Clinical trials: Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
First-in-human Single Ascending Dose Study of LNA043 in Patients Scheduled for Total Knee Replacement
This study is designed to evaluate the safety and tolerability of ascending single doses of LNA043 given intra-articularly into the human knee joint prior to its removal at total knee replacement surgery.
- Trial name
- NCT02491281
- Testing
- LNA043
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
Cold and Compression Post TKA
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14…
- Trial name
- NCT07023185
- Testing
- Cold and Compression, SOC (Standard of care)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ochsner Health System
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery, Osteoarthritis (OA) of the Knee
Does the Use of Patient Specific Instrumentation Improve Outcomes in Knee Arthroplasty Surgery for Osteoarthritis When Compared to Standard Posterior Referenced Instrumentation?
The goal of this randomized study is to see if using patient-specific instruments (PSI) during total knee replacement surgery improves outcomes compared to standard instruments.
- Trial name
- PRIPSI (NCT06720012)
- Testing
- Patient specific instrumentation (PSI), Conventional instruments, Cemented Total Knee Arthroplasty
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Vastra Gotaland Region