Clinical trials: Pressure Injuries
Spinal Cord Injury, Blood Pressure
Treating Cognitive Deficits in Spinal Cord Injury
Multiple studies in the spinal cord injury (SCI) population have documented deficits in learning and memory (LM) and processing speed (PS) that adversely impact daily life and the ability to benefit from rehabilitation.
- Conditions
- Spinal Cord Injury, Blood Pressure, Cerebral Blood Flow, Cognitive Function
- Trial name
- NCT03037879
- Testing
- SPT, SPT Control, mSMT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Medical Device Related Pressure Ulcer (MDRPU), Pressure Injury
Clinical and Cost-Effectiveness of an Artificial Intelligence -Synthesized Nursing Care Bundle for Preventing Medical Device-Related Pressure Injuries
Medical device-related pressure injuries (MDRPIs) are an important and largely preventable patient safety problem, particularly in intensive care units where the use of medical devices is frequent and prolonged.
- Trial name
- NCT07789613
- Testing
- Control Group, Care Bundle Group
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Koç University
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Abdomenal Wound Trauma
Non-Comparative Study of Open Abdomen That Require the Use of Negative Pressure Wound Therapy (NPWT) for Temporary Abdominal Closure
A study in which subjects with a Grade 1 or Grade 2 open abdomen that require the use of NPWT for temporary abdominal closure. Subjects will use the NPWT system for up to 14 days, with a 21 day post study initiation follow-up…
- Trial name
- NCT03431220
- Testing
- RENASYS® TOUCH Negative Pressure Wound Therapy (NPWT) Device
- Where
- United States
- Sponsor
- Smith & Nephew, Inc.
Neurologic Disorders, Spinal Cord Injury
Reliability and Validity of the PReFS
This study is testing the psychometric properties of a new tool to determine recommendations for pressure relief frequency in wheelchair users.
- Conditions
- Neurologic Disorders, Spinal Cord Injury, Stroke, Traumatic Brain Injury
- Trial name
- PReFS (NCT07280923)
- Testing
- Interview
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Baylor University
Respiratory Insufficiency Syndrome of Newborn, Infant, Premature, Diseases
PEEP and V/Q Mismatch in Premature Infants
Positive end-expiratory pressure (PEEP) is used in premature infants receiving mechanical ventilation to maintain lungs open and facilitate gas exchange.
- Trial name
- NCT03109613
- Testing
- Positive end-expiratory pressure (PEEP)
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Philadelphia
Drowning
Drowning-related Acute Respiratory Failure
The purpose of this study is to assess the Non-Invasive Ventilation-Continuous Positive Airway Pressure efficacy (experimental group) for drowning related Acute Respiratory Failure compared to Oxygen Supply by face mask…
- Trial name
- CPAPDROWNING (NCT06183827)
- Testing
- Emergency Medical Service intervention : Oxygen Supply strategy, Emergency Medical Service intervention : Continuous Positive Airway Pressure strategy
- Where
- 9 sites in France
- Volunteers
- 210 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Head Injury, Intracerebral Hemorrhage
The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients
The purpose of this study is to use transcranial Doppler (TCD) to predict intracranial pressure (ICP) and clinical outcome of neurocritical patients.
- Conditions
- Head Injury, Intracerebral Hemorrhage, Ischemic Stroke, Subarachnoid Hemorrhage
- Trial name
- NCT00886054
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Acute Respiratory Distress Syndrome (ARDS), s100b
A Study of the Determinants of Neurological Outcomes in Patients With Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is characterized by pathological pulmonary edema caused by direct or indirect damage to the alveolar-capillary membrane.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), s100b, Mechanical Power, Ventilator Induced Lung Injury
- Trial name
- NEURDS (NCT07629973)
- Testing
- Blood test scores calculations
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Ankle Injuries, Ankle Injuries and Disorders
The Effect of Taping on Plantar Pressure Distribution in Players With Chronic Ankle Instability
The goal of this study is to investigate whether there exists a difference in baropdometric readings of plantar pressure between individuals with chronic ankle instability and normal health individuals, in addition another goal…
- Conditions
- Ankle Injuries, Ankle Injuries and Disorders, Ankle Sprains
- Trial name
- NCT06499935
- Testing
- Rigid Taping, Kinesio-Taping
- Where
- Lebanon
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
The purpose of this study is to compare two methods of delivering Nasal Continuous Airway Pressure (NCPAP): Biphasic Mode and a continuous mode, to see which is better in getting babies off the ventilator and decreasing lung…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Apnea of Prematurity
- Trial name
- NCT00308789
- Testing
- Biphasic Infant flow NCPAP, CPAP
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Breast Reconstruction
Negative Pressure in PAP Donor Sites
A retrospective chart review will be conducted to identify patients who received breast reconstruction using free profunda artery perforator (PAP) flap by the investigators from January 2015 to August 2021.
- Trial name
- NCT05491473
- Testing
- Closed incisional negative pressure wound therapy (iNPWT) system
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Traumatic Brain Injury
Aerosolized Endotracheal Lidocaine to Avoid Intracranial Pressure Spikes in Patients With Severe Traumatic Brain Injury
The purpose of this study is to evaluate the effectiveness of nebulized lidocaine before Endotracheal suctioning (ETS) compared to instilled lidocaine and the effectiveness of aerosolized lidocaine versus instilled normal saline…
- Trial name
- NCT05058677
- Testing
- aerosolized 2% lidocaine (20mg/ml), instilled 0.9% sodium chloride (NS), instilled 2% lidocaine solution
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs)
Real-World Effectiveness of Amniotic Membrane Allografts Versus Standard Wound Care in DFU, VLU, and PU
This observational study will evaluate the real-world effectiveness of four amniotic membrane-based products (Zenith™, Orion™, SurGraft FT™, Complete ACA™) in addition to standard care, compared with standard care alone.
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
- Trial name
- NCT07223281
- Where
- 4 sites in United States
- Volunteers
- 2,400 people
- Sponsor
- Legacy Medical Consultants
Nursing Education Research, Simulation Based Learning
The Effect Of Low-Fidelity Simulation Education Pressure Injuries
The nursing education curriculum comprises both theoretical and practical courses designed to educate and prepare nursing students for their professional roles, functions, and responsibilities.
- Conditions
- Nursing Education Research, Simulation Based Learning, Pressure Injuries
- Trial name
- NCT07890519
- Testing
- Simulation-Based Training, Traditional Training
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hilal Türkben Polat
Tennis Elbow
Comparative Study Between Different Mobilization Techniques for Patients With Chronic Tennis Elbow
Background: Tennis elbow is a common musculoskeletal disorder affecting the functional activities of daily living through common extensor tendinopathy.
- Trial name
- RCT (NCT06812377)
- Testing
- Maitland joint mbilization, mulligan mobilization, radial nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Spinal Cord Injuries (SCI), Blood Pressure
AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury
The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge.
- Conditions
- Spinal Cord Injuries (SCI), Blood Pressure, Thermoregulation, Perfusion Index
- Trial name
- NCT07699094
- Testing
- Controlled Cool Thermal Challenge (18°C)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Pressure Injury, Injuries
Effect of Different Positioning Before, During and After Surgery on Pressure Injury
Background: Patients undergoing surgery are at risk of developing pressure injuries since they remain in a fixed position on the operating table under anesthesia for a long time.
- Trial name
- NCT05549830
- Testing
- Patient Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Severe Traumatic Brain Injury
Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics
Narrative: Worldwide, traumatic brain injury (TBI) is a leading cause of death and disability among children and adolescents. The Investigators aim to test whether pediatric TBI treatment guided by invasive intracranial pressure…
- Trial name
- BELA TRIPP (NCT05566431)
- Testing
- ICP, CREVICE
- Where
- 11 sites in United States, Colombia and 4 more
- Volunteers
- 428 people
- Sponsor
- University of Washington
Radius Fractures
Referred Pain Areas in Subjects With a Recovered Radius Fracture
The purpose of the present study is to investigate pressure algometry and pressure-induced referred pain areas in pain free individuals with a history of distal radius fracture (fully recovered) compared with age and gender…
- Trial name
- NCT03531801
- Testing
- Pressure algometry and mapping referred pain areas
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad San Jorge