Clinical trials: Probiotic Intervention
Dietary Intervention
Growth of Infants Fed New Starter Formula
The purpose of this study is to assess the growth of infants fed a novel starter formula containing synbiotics and different protein levels, compared to a standard starter infant formula, during the first four months of life.
- Trial name
- NCT01079208
- Testing
- test starter infant formula, test starter infant formula with synbiotics, control standard formula
- Where
- 3 sites in United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity (Disorder), GLP-1 Receptor Agonist Treatment
Probiotics in Obese Patients Treated With Semaglutide
This randomized, double-blind, placebo-controlled trial evaluated the effects of a four-strain probiotic formulation in adults with obesity receiving semaglutide.
- Conditions
- Obesity (Disorder), GLP-1 Receptor Agonist Treatment, Probiotic Intervention, Diabetes Mellitus Type 2
- Trial name
- ProSem (NCT07847593)
- Testing
- Four-strain probiotic formulation
- Where
- 3 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Psoriasis
Intervention Study to Evaluate a Probiotic in Mild to Moderate Psoriasis Patients
This study evaluates the efficiency of a probiotic as a coadjuvant in the conventional treatment of mild to moderate plaque psoriasis.
- Trial name
- NCT02576197
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Biopolis S.L.
Gut Function
Probiotic Intervention for Gut Function
The effect of probiotics on gut function in healthy subjects.
- Trial name
- NCT05155449
- Testing
- Probiotics
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Probi AB
Seasonal Allergic Rhinitis
Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms
The purpose of the current study is to evaluate the efficacy of administering a probiotic in adult human subjects suffering from allergic rhinitis during seasonal grass pollen exposure.
- Trial name
- NCT01653652
- Testing
- Probiotic, Maltodextrin
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Société des Produits Nestlé (SPN)
Gastrointestinal Function
Probiotic Intervention in Constipation
To evaluate the effects of probiotic intervention on gastrointestinal function in patients with constipation after 4 weeks of treatment, and to explore its potential effects on immune status and bone metabolism.
- Trial name
- NCT07462494
- Testing
- GUT99 1, GUT99 2
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Gut Function, Occasional Constipation
Probiotic Intervention for Occasional Constipation
The goal of this clinical trial is to study the effect of probiotics on gut function in subjects with occasional constipation. The main question it aim to answer is if intake of probiotics will decrease the transit time.
- Trial name
- NCT06444139
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Probi AB
Breast Pain
L.Fermentum CECT5716 in Treatment of Breast Pain
The main objective of this intervention study is to evaluate the efficacy of Lactobacillus fermentum CECT5716 to reduce the presence in the milk of genera Staphylococcus and Streptococcus as risk factors for mastitis in women…
- Trial name
- NCT02093338
- Testing
- Lactobacillus fermentum CECT5716
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Biosearch S.A.
Infections, Upper Respiratory Tract
The Effect of a Probiotic on Upper Respiratory Tract Infections
This study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group study in healthy children aged 2-6 years.
- Trial name
- PIP-U (NCT03636191)
- Testing
- Probiotic strain
- Where
- United Kingdom
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Healthy
A Study of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis
The purpose of this study is to assess the effect of B. infantis (EVC001) versus placebo supplementation, in healthy breastfed infants at risk of developing atopic dermatitis (AD), on cumulative incidence of physician-diagnosed…
- Trial name
- NCT04662619
- Testing
- B. infantis
- Where
- Finland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Rhinitis, Allergic, Seasonal
Probiotics for Birch Pollen Allergy
Birch pollen allergy is one of the most common forms of respiratory allergy in the Nordic countries. Treatment consists of antihistamine use. Specific probiotic strains have been observed to modulate the immune system.
- Trial name
- NCT00746226
- Testing
- Lactobacillus acidophilus and Bifidobacterium lactis
- Where
- Finland
- Volunteers
- 47 people
- Sponsor
- Danisco
Oral Health
The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste
Randomized double-blind, placebo-controlled trial on the effects of an oral probiotic intervention with or without a novel ADP-1 toothpaste Objective Determine the safety and effectiveness of oral probiotic intervention with or…
- Trial name
- NCT05330793
- Testing
- Oral probiotic
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- USANA Health Sciences
Mastitis, Breast Milk
Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis
The aim of the present study is to evaluate the effect of consumption during pregnancy and the lactation period of the probiotic L. fermentum CECT5716 on the incidence of mastitis.
- Conditions
- Mastitis, Breast Milk, Lactation, Women's Health
- Trial name
- NCT04032899
- Testing
- Lactobacillus fermentum CECT5716, Maltodextrin
- Where
- 3 sites in Spain
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Body Weight, Body Height
Safety and Tolerance Study of Three Probiotic Strains in Infants
Study to evaluate the safety and tolerance of three probiotic bacteria intake by healthy infants. Participants are divided at random and unknown to the researchers, in four groups, three of which receive one of three probiotic…
- Conditions
- Body Weight, Body Height, Head Circumference
- Trial name
- PROBINFANT (NCT02215304)
- Testing
- Bifidobacterium longum ssp infantis R0033, Lactobacillus helveticus R0052, Bifidobacterium bifidum R0071
- Where
- Spain
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Irritable Bowel Syndrome
Vetal Laban Intervention Trial Assessing Bowel Symptoms
A two month intervention trial assessing the effect of Vetal Laban containing L. acidophilus on enhancing functional bowel wellbeing among subjects with irritable bowel syndrome (IBS).
- Trial name
- KF_2013 (NCT01887483)
- Testing
- Vetal Laban active
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Danisco
Intestinal Permeability
The Effect of Probiotic Intervention on Intestinal Permeability
This trial is a single-site, randomised, double blind, placebo-controlled, two-armed parallel-group trial in healthy adult volunteers.
- Trial name
- NCT03027583
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Stress
Probiotic Intervention for Acute Stress
Efficacy of probiotics on acute stress
- Trial name
- NCT03284905
- Testing
- Probiotic supplement
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Probi AB
Crying
Feeding Intervention for Infants With Crying
The purpose of the study is to assess if infants who have excessive crying and fussing have less of these symptoms when fed a formula containing a probiotic compared to those fed a standard infant formula.
- Trial name
- NCT01017991
- Testing
- Milk based infant formula with probiotic, Milk based infant formula
- Where
- 9 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Vaginal Infection
Interventional Study to Evaluate the Effect of the Oral Administration of L.Plantarum on Vaginal Microbiota
Vaginal microbiota is abundantly colonized by Lactobacillus genera. When vaginal microbiota gets altered, opportunistic microorganisms may proliferate and become abundant species giving rise to dysbiosis.
- Trial name
- NCT04461782
- Testing
- Lactobacillus plantarum
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Surgery--Complications, Molar, Third
Probiotic Intervention After Surgical Removal of Mandibular Third Molars
Single-center, double-blind, randomized trial of probiotics L. plantarum KABP-051 (CECT7481) and L. brevis KABP-052 (CECT7480) taken twice daily for 7 days after surgical removal of both mandibular 3rd molars.
- Trial name
- NCT04203771
- Testing
- Probiotic AB-DENTALAC, Surgical removal of mandibular third molars at baseline, Ibuprofen
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA