Clinical trials: Prolonged Grief Disorder
Grief Disorder, Prolonged
A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department
In France, a study has reported that about 0.2% of patients visiting the ED died in the ED. A large survey of 145 EDs in 3 French speaking countries has reported that a median of 2 patients dies each week in each ED and its…
- Trial name
- MYRIADE (NCT06733974)
- Testing
- Multi-faceted Intervention
- Where
- France
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prolonged Grief Disorder (PGD)
F-PGT - Prolonged Grief Treatment for Families Affected by Suicide
This pilot open trial is being done to better understand the needs of families who have lost a parent to suicide at least a year ago and who have children ages 8-14 and to develop and test Family-Prolonged Grief Treatment…
- Trial name
- F-PGT (NCT07318090)
- Testing
- F-PGT
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Prolonged Grief Disorder
Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder
The goal of this clinical trial is to pilot the effectiveness of an 8-week standardized Mindfulness Training program to decrease the psychiatric and somatic symptoms of prolonged grief disorder (PGD) and to examine changes in…
- Trial name
- CALM-NiPS (NCT06017765)
- Testing
- Meditation Training, Waitlist
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Prolonged Grief Disorder
Diagnostic Tools for Identifying Prolonged Grief
Development and validation of first clinical diagnostic interview for assessing Prolonged Grief Disorder (PGD) with the ICD 11 and DSM 5 Tr criteria.
- Trial name
- NCT05365139
- Testing
- Structured clinical diagnostic interview for PGD (PGD-I)
- Where
- Denmark
- Volunteers
- 124 people
- Sponsor
- University of Aarhus
Grief, Grief Disorder, Prolonged
Families Left Behind
The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief.
- Conditions
- Grief, Grief Disorder, Prolonged, Overdose Accidental, Substance Use Disorders
- Trial name
- NCT06854757
- Testing
- RIVER, Enhanced care as usual
- Where
- 4 sites in United States
- Volunteers
- 340 people
- Sponsor
- RAND
Prolonged Grief Disorder
Treatment of Prolonged Grief Disorder in Combat Veterans
The purpose of this study is to compare the efficacy of an experimental treatment (termed BATE-G) for Prolonged Grief Disorder (PGD) in Veterans compared to the current, VA-approved standard of care treatment.
- Trial name
- PGD (NCT02283333)
- Testing
- BATE-G, Standard Treatment
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- VA Office of Research and Development
Cervix Cancer, Uterine Cancer
Prolonged Grief and Perception of Femininity in Gynecological Cancer Patients
The aim of this study is to determine the effect of the 'Feminine Identity Improvement Program', based on cognitive behavioral and expressive techniques applied to gynecological cancer patients, on prolonged grief reactions and…
- Conditions
- Cervix Cancer, Uterine Cancer, Ovarian Cancer, Endometrial Cancer
- Trial name
- NCT05529303
- Testing
- Such as art therapy, play therapy, breathing techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kevser Pamuk
Prolonged Grief Disorder
Psilocybin for Prolonged Grief Disorder
The primary purpose of this study is to explore the feasibility of conducting a clinical trial on the effects of psilocybin for individuals with prolonged grief disorder (PGD).
- Trial name
- NCT06724289
- Testing
- Psilocybin 25 mg, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Prolonged Grief Disorder
Mechanisms Underlying Late-Life Prolonged Grief Disorder
After losing a loved one, most successfully navigate acute grief and adapt to the loss within about 1 year, but in about 10%, prolonged grief disorder (PGD) ensues.
- Trial name
- NCT07738133
- Testing
- Iyengar Yoga, Health Education Control, Waitlist Control to Crossover
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Medical College of Wisconsin
Grief Disorder, Prolonged
Feasibility and Efficacy of Individual SH+ Intervention
The central aim of this research is to execute a randomized controlled trial (RCT) to assess the impact and effectiveness of the individually-delivered SH+ intervention among earthquake survivors in Türkiye.
- Trial name
- NCT06091540
- Testing
- Feasibility and Efficacy of Individual SH+ Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Koç University
Prolonged Grief Disorder (PGD)
Technology-supported Interventions for Prolonged Grief Disorder (PGD)
The main aim of this project is to test the efficacy of two formats of delivering an internet- based treatment(GROw) for Prolonged Grief Disorder (PGD) in order to enhance treatment adherence: in a blended format (that combines…
- Trial name
- NCT06932120
- Testing
- Internet-based treatment (GROw) combined with face-to-face videoconferencing sessions with a therapist in BF-GROw group, Internet-based treatment (GROw) supported by the App developed which contains the EMA and EMI tools in iGROw group.
- Where
- 2 sites in Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Artificial Intelligence (AI), Prolonged Grief Symptoms
AI-GF-GNW on Prolonged Grief Reactions
Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved…
- Conditions
- Artificial Intelligence (AI), Prolonged Grief Symptoms, Depression - Major Depressive Disorder, Anxiety
- Trial name
- NCT07589088
- Testing
- AI-Assisted Grief-Focused Guided Narrative Writing, No-Feedback Guided Narrative Writing, Free Writing
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Peking University
Prolonged Grief Disorder
LIVIA 2.0 : A RCT Of Two French Internet Intervention For Adults Struggling With Prolonged Grief Symptoms
The investigators aim to compare the efficacy of an IBI targeting complicated grief symptoms (LIVIA 2.0) compared to an already investigated IBI (LIVIA 1) using a guidance on demand design in a randomised controlled trial (RCT).
- Trial name
- NCT05219760
- Testing
- LIVIA
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Debrot Anik
Posttraumatic Stress Disorder, Prolonged Grief Disorder
Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care
The experience of a loved one's stay in a COVID-19 intensive care unit (ICU), either intubated or on respiratory support, forces family caregivers (hereafter 'caregivers') to face core existential fears, such as uncertainty and…
- Conditions
- Posttraumatic Stress Disorder, Prolonged Grief Disorder, COVID
- Trial name
- CO-CarES (NCT04409821)
- Testing
- Tele-delivered psychological intervention
- Where
- 6 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief)
P-CRP for Recent-Onset Severe Trauma
The purpose of this retrospective study was to evaluate the effectiveness of a new psychotherapy technique called Psychological Cognitive Reprocessing Procedure (P-CRP) in treating trauma symptoms.
- Conditions
- Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief), Stress Disorder - Post-traumatic (Acute)
- Trial name
- P-CRP (NCT07360990)
- Testing
- Psychological-cognitive reprocessing procedure (P-CRP)., Expressive Narrative and Symbolic Drawing (ENSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Zahide Betül Baydar
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Grief, Post Traumatic Stress Disorder PTSD
EMDR Grief Protocol for Traumatic Grief After Earthquake-Related Loss
This pilot randomized controlled study evaluated the effectiveness of the EMDR Grief Protocol in adults who experienced the loss of a loved one in the February 6, 2023 Kahramanmaraş earthquakes.
- Conditions
- Traumatic Grief, Post Traumatic Stress Disorder PTSD, Emotional Processing
- Trial name
- NCT07776769
- Testing
- EMDR Grief Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul Bilgi University
Grief
Adolescent Suicide Loss Survivors Grief Intervention Group
This study will provide evidence-based recommendations for designing interventions tailored to adolescents dealing with suicide loss.
- Trial name
- NCT07151092
- Testing
- Adolescent Grief Group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Prolonged Grief Disorder
My Grief - an App for Parents With Prolonged Grief After Losing a Child to Cancer
Bereaved parents are at increased risk of developing mental and physical health problems and bereavement is even associated with an increased risk of mortality, especially in mothers.
- Trial name
- NCT04552717
- Testing
- My Grief
- Where
- Sweden
- Volunteers
- 248 people
- Sponsor
- Uppsala University
Naltrexone HCl 50 MG Oral Tablet, Placebo
Naltrexone for Prolonged Grief Disorder
This is a study to see how effective oral naltrexone is as treatment for prolonged grief disorder (PGD). Participants will take their assigned medication for 8 weeks, with monthly visits to assess symptom severity, social…
- Trial name
- NPGD (NCT06140420)
- Testing
- Naltrexone Oral Product
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Texas Tech University