Clinical trials: Propofol Pain Injection
Propofol Injection Pain in Children
Determining if the Buzzy® Personal Pain Relief Device Reduces Injection Pain of Propofol as Much as Intravenous Lidocaine in Children
Propofol is a drug commonly used for induction of general anesthesia in children as well as adults; however, propofol can cause pain on injection, possibly more frequently in children.
- Trial name
- NCT07770581
- Testing
- Buzzy device, Intravenous lidocaine
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Propofol Injection Pain
Arm Elevation for Prevention of Propofol Injection Pain
The purpose of this research is to determine whether a simple technique, temporarily raising the arm during the injection of propofol (a commonly used medication for anesthesia), can reduce the pain that some people experience…
- Trial name
- NCT07785674
- Testing
- Passive arm elevation, Normal saline, Lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Effect of Patient Awareness on Incidence and Severity of Propofol Injection Induced Pain
Effect Of Patient Awareness About Possibility Of Occurrence Of Pain During Propofol Injection On The Rate Of Incidence And Severity Of Pain During Injection .
Propofol is the most common intravenous (IV) anesthetic agent, used for anesthesia induction and maintenance during surgeries due to its rapid onset and short duration.
- Trial name
- No acronym (NCT05886972)
- Testing
- Awareness about propofol injection induced pain
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Anesthesia Induction, Propofol Pain Injection
Ondansetron Versus Lidocaine for Preventing Pain on Propofol Injection.
This is a prospective, single-center, randomized, double-blind controlled trial involving patients scheduled for elective surgery requiring general anesthesia with propofol induction.
- Trial name
- NCT07632144
- Testing
- Group C (Control), Ondansetron 8 mg, Lidocaine %2 ampoule
- Where
- Tunisia
- Volunteers
- 156 people
- Sponsor
- Mongi Slim Hospital
Propofol Injection Pain
Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain
The goal of this clinical trial was to evaluate methods to prevent pain on intravenous administration of propofol during induction of anesthesia.
- Trial name
- BBLP (NCT07285980)
- Testing
- propofol, Lidocaine - Propofol Mixture, Lidocaine - Bier Block
- Where
- Tunisia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Asma Ladib
Propofol Injection Pain, Rocuronium Injection Pain
Lidocaine, Paracetamol, and Dexmedetomidine for Rocuronium Injection Pain
Propofol and rocuronium may cause pain during intravenous injection. Various pharmacological agents are used to reduce the incidence and severity of injection pain.
- Trial name
- NCT07169227
- Testing
- Lidocaine %2 ampoule, Dexmedetomidine, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Baskent University
Preventing Propofol Pain on Injection
Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain
Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting…
- Trial name
- NCT07116304
- Testing
- Lidocaine, a local anaesthetic., Parecoxib 40mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Propofol Injection, Pain
Modulation of Propofol Injection Pain by Rubbing and Distraction
This prospective randomized controlled study will be conducted to evaluate the effects of rubbing and distraction on the incidence and severity of propofol injection pain and compare them with the standard intravenous lidocaine…
- Conditions
- Propofol Injection, Pain, Rubbing, Distraction
- Trial name
- NCT06643832
- Testing
- Rubbing Distraction, Lidocaine (drug), Saline
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Pain, During Injection of Propofol for Induction of Anesthesia
Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia
This research will be carried out in order to determine the optimal lidocaine dose in propofol lidocaine mixture to prevent pain on propofol injection during induction of general anesthesia using a modified Dixon's up-and-down…
- Trial name
- NCT05898061
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pain Syndrome, Propofol Infusion Syndrome
Warm Patch Decrease Propofol Injection Pain
Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection.
- Conditions
- Pain Syndrome, Propofol Infusion Syndrome, Injection Site Irritation
- Trial name
- NCT04555980
- Testing
- Warming patch, Cotton patch
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First People's Hospital of Chenzhou
Pain on IV Injection of Propofol.
Combining Placing a Synera Patch With Propofol/Lidocaine Mixture to Decrease Pain With IV Propofol Injection
The main objective is to evaluate if combining placing the Synera patch and using Propofol /Lidocaine mixture will further decrease the pain associated with the IV injection of Propofol.
- Trial name
- NCT02240628
- Testing
- Lidocaine/tetracaine transdermal patch, Saline, Lidocaine
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pain on Injection of Propofol,Lidocaine, Alkalinized Lidocaine
Pain on Injection of Propofol: a Comparison of Lidocaine and Alkalinized Lidocaine
Aim: The aim of this study was to compare the efficacy of pretreatment 0.5 mg/kg lidocaine and 0.5 mg/kg alkalinized lidocaine for prevention of propofol induced pain.
- Trial name
- NCT01773044
- Testing
- alkalinized lidocaine, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain Due to Propofol Injection, Hemodynamic Changes Due to Propofol Injection
The Effect of Combined Ephedrine and Lidocaine Pretreatment on Pain and Hemodynamic Changes Due to Propofol Injection
Objectives: Injection pain and hypotension are two main adverse effects of propofol which distresses patient. The aim of this prospective double blind study was to compare the effect of ephedrine -lidocaine combination with…
- Trial name
- NCT01186549
- Testing
- Ephedrine 30microgram/kg, lidocaine0.5mg/kg -ephedrine30 micrograms/kg, ephedrine 70 microgram/kg
- Where
- Iran
- Volunteers
- 165 people
- Sponsor
- Qazvin University Of Medical Sciences
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Intravenous Propofol Injection
Effect of Dexmedetomidine on Pain Due to Propofol Injection
Propofol is commonly used IV anesthetic, it has been formulated in a concentration of 10 mg/ml in a fat emulsion consisting of 10% soybean oil (long-chain triglycerides).
- Trial name
- NCT01463332
- Testing
- I.V injection of 10 ml normal saline, I.V injection with 0.25mic/kg of dexmedetomidine, I.V injection of 0.50mic/kg of dexmedetomidine
- Volunteers
- 150 people
- Sponsor
- KVG Medical College and Hospital