Clinical trials: Priapism
Priapism, Anemia, Sickle Cell
Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence
Priapism, a prolonged erection of the penis, is a medical issue that often affects men with sickle cell disease. The purpose of this study is to collect demographic and clinical information on priapism by interviewing men with…
- Trial name
- NCT00300235
- Where
- 27 sites in United States
- Volunteers
- 1,464 people
- Sponsor
- University of Texas Southwestern Medical Center
Sickle Cell Disease
Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises
The purpose of this study was to determine whether the investigational drug SelG1 when given to sickle cell disease patients either taking or not taking hydroxyurea was effective in preventing or reducing the occurrence of pain…
- Trial name
- SUSTAIN (NCT01895361)
- Testing
- SelG1
- Where
- 56 sites in United States, Brazil and 1 more
- Volunteers
- 198 people
- Sponsor
- Reprixys Pharmaceutical Corporation
Priapism Due to Sickle Cell Disease
A Trial for Prevention of Recurrent Ischemic Priapism in Men With Sickle Cell Disease: A Pilot Study
To conduct a randomized controlled internal pilot feasibility trial for the prevention of recurrent ischemic priapism referred to as the Priapism in Nigeria (PIN) trial.
- Trial name
- PIN (NCT05142254)
- Testing
- Tadalafil, Hydroxyurea
- Where
- 2 sites in Nigeria
- Volunteers
- 64 people
- Sponsor
- Vanderbilt University Medical Center
Sickle Cell Disease
Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal Events
Hypothesis is that the occurrence of nocturnal Vaso-Occlusive Crisis (VOC) and priapism in adults might be related to episodes of nocturnal desaturation secondary to a sleep apnea syndrome.
- Trial name
- DREPASOM (NCT02539771)
- Testing
- Polysomnography and blood sample
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Priapism
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism
The goal of the study was to evaluate the efficacy and safety of crizanlizumab in sickle cell disease (SCD) patients with priapism.
- Trial name
- SPARTAN (NCT03938454)
- Testing
- Crizanlizumab
- Where
- 13 sites in United States
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Sickle Cell Disease, Dyslipidemia
Lipid Balance in Adult Sickle Cell Patients
This study aims to describe and/or searches for, in cohorts of adult sickle cell anemia (SCA) and SC sickle cell patients living in the French West Indies and followed by SCD Reference and Competence Centers: 1-lipids profiles…
- Conditions
- Sickle Cell Disease, Dyslipidemia, Complication
- Trial name
- HDL2 (NCT05780775)
- Testing
- HDL2
- Where
- Guadeloupe
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Priapism, Sickle Cell Disease
Androgen Regulation of Priapism in Sickle Cell Disease
It is believed that when androgen (testosterone) levels are below normal there is a disturbance of normal bodily functioning that is associated with priapism in some men.
- Conditions
- Priapism, Sickle Cell Disease, Hypogonadism
- Trial name
- NCT01940718
- Testing
- Transdermal Androgel
- Where
- United States
- Sponsor
- Johns Hopkins University
Priapism
ManAgement of pRiapiSm and Its Impact on Outcomes
Priapism is a urological emergency that is defined as a prolonged penile erection lasting more than 4 h, remaining despite orgasm and in the absence of sexual stimulation.
- Trial name
- MARS (NCT04932902)
- Where
- 5 sites in Italy, Portugal
- Volunteers
- 200 people
- Sponsor
- Policlinic Hospital "G. Rodolico"
Priapism, Reperfusion Injury
Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats
The condition known in medical terminology as 'Priapism' refers to the state of erection in the male sexual organ persisting partially or completely for more than 4 hours without sexual stimulation or orgasm.
- Trial name
- NCT07391709
- Testing
- Ischemic priapism + reperfusion, Ischemic priapism + reperfusion + ALA
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Sickle Cell Disease, Priapism
Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia
This research is being done to evaluate if the phosphodiesterase type 5 (PDE5) inhibitor sildenafil has an effect on the frequency of recurrent priapism and the quality of life of males with sickle cell disease (SCD).
- Trial name
- NCT00940901
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Sickle Cell Anemia, Priapism
Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia
This research is being done to compare the effect of tadalafil with placebo (an inactive substance that looks like the study drug, but should have no effect) on the frequency of recurrent priapism (prolonged erection…
- Trial name
- NCT00538564
- Testing
- tadalafil
- Where
- United States
- Sponsor
- Johns Hopkins University