Clinical trials: Problem Management Plus
Depression, Economic Vulnerability
ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression
The goal of this randomized controlled trial is to compare the impact of an integrated intervention combining poverty alleviation and depression treatment to depression treatment alone, in low income rural Bangladeshi women with…
- Conditions
- Depression, Economic Vulnerability, Anxiety, Culture Specific Symptoms
- Trial name
- NCT06295250
- Testing
- Manualized Group Based Psychotherapy, Poverty Alleviation
- Where
- Bangladesh
- Volunteers
- 600 people
- Sponsor
- University of Massachusetts, Worcester
Depression, Anxiety, Trauma
Problem Management Plus Mindfulness-informed Legal Education for Addressing Gender-based Violence and Improving Parenting
Gender-based violence and, more specifically, domestic violence is a prevalent problem globally and in Nigeria. Its effect significantly impacts women and also the wellbeing of their families.
- Conditions
- Depression, Anxiety, Trauma, Anxiety, Parenting Intervention
- Trial name
- PM+MiLE (NCT06601023)
- Testing
- Psychosocial intervention
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Depression, Anxiety Disorders
Pilot Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19
This is a pilot feasibility study of remotely delivered Problem Management Plus, a low-intensity psychological intervention, delivered in five sessions to adults affected by crisis.
- Conditions
- Depression, Anxiety Disorders, Psychological Distress
- Trial name
- PM+ (NCT04617262)
- Testing
- Remote Problem Management Plus
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The New School
Treatment Resistant Depression, Problem Management Plus
An Intervention Study of Anhedonia and Pain Empathy in Depression
Brain Network Mechanism of Pain Empathy and Anhedonia in Patients With Depression by Group Problem Management Plus Intervention.
- Conditions
- Treatment Resistant Depression, Problem Management Plus, Event-Related Potentials
- Trial name
- NCT05355142
- Testing
- PM+
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Anhui Medical University
Cancer-related Problem/Condition, Cancer-related Fatigue
Engagement and Acceptability of the Untire mHealth App
The aim of this study will be to assess the engagement and acceptability of the Untire mHealth intervention for adults with cancer related fatigue. Acceptability will be assessed after 2, 4, 6 and 12 weeks of app use.
- Trial name
- NCT05891431
- Testing
- Untire mobile app
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Bath
Distress, PTSD
Scaling-up Psychological Interventions With Syrian Refugees in Switzerland (STRENGTHS_CH): RCT
The current refugee crisis across the Middle East and Europe has large effects on individual refugees' psychological well-being, as well as on the healthcare systems of countries hosting refugees.
- Conditions
- Distress, PTSD, Anxiety, Depression
- Trial name
- NCT04574466
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Depression
Competency-based Training in Problem Management Plus: a Randomized Controlled Trial
The proposed study in Nepal will evaluate if non-specialists participating in Equip-based Problem Management Plus training show greater competencies compared to non-specialists participating in standard Problem Management Plus…
- Trial name
- EQUIP-PM+ (NCT04954872)
- Testing
- Standard Problem Management Plus training (training as usual), Equip-based Problem Management Plus training
- Where
- Nepal
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- George Washington University
Psychological Distress, PTSD
Feasibility and Acceptability of BRIGHT
Refugees and asylum seekers (RAS) face numerous stressors and adversities which put them at risk for developing mental health problems. However, access to adequate mental health care in host countries is limited.
- Conditions
- Psychological Distress, PTSD, Trauma, Psychological
- Trial name
- NCT06397105
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- University of Zurich
Anxiety, Depression
Implementation of Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: Pilot
To implement Problem Management Plus (PM+) in Syrian refugees with this pilot study in Turkey with the aim of informing the definitive RCT about drop-out rates and estimated effect sizes.
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- STRENGTHS (NCT03567083)
- Testing
- Problem Management Plus (PM+)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul Sehir University
Psychological Distress, Depression
A Scalable Psychological Intervention to Reduce Psychological Distress Among Healthcare Workers
Rationale: The COVID-19 pandemic has impacted the mental health of healthcare workers (HCWs). This study combines two low-intensity psychological interventions developed by the World Health Organization (Doing What Matters [DWM]…
- Conditions
- Psychological Distress, Depression, Anxiety
- Trial name
- RESPOND-HCW (NCT04980326)
- Testing
- Doing What Matters (DWM), Problem Management Plus (PM+), Psychological First Aid (PFA)
- Where
- 2 sites in Spain
- Volunteers
- 232 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Mental Health, Stress, Psychological
Syrian Refugee Young Adults as Community Mental Health Workers-Lebanon
In this pilot study, we aim to evaluate the feasibility, acceptability and fidelity of Syrian refugee young adults as community mental health workers (Y-CMHW), and the impact of this work on outcomes of wellbeing, coping and…
- Trial name
- NCT05265611
- Testing
- low intensity psychosocial intervention - Problem Management Plus (PM+), Tutoring
- Where
- Lebanon
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Rema Afifi
HIV Infections
Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV
This study will determine whether a managed problem solving intervention can help patients with HIV better follow their anti-HIV drug regimen and can control HIV better than the standard of care.
- Trial name
- MAPS (NCT00130273)
- Testing
- Managed problem solving, Standard care
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Pennsylvania
Anxiety, Depressive Symptoms
Rare Group Problem Management Plus
Participants are being asked to be in the study if they are the parent or legal guardian of a child (>1 year or <18 years old) with a rare condition.
- Conditions
- Anxiety, Depressive Symptoms, Post-traumatic Stress Disorder, Problems Psychosocial
- Trial name
- Group PM+ (NCT06548022)
- Testing
- Rare Group Problem Management Plus
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's National Research Institute
Attention Deficit Hyperactivity Disorder, Attention Deficit and Disruptive Behavior Disorders
Efficacy of a Brief Behavioral Intervention to Treat ADHD and Disruptive Behaviors In Preschoolers
The purpose of this study is to test the intervention using a more rigorous randomized controlled trial design in order to demonstrate its efficacy compared to a wait-list control, thus ensuring that change in behavior does not…
- Trial name
- NCT01919073
- Testing
- Immediate Treatment Group, Delayed Treatment Group
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Baylor College of Medicine
Well-being, Psychological Capital
Problem Management Plus for Entrepreneurs
Conflict and unrest over three decades has resulted in significant economic decline in Khyber Pakhtunkhwa (KP) and Federally Administered Tribal Areas (FATA) of Pakistan and these now rank among the poorest regions in the…
- Conditions
- Well-being, Psychological Capital, Anxiety, Depression
- Trial name
- NCT03540927
- Testing
- PM+ for entrepreneurs, Cash transfer to the Entrepreneurs
- Where
- Pakistan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Human Development Research Foundation, Pakistan
Mental Health Wellness 1
Adapting Group PM+ for Venezuelan Refugees and Migrants in Colombia
This study is a type 2 hybrid implementation design, which aims to evaluate the utility and effectiveness of an intervention while simultaneously assessing implementation outcomes, such as adoption, fidelity, and maintenance.
- Trial name
- NCT05477355
- Testing
- Group Problem Management Plus (PM+)
- Where
- Colombia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The New School
Food Allergy in Children, Caregiver Burnout
The Psychosocial Outcomes in Caregivers of Children With Food Allergy
The purpose of this study is to evaluate use of a mobile application (also commonly referred to as an app) designed to support caregivers of children with newly diagnosed food allergy. This study has 2 phases.
- Conditions
- Food Allergy in Children, Caregiver Burnout, Psychosocial Problem, Family Research
- Trial name
- FASST (NCT04512924)
- Testing
- Enhanced mobile app with standard of care and education, Enhanced mobile app with standard of care, education and support resources
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anxiety Disorders, Psychological Distress
Feasibility and Acceptability of Problem Management Plus (PM+) for Prisoners in the Netherlands - a Pilot RCT
The goal of this pilot randomised controlled trial is to evaluate the feasibility and acceptability of the - specifically to the prison context adapted - World Health Organization's Problem Management Plus (PM+) intervention for…
- Conditions
- Anxiety Disorders, Psychological Distress, Depressive Disorder
- Trial name
- PROSPER (NCT05927987)
- Testing
- Problem Management Plus (PM+)
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- VU University of Amsterdam
Cancer-related Problem/Condition, Cancer, Breast
A Self-Management Energy Conservation Program for Cancer-Related Fatigue
The purpose of this pilot study is to examine a 12-week self-management energy conservation program (ECAM)'s effects on fatigue, and secondarily on sleep, physical activity, anxiety and depression, self-efficacy, and beliefs…
- Conditions
- Cancer-related Problem/Condition, Cancer, Breast, Fatigue
- Trial name
- NCT03282214
- Testing
- Self-management energy conservation
- Where
- 2 sites in Thailand
- Volunteers
- 18 people
- Sponsor
- University of Michigan
Mental Health Issue, Inflammatory Bowel Diseases
RxWell in Pediatric IBD for Disease Management and Transition Readiness
Evaluate the feasibility and acceptability of adapted coached RxWell for patients ages 16-25. Adapt and beta test the modified RxWell product to include chronic disease management and transition readiness.
- Trial name
- NCT05461014
- Testing
- dCBI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh