Clinical trials: Primary Insomnia, active
Insomnia, Insomnia (Moderate)
ASV Therapy for Insomnia
This will be a single center, prospective study designed to evaluate the effect of adaptive servo ventilation therapy on insomnia severity among patients with moderate to severe chronic insomnia.
- Trial name
- NCT07011966
- Testing
- ASV therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- ResMed
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Primary Insomnia
Acupoint Selection Based on Meridian Theory in Primary Insomnia of Liver Depression and Spleen Deficiency Type
The classical literature combined with modern medicine to select acupoints, in order to intervene in the autonomic nerve function of the superior cervical sympathetic ganglion as an opportunity, put forward the meridian acupoints…
- Trial name
- NCT06782815
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Chuanlong Zhou
Migraine Disorder, Low Back Pain
Sleep Hygiene Education to Improve Sleep in Chronic Migraine and Back Pain
The goal of this clinical trial is to learn whether sleep hygiene education can improve sleep quality and reduce pain in adults with migraine and/or chronic lower back pain.
- Conditions
- Migraine Disorder, Low Back Pain, Chronic Pain, Sleep Disorder (Disorder)
- Trial name
- NCT07425964
- Testing
- Sleep Hygiene Education
- Volunteers
- 100 people
- Sponsor
- Aalborg University
Insomnia
Sleep Restriction Therapy for Insomnia in Primary Health Care
The recommended treatment for insomnia, cognitive behavioral therapy for insomnia (CBT-I), is effective. However, its long, multi-component nature makes it challenging to implement in ordinary primary care, where most people are…
- Trial name
- NCT04975776
- Testing
- Sleep restriction therapy, Sleep hygiene
- Where
- Sweden
- Volunteers
- 104 people
- Sponsor
- Region Stockholm
Caregivers
Cereset Research for Caregivers
Caregivers experience high levels of prolonged stress that can lead to chronic problems with health, including increased risk of cardiovascular disease that is linked to autonomic dysregulation.
- Trial name
- NCT05209438
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Primary Insomnia
Comparative Efficacy of Magnesium Supplement and Melatonin Congener in Young Adults With Primary Insomnia
Sleep is essential for our overall health and well-being, much like food and water. It plays a vital role in numerous bodily functions.
- Trial name
- NCT06996171
- Testing
- Magnesium glycinate, Melatonin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- CMH Kharian Medical College
Tension-Type Headache, Sleep Disturbance
Tension-type Headache and Its Association
To estimate the prevalence of tension-type headache among adults attending the outpatient clinics at Assiut University Hospitals, and to assess its association with smartphone use, sleep quality, and quality of life.
- Conditions
- Tension-Type Headache, Sleep Disturbance, Smartphone Addiction, Quality of Life
- Trial name
- NCT07779655
- Volunteers
- 199 people
- Sponsor
- Assiut University
Panic Disorder, Social Anxiety Disorder
Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
In this multicenter study, the investigators want to find out if an addition of an diagnostic assessment and possibility of treatment with guided self-help CBT can increase the treatment effects of PCBH on patient functioning and…
- Conditions
- Panic Disorder, Social Anxiety Disorder, Depression, Hypochondriasis
- Trial name
- KAIROS (NCT04900064)
- Testing
- Brief interventions, Self-help CBT
- Where
- 4 sites in Sweden
- Volunteers
- 1,242 people
- Sponsor
- Linnaeus University
Insomnia, Primary
Efficiency of Intermittent Hypoxia Intervention in Primary Insomnia
The purpose of this study was to understand the effectiveness of intermittent hypoxia in the treatment of primary insomnia.
- Trial name
- NCT07394699
- Testing
- Intermittent Hypoxia
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Insomnia, Hypnotic Dependence
Enhancing Hypnotic Medication Discontinuation in Primary Care
Many individuals with insomnia seek treatment in primary care settings, where they often receive prescription hypnotic medications as their first and sometimes only treatment.
- Trial name
- NCT06435520
- Testing
- Digital Cognitive Behavioral Therapy, Structured Medication Tapering
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- National Jewish Health
Chronic Insomnia
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity.
- Trial name
- HypERR (NCT06898099)
- Testing
- "Standard care" control group (without hypnosis), Experimental group: "E2R hypnosis"
- Where
- 35 sites in France
- Volunteers
- 136 people
- Sponsor
- Rennes University Hospital
Depressive Disorder, Major
Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized Trial
The study's primary objective is to evaluate the effectiveness of Tinazidine compared to Zolpidem in enhancing sleep quality, with secondary objectives including the assessment of adverse effects, safety profile, and patient…
- Trial name
- NCT06303076
- Testing
- Tizanidine Hcl 4Mg Tab, Zolpidem Tartrate 10 mg
- Volunteers
- 90 people
- Sponsor
- Sultan Qaboos University
Depression, Anxiety
Interactive Technological Intervention to Improve Mental Health Symptoms in Primary Health Care
This study aims to implement and evaluate a technological intervention called CONEMO to treat depressive symptoms, anxiety, and insomnia in adults who use primary health care services.
- Conditions
- Depression, Anxiety, Insomnia
- Trial name
- NCT06692842
- Testing
- CONEMO App
- Where
- Brazil
- Volunteers
- 12,400 people
- Sponsor
- University of Sao Paulo General Hospital
Depression, Insomnia
Implementation of Internet-based Psychotherapy for Symptoms of Depression, Insomnia and Anxiety in Primary Care in the Cities of Indaiatuba and Jaguariuna
The main objective of this study is to evaluate the effectiveness and success of implementing internet-based cognitive behavioral psychotherapy (iCBT) guided by a therapist for symptoms of depression, insomnia and anxiety in…
- Conditions
- Depression, Insomnia, Anxiety
- Trial name
- NCT06817109
- Testing
- interactive technological intervention for improvement of mental health symptoms in Primary Care users Health
- Where
- 2 sites in Brazil
- Volunteers
- 268 people
- Sponsor
- University of Sao Paulo General Hospital
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Insomnia, Primary, Sleep Apnea, Obstructive
Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea
This two-site randomized clinical trial will investigate and compare three treatments for insomnia in patients who have been diagnosed with and treated for sleep apnea: online cognitive behavioral therapy (OCBT)…
- Trial name
- NCT03109210
- Testing
- Online Cognitive Behavioral Therapy (OCBT), Therapist-directed Cognitive Behavioral Therapy (TCBT)
- Where
- 2 sites in United States
- Volunteers
- 384 people
- Sponsor
- National Jewish Health
Primary Hypertension
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
This study aims to determine the effects of lavender oil inhalation on anxiety, sleep quality, and blood pressure in patients with primary hypertension. The study is designed as a double-blind randomized controlled trial.
- Trial name
- NCT07192783
- Testing
- Lavender
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ardahan University
Insomnia, Primary
Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep
Insomnia is generally believed to be caused by excessive arousal of the brain and body. Rather than transitioning normally and quickly from wakefulness to sleep, individuals with insomnia tend to enter into a self-perpetuating…
- Trial name
- NCT04953559
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University