Clinical trials: Prevention
Behavior
Handheld Mirror to Improve Child's Behavior During Dental Treatment
The purpose of this study is to determine whether a handheld mirror helps to reduce child behavior problems during dental treatment. It will be tested by randomized crossover design.
- Trial name
- NCT02366520
- Testing
- handheld mirror
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Adolescent Mental Health, Psychosocial Adaptation
Trauma-Informed School Intervention for Adolescent Mental Health and Self-Injury Prevention in China
This study evaluated a school-based psychosocial adaptive capacity enhancement program for Chinese adolescents. The program was developed to support students who may have experienced childhood household dysfunction or other…
- Conditions
- Adolescent Mental Health, Psychosocial Adaptation, Childhood Household Dysfunction
- Trial name
- TISI-China (NCT07583524)
- Testing
- School-Based Psychosocial Adaptive Capacity Enhancement Program
- Where
- China
- Volunteers
- 5,787 people, healthy volunteers welcome
- Sponsor
- WU Han
Breast Cancer Prevention, Breast Cancer Diagnosis
Supine Photon-Counting CT and Contrast-Enhanced Mammography Versus Breast MRI for Pretreatment Tumor Size in Breast Cancer Candidates for Neoadjuvant Chemotherapy
Retrospective single-centre agreement study in women with biopsy-proven invasive breast cancer who underwent CEM, supine PC-CT and prone breast MRI before neoadjuvant chemotherapy. Prone MRI is the clinical reference.
- Trial name
- PC CEM MRI (NCT06843083)
- Testing
- Supine photon-counting CT (PC-CT), CEM, Prone dynamic contrast-enhanced breast MRI
- Where
- Italy
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Graziella di Grezia
Pre-Exposure Prophylaxis, Hiv
Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)
The aim of this study is to examine the effect of social media intervention on the use of pre-exposure prophylaxis (PrEP) by young men who have sex with men (YMSM) in the greater New Haven area.
- Conditions
- Pre-Exposure Prophylaxis, Hiv, Men
- Trial name
- NCT04417946
- Testing
- PrEP messages, Heath messages
- Where
- 2 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Yale University
Grief, Anxiety
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19
This study evaluates the effectiveness of an online Multi-component psychological intervention, that is focused on providing self-support to the Mexican population for the prevention of complicated grief disorder, by reducing…
- Conditions
- Grief, Anxiety, Depression, Sleep Disturbance
- Trial name
- NCT04638842
- Testing
- Online Intervention Grief COVID-19
- Where
- Mexico
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Overweight, Physical Activity
The Healthy Elementary School of the Future
Unhealthy lifestyles in early childhood are a major global health challenge. These lifestyles often persist from generation to generation and contribute to a vicious cycle of health-related and social problems.
- Conditions
- Overweight, Physical Activity, Malnutrition, Child Development
- Trial name
- THESF (NCT02800616)
- Testing
- The Healthy Primary School of the Future, The Physical Activity School
- Volunteers
- 2,349 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Obesity
Pediatric Behavioral Informatics to Prevent Cancer
The goal of this study is to do formative research which will lead ultimately to the development of a computer-based system called Tailored Information for Diet and Exercise or TIDE for short.
- Trial name
- TIDE (NCT01768533)
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Illness Absenteeism, Handwashing Behavior
Jerusalem Handwashing Study
The primary objective of this preschool intervention trial was to determine whether a hygiene program can promote handwashing and thereby reduce illness absenteeism.
- Trial name
- JHS (NCT00610376)
- Testing
- Preschool handwashing intervention program, Home component intervention
- Where
- Israel
- Volunteers
- 1,029 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Adolescent Mental Health, Physical Inactivity
Active Families, Healthy Minds: A Family-Centered School Physical Activity Program for Early Adolescents
This study evaluates the effectiveness of a family-centered school physical activity program, titled "Active Families, Healthy Minds," designed to improve mental health among early adolescents (ages 10-14) in China.
- Conditions
- Adolescent Mental Health, Physical Inactivity, Mental Well-being, Sedentary Behavior
- Trial name
- AFHM (NCT07380750)
- Testing
- Family-Supported PA Program, School-Only PA Program, Standard Physical Education
- Where
- China
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou
Psychological Distress
Compassion Cultivation Training (CCT): An Intervention for Caregivers
This study will begin a novel line of research on CCT in Denmark as a preventive intervention for caregivers of people suffering from a mental illness.
- Trial name
- NCT03730155
- Testing
- CCT intervention.
- Where
- 2 sites in Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Preeclampsia
Cornell University-Micronutrient Initiative Calcium Supplementation Study
The World Health Organization (WHO) now recommends prenatal calcium supplementation for prevention of preeclampsia in populations with inadequate dietary intake.
- Trial name
- MICA (NCT02238704)
- Testing
- Regimen A calcium and iron/folic acid, Regimen B calcium and iron/folic acid
- Where
- 16 sites in Kenya
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Cornell University
HIV Infections
Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South Africa
This study will evaluate the preventive vaccine efficacy, safety, and tolerability of ALVAC-HIV (vCP2438) + Bivalent Subtype C gp120/MF59 in HIV-seronegative South African adults over 24 months and potentially up to 36 months…
- Trial name
- HVTN702 (NCT02968849)
- Testing
- ALVAC-HIV (vCP2438), Bivalent Subtype C gp120/MF59
- Where
- 14 sites in South Africa
- Volunteers
- 5,404 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cardiovascular Diseases, Cardiovascular Morbidity
Prediction of the Risks of Cardiovascular Mortality
Monitoring risks of cardiovascular diseases in working population (18 - 65 years old) by monitoring their BMI, ankle-brachial index with pulse wave velocity, cholesterol and glycemia.
- Conditions
- Cardiovascular Diseases, Cardiovascular Morbidity, Stroke, Embolism
- Trial name
- NCT06103448
- Testing
- Ankle-brachial index - system 100
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jan Evangelista Purkyne University
Diabetes, Pain Management
CGM as Diagnostic Tool in Observing Steroid-Induced Hyperglycemia
This study is designed to help understand how certain steroid medications affect blood sugar levels in patients undergoing pain management treatments.
- Trial name
- TRC-DX-1 (NCT06628284)
- Testing
- Dexcom G7
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Mahesh Pattabiraman
Healthy Volunteer, HIV Prevention
Evaluation of Single Dosing With Two F/TAF Tablets Among Healthy Volunteers
The goal of this study is to evaluate the pharmacokinetics of a one-time dosing of two F/TAF tablets over a 14-day period.
- Trial name
- DD-PrEP: (NCT07349758)
- Testing
- tenofovir alafenamide [TAF] 50 mg/emtricitabine [FTC] 400mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Weight Loss
Weight Loss and Prevention in Latina Immigrants: Advancing Methods of Community-Based Intervention Delivery
The long-term objective of this study protocol is to develop and test a culturally sensitive, community-based intervention, ESENCIAL Para Vivir (Essential for Life) to promote weight loss and diabetes prevention among overweight…
- Trial name
- NCT02344212
- Testing
- ESENCIAL Para Vivir: a weight loss program for Latinas
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Coronavirus Infection, Disease Prevention
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment
The purpose of this study is to assess the safety and efficiency of an assembled modified mask in protecting health care workers against Coronavirus in case of any personal protective equipment shortage.
- Trial name
- NCT04416919
- Testing
- Assembled mask
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Middle School and High School Students
Impact of an HPV Primary Prevention Intervention on HPV Vaccination Rates Among Adolescents in the AuRA Region.
Human papillomaviruses (HPV) are very common contagious viruses: approximately 70% of men and women will be infected during their lifetime.
- Trial name
- PIMCOP (NCT07414719)
- Testing
- HPV animation
- Where
- France
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Rabies Infection
Safety and Immunogenicity of Two Intradermal Rabies Vaccine Regimens Administered With and Without Human Rabies Immunoglobulin in Subjects ≥ 1 Years of Age
Demonstrate non-inferiority of the immune response between new versus the currently recommended intradermal regimens of rabies vaccine when administered with or without rabies immunoglobulins in healthy subjects ≥ 1 years of age.
- Trial name
- NCT02177032
- Testing
- Rabies vaccine, Rabies vaccines + Rabies immunoglobulins
- Where
- 6 sites in Philippines, Thailand
- Volunteers
- 885 people, healthy volunteers welcome
- Sponsor
- Novartis
Prostate Cancer
Lycopene in Preventing Prostate Cancer in Healthy Participants
RATIONALE: Chemoprevention is the use of certain drugs or substances to keep cancer from forming, growing, or coming back. The use of lycopene, a substance found in tomatoes, may keep prostate cancer from forming.
- Trial name
- NCT00322114
- Testing
- lycopene
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
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