Clinical trials: Prolapse; Female
Constipation, Surgical Procedure, Unspecified
Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation.
- Conditions
- Constipation, Surgical Procedure, Unspecified, Prolapse; Female
- Trial name
- NCT06159777
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University Hospitals Cleveland Medical Center
Uterine Prolapse
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term…
- Trial name
- PREMIER (NCT05063331)
- Testing
- Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- University Hospitals Cleveland Medical Center
Disability Physical, Urinary Incontinence
Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
Cystocele, a protrusion of the bladder, happens while the bladder descends into the vagina. There are more than one underlying causes for the development of cystocele ensuing in weak point of the muscles and the connective tissue…
- Conditions
- Disability Physical, Urinary Incontinence, Prolapse
- Trial name
- NCT05474495
- Testing
- Pelvic floor muscle training, Transverse abdominas strength training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Cystocele
Transvaginal Treatment of Symptomatic Cystocele Grade II-III
This observational study will evaluate treatment of symptomatic cystocele grade II-III with Cousin Biomesh and Allium Medical Endofast Reliant. Data about 100 patients will be collected.
- Trial name
- BCR (NCT02272322)
- Testing
- cystocele repair with biomesh soft prolaps and endofast reliant
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Slabbaert Koen
Pelvic Organ Prolapse
The Development of De-novo Stress Urinary Incontinence After Stage II-III Pelvic Organ Prolapse Surgery
Surgery for Stage II-III Pelvic organ prolapse
- Trial name
- NCT03221725
- Testing
- sacrospinous ligament fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Prolapse, Vaginal
Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis Surgery
This prospective observational study aims to evaluate changes in the vesicourethral angle using transperineal ultrasound before and after colpocleisis surgery, and to assess the relationship of these changes with the development…
- Trial name
- colpocleisis (NCT07071818)
- Testing
- Colpocleisis Group
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Prolapse; Female, Prolapse, Vaginal
What Affects Willingness to Self-manage a Pessary?
Pessary self-management is defined as the patient's ability to remove and reinsert their pessary themselves at home. Previous research has suggested that some women may prefer being able to remove and reinsert their pessary as…
- Trial name
- NCT05750615
- Testing
- Uncertain what intervention will be co-created
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- Manchester University NHS Foundation Trust
Pelvic Organ Prolapse, Stage III and IV High Grade Pelvic Organ Prolapse
Efficacy/Safety of Urogynecology Synthetic Mesh Surgery
This is a retrospective cohort study, aiming at analyzing the efficacy and safety of mesh surgery in pelvic organ prolapse. The synthetic mesh for pelvic organ prolapse include transvaginal mesh or laparotomy, laparoscope, or…
- Trial name
- NCT05682989
- Testing
- Urodynamic investigations before and after a mesh surgery protocol., Urodynamic investigations before and after a robotic-assisted sacrocolpopexy protocol., Urodynamic investigations before and after a hysterectomy with trans-vaginal mesh repair
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Mackay Medical College
Lower Urinary Tract Symptoms, Pelvic Organ Prolapse
Population-based Estimates of Medical Comorbidities in Women With Lower Urinary Tract Symptoms or Pelvic Organ Prolapse
The purpose of this study is to investigate the comorbidities of lower urinary tract symptoms or pelvic organ prolapse in a nationwide population-based data in Taiwan during the study period of 2001-2010, a total of 10 years.
- Trial name
- NCT01590576
- Where
- Taiwan
- Volunteers
- 2,500 people
- Sponsor
- Far Eastern Memorial Hospital
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Prolapse Genital, Prolapse Uterovaginal
Posterior Mesh Fixation at the Levator Ani Level in Apical Pelvic Organ Prolapse
This is a prospective, randomized, multicenter, non-inferiority trial including women with stage II-IV apical pelvic organ prolapse (POP), classified according to the POP-Q system.
- Conditions
- Prolapse Genital, Prolapse Uterovaginal, Prolapse; Female
- Trial name
- FIMEA (NCT07194343)
- Testing
- Laparoscopic colposacropexy with levator ani muscle mesh fixation, Simplified modification of laparoscopic colposacropexy
- Where
- 6 sites in Spain
- Volunteers
- 190 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
This study is a randomized controlled trial designed to assess the rate of failure of voiding trials in the early and late post-operative period within patients who underwent outpatient pelvic floor surgery that failed initial…
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
- Trial name
- NCT03048682
- Testing
- Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Prolapse, Vaginal
Women's Knowledge and Attitudes to Use of Mesh in Gynaecological Surgery
This is a questionnaire study that is being performed to ascertain the knowledge and attitudes of women towards use of mesh in gynaecological surgery.
- Trial name
- NCT03527082
- Testing
- Questionnaire
- Volunteers
- 150 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Pelvic Organ Prolapse
Xenform Postmarket Surveillance Study
To compare transvaginal repair with a biologic graft to traditional native tissue repair in women surgically treated for anterior and/or apical pelvic organ prolapse.
- Trial name
- Xenform (NCT01945580)
- Testing
- Prolapse Repair
- Where
- 25 sites in United States
- Volunteers
- 374 people
- Sponsor
- Boston Scientific Corporation
Stress Urinary Incontinence, Vaginal Prolapse
BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)
The goal of this clinical trial is to learn if retropubic midurethral sling (RP-MUS) or bulkamide injection (PAHG) at the time of pelvic organ prolapse repair is better from the patient's perspective.
- Trial name
- BELIEVE (NCT06754046)
- Testing
- RP-MUS, PAHG
- Where
- United States
- Volunteers
- 476 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence
This study evaluates the addition of a laparoscopic Burch colposuspension procedure at the time of laparoscopic sacrocolpopexy to prevent stress urinary incontinence.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Urinary Incontinence, Urge, Bowel Dysfunction
- Trial name
- MICRO (NCT03841513)
- Testing
- Laparoscopic Burch Colposuspension
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Cystocele
A Novel Suturing Technique of Cystocele Treatment
The rug weaving-like plication technique may offer a viable alternative for cystocele repair without mesh, utilizing natural tissue.
- Trial name
- cystosel (NCT06410469)
- Testing
- rug weaving-like plication technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ankara City Hospital Bilkent
Pelvic Organ Prolapse
Comprehensive Nursing Care Protocol for Women With Pelvic Organ Prolapse and Urinary Incontinence: A Global Perspective
Pelvic organ prolapse is the descent of pelvic structures into the vagina due to ligament or muscular weakness. Pelvic organ prolapse (POP) is subcategorized according to the compartment of descent.
- Trial name
- Nurse Protocol (NCT06639217)
- Testing
- a comprehensive nursing care protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Vaginal Vault Prolapse, Uterine Prolapse
Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment
This prospective cohort study investigates the surgical outcomes of laparoscopic pectopexy and laparoscopic colporraphy performed at the Wellbeing Services County of South Ostrobothnia.
- Conditions
- Vaginal Vault Prolapse, Uterine Prolapse, Cystocele, Midline, Rectocele; Female
- Trial name
- NCT06902909
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital
Cystocele
Changes of Pad Weight Results and Urethral Pressure Profiles After Reduction of Cystocele by Vaginal Gauze Packing
The purpose of this study is to retrospectively review the impact of vaginal packing on the urodynamic studies, especially for urethral pressure profiles.
- Trial name
- NCT01559558
- Testing
- vaginal packing
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Taiwan University Hospital