinoma. Neoadjuvant treatment involved administering anlotinib (10 mg orally, once a day, 2 weeks on and 1 week off) for anti-angiogenesis and sintilimab (200…
- Trial name
- NCT06015035
- Testing
- Sintilimab and anlotinib in combination with chemotherapy
- Where
- 2 sites in China
- Volunteers
- 17 people
- Sponsor
- Tang-Du Hospital
Stroke, Shoulder Injury
STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke
Background and Rationale: The most commonly seen disabilities in stroke patients are shoulder injuries such as shoulder pain, glenohumeral subluxation, spasticity of shoulder muscles, soft-tissue trauma, rotator cuff tears, and…
- Trial name
- STRIPS (NCT01062308)
- Where
- 2 sites in India
- Volunteers
- 162 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Wound, Wound Infection
Evaluating Surface Area Reduction Using MolecuLight Imaging Device
12-week single-blind, prospective, randomized, controlled, pilot clinical trial assessing The MolecuLight i:X Imaging Device in chronic wounds.
- Trial name
- NCT03181568
- Testing
- MolecuLight i:X™ Imaging Device, Wound care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Calver Pang
Central Venous Catheterization
Comparison of the Proximal Approach and Distal Approach of Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the proximal or distal approach of the axillary vein. The aim of our study is to compare the first puncture success rate and safety between the two approaches…
- Trial name
- NCT03395691
- Testing
- The distal approach, The proximal approach
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Shanghai Zhongshan Hospital
Locally Advanced Rectal Cancer
Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME: Prospective Phase II Trial
The investigators start this prospective study to evaluate the efficacy of laparoscopic total mesorectal excision after concurrent chemo-radiation therapy with hyperthermia in locally advanced rectal cancer.
- Trial name
- NEOTREAT (NCT02290574)
- Testing
- Hyperthermia with concurrent chemo-radiation therapy
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
Pregnant Women
Outpatient Induction of Labour Using a Double Balloon Transcervical Catheter in Low-risk Pregnant Women: a Two-centre Open Prospective Randomised Controlled Trial - OutCRIB
The aim goal of this study is to compare the duration of induction and labor between outpatient and inpatient care in low-risk pregnant women.
- Trial name
- OutCRIB (NCT07265518)
- Testing
- Outpatient, Inpatient
- Where
- 2 sites in France
- Volunteers
- 258 people
- Sponsor
- Nantes University Hospital
Neuroma, Phantom Limb Pain After Amputation
Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Neuroma, Phantom Limb Pain After Amputation, Stump Pain, Platelet-rich Plasma (PRP)
- Trial name
- PRP-NEUROMA (NCT07624890)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Local Anesthetic Injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Epilepsy
Epilepsy and Mood Regulation Disorder in Children
Epilepsy is a multifaceted disorder and a major public health problem. In addition to recurrent and unpredictable seizures, abnormalities in psychiatric status, cognition and social-adaptive behaviors are potential major sources…
- Trial name
- EPILETRE (NCT02568813)
- Testing
- Multiscore Depression Inventory for Children scale
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Heart Attack, NSTEMI
A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction
This is a double-blind, sham-controlled clinical study to evaluate the safety and feasibility of AMI MultiStem therapy in subjects who have had a heart attack (Non-ST elevation MI).
- Trial name
- MI-NSTEMI (NCT02277613)
- Testing
- AMI MultiStem cells
- Where
- 11 sites in United States
- Volunteers
- 34 people
- Sponsor
- Healios K.K.
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