Clinical trials: Presbyopia
Refractive Error
Clinical Assessment of DAILIES TOTAL1® (DT1) Multifocal
The purpose of this study is to evaluate DAILIES TOTAL1® Multifocal (DTl MF) contact lenses in current multifocal contact lens wearers with symptoms of end of day discomfort compared to their habitual multifocal contact lens…
- Trial name
- NCT02871375
- Testing
- Delefilcon A multifocal contact lenses, Habitual multifocal contact lenses
- Volunteers
- 170 people
- Sponsor
- Alcon, a Novartis Company
Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
- Trial name
- NCT05135286
- Testing
- BRIMOCHOL™ PF, Carbachol PF, Vehicle
- Where
- 42 sites in United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Visus Therapeutics
Lens Diseases
Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment…
- Trial name
- NCT07321756
- Testing
- Unilateral Posterior Chamber Implantation of Presbyopia-Correcting IOL, Unilateral Posterior Chamber Implantation of Monofocal IOL
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Presbyopia, Myopia
Intrastromal Correction of Ametropia by a Femtosecond Laser
This study evaluates the intrastromal correction of ametropia with a femtosecond laser made by 20/10 PERFECT VISION. This laser generates a beam of ultrashort, infrared pulses which enables very precise cuts in the cornea.
- Conditions
- Presbyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- ISCAF (NCT00928122)
- Testing
- Intrastromal Correction of Presbyopia, Intrastromal correction of Myopia, Intrastromal Correction of Hyperopia
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- 20/10 Perfect Vision
Presbyopia, Refractive Errors
Apioc Presbyopic Contact Lens
In this study, you will wear an invesetigational contact lens, Apioc-P or Apioc-PT, the way you wear your current contact lenses for approximately one month (no more than 35 days).
- Trial name
- NCT04437732
- Testing
- Apioc-P and Apioc-PT Contact Lens Design
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Cataract Senile, Presbyopia
RayOne EMV Mini-monovision - Efficiency and Safety of 3 Grades of Mini-monovision
Aim:To determine the effectiveness and subjective satisfaction of patients with bilateral cataract surgery and implantation of intraocular lens (IOL) RayOne EMV with enhanced optic, using different degrees of mini-monovision (up…
- Trial name
- EMV (NCT05417633)
- Testing
- intraocular lens - RayOne EMV (Rayner Surgical GmbH,Berlin, Deutschland)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Somich, s.r.o.
Presbyopia
A Clinical Comparison of Two Soft Multifocal Contact Lenses
The study objective was to gather short-term clinical performance data for two soft multifocal contact lenses.
- Trial name
- NCT05794126
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- CooperVision, Inc.
Cataract, Presbyopia
Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients With Presbyopia
This is to evaluate the satisfaction of patient and physician about short-distance, medium-distance, long-distance postoperative vision and eyeglass dependence, glare, and visual acuity after insertion of the TECNIS® Symfony or…
- Trial name
- NCT03501654
- Testing
- TecnisSymfony®
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Presbyopia
Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
This is a one-day, randomized, double-masked, single-center evaluation of the efficacy and safety of PRX-100 ophthalmic solution compared to placebo in 20 subjects (randomized 4:1, PRX-100:placebo) to evaluate the safety of…
- Trial name
- NCT02554396
- Testing
- PRX-100
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- LENZ Therapeutics, Inc
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Cataract, Presbyopia
Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision
In an aging population, cataract and presbyopia become increasingly common. A cataract is the opacification of the natural crystalline lens inside a person's eye, causing reduction of vision.
- Conditions
- Cataract, Presbyopia, Astigmatism
- Trial name
- NCT05506553
- Testing
- Intervention arm - Eyhance Toric II Intraocular Lens, Control Arm - Alcon IQ Toric Intraocular lens
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Presbyopia
A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopic patients with treatments to optimize the ocular surface before corneal inlay surgery.
- Trial name
- NCT03126877
- Testing
- Mitomycin C, Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Whitten Laser Eye
Cataract
Clinical Outcomes Following Implantation of Tecnis Synergy and Symfony Intraocular Lens
Tecnis Symfony Optiblue (Johnson \& Johnson Vision, Santa Ana, CA, Unites States) is a violet light filtering extended depth of focus intraocular lens (IOL) that provides a continuous range of clear vision at far and…
- Trial name
- NCT05541796
- Testing
- Intraocular lens
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- George O. Waring IV
Presbyopia
Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia
The objective of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of AGN-241622 ophthalmic solution for the first time in human participants
- Trial name
- NCT04403763
- Testing
- AGN-241622, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Presbyopia
Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients
The objective of this study is to obtain an additional 36 months of safety and effectiveness data from all subjects who were implanted with the VisAbility™ Micro Insert in the VIS-2014 clinical trial.
- Trial name
- NCT03811249
- Testing
- VisAbility™ Micro Insert
- Where
- 13 sites in United States
- Volunteers
- 287 people
- Sponsor
- VisDura, Inc.
Pupil Constriction
Evaluation of NV701 (Pilocarpine 1.25%) Compared With Vuity (Pilocarpine 1.25%) on Pupil Size in Subjects With Presbyopia
Randomized contralateral eye study to evaluate the effect of one-time dosing of NV701 versus commercially available 1.25% pilocarpine solution on pupil size.
- Trial name
- NCT06783686
- Testing
- NV701, Pilocarpine 1.25% Eye drop
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Novus Vision LLC
Presbyopia
Clinical Assessment of a Multifocal Contact Lens for People Who Use Reading Glasses Only
The purpose of this trial is to evaluate the use of multifocal contact lenses in people who use reading glasses only.
- Trial name
- NCT01268501
- Testing
- Lotrafilcon B multifocal contact lens
- Volunteers
- 103 people
- Sponsor
- CIBA VISION
Presbyopia, Pseudophakia
Synergy Lens Outcomes Evaluation
This is a single visit study to evaluate the visual outcomes and patient satisfaction of patients who were bilaterally implanted with the Tecnis Synergy IOL between June 1 and December 31, 2021 in 2 centers in USA
- Trial name
- NCT05418153
- Testing
- Tecnis Synergy IOL
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Center For Sight
Cataract, Presbyopia
Comparison of Two Aspheric Intraocular Lenses for Micro-monovision
In an aging population, cataract and presbyopia become increasingly common. A cataract develops when the natural crystalline lens inside a person's eye, becomes cloudy over time, causing reduction of vision.
- Conditions
- Cataract, Presbyopia, Pseudophakia
- Trial name
- NCT05531110
- Testing
- Cataract surgery with insertion of Eyhance ICB00, Cataract surgery with insertion of Alcon SN60WF
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Presbyopia Correction
VIS Opti-K Vision Improvement for Presbyopes
The VIS Opti-K device and procedure were used to provide vision improvement to patients with presbyopia.
- Trial name
- VIS Opti-K 002 (NCT06702020)
- Volunteers
- 135 people
- Sponsor
- VIS, Inc.