Clinical trials: Premenstrual Dysphoric Disorder (PMDD)
Epilepsy
Premenstrual Dysphoric Disorder and Antiepileptic Drugs
This study is being done to determine if there are differences in mood during the menstrual cycle among women with epilepsy who take various different antiepileptic drugs and women without epilepsy.
- Trial name
- NCT00612235
- Testing
- Lamotrigine, Levetiracetam, Carbamazepine
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
PMDD, Premenstrual Dysphoric Disorder (PMDD)
Identification and Validation of Epigenetic Biomarkers of PMDD
This research is being done to examine epigenetic markers and mood changes across the menstrual cycle, particularly in premenstrual dysphoric disorder (PMDD).
- Conditions
- PMDD, Premenstrual Dysphoric Disorder (PMDD), Premenstrual Syndrome-PMS, Premenstrual Syndrome
- Trial name
- BIO (NCT06771583)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Premenstrual Dysphoric Disorder
Deep Transcranial Magnetic Stimulation (dTMS) for the Treatment of Premenstrual Dysphoric Disorder (PMDD)
Premenstrual dysphoric disorder (PMDD) is a hormone-dependent mental condition that causes significant suffering in 5% of women of reproductive age worldwide.
- Trial name
- NCT02448836
- Testing
- dTMS H-coil system:magstim stimulator rapid2,BrainswayH1coil
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Premenstrual Dysphoric Disorder
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age.
- Trial name
- Premensis-s (NCT06496139)
- Testing
- Therapist-guided internet-delivered cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Uppsala University
Premenstrual Dysphoric Disorder
Premenstrual Hormonal and Affective State Evaluation (PHASE) Project
PHASE is designed to evaluate neuroactive hormone trajectories across the menstrual cycle and endocrine, autonomic, and subjective responses to psychosocial stress in women suffering from severe PMS (i.e., premenstrual dysphoric…
- Trial name
- PHASE Project (NCT03862469)
- Testing
- Individualized laboratory test
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Premenstrual Dysphoric Disorder
Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder
The objective of this study is to evaluate the effectiveness and safety in double-blind, randomized, placebo-controlled clinical trials of self administered PH80 intranasal spray for the acute management of cycle related symptoms…
- Trial name
- PH80-PMD (NCT01217775)
- Testing
- PH80
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Contraception, Premenstrual Syndrome
Regulatory Post Marketing Surveillance Study on YAZ
The objective of this Post Marketing Surveillance (PMS) is to gain information about safety and efficacy in real practice.
- Conditions
- Contraception, Premenstrual Syndrome, Acne
- Trial name
- NCT00998257
- Testing
- EE20/DRSP (YAZ, BAY86-5300)
- Where
- South Korea
- Volunteers
- 770 people
- Sponsor
- Bayer
Premenstrual Dysphoric Disorder
Combined Effect of Tryptophan Rich Diet and Acupuncture on Depression Related to Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) affecting up to 8% of reproductive age women.
- Trial name
- NCT05813366
- Testing
- Acupuncture, Tryptophan-Rich Diet, Vitamin B6 Supplementation
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Menstruation Disturbances, Premenstrual Syndrome
Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder
The purpose of this study is to determine whether levonorgestrel (LNG)/ethinyl estradiol (EE) is effective in treating the symptoms of severe premenstrual syndrome (PMS).
- Trial name
- NCT00128934
- Testing
- levonorgestrel/ethinyl estradiol
- Where
- 83 sites in United States, Canada
- Volunteers
- 744 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Dysmenorrhea Primary, Dysmenorrhea
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25
85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative…
- Conditions
- Dysmenorrhea Primary, Dysmenorrhea, Menstrual Discomfort, Menstrual Problem
- Trial name
- NUTRITION; GYN (NCT06227676)
- Testing
- Cramp Bites by Aunt Flo's Kitchen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cornell University
Premenstrual Syndrome
Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder
This study will determine whether characteristics of women with Premenstrual Syndrome influence response to treatment with serotonin reuptake inhibitors and whether SRIs can alleviate premenstrual symptoms.
- Trial name
- NCT00048854
- Testing
- Sertraline, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Yale University
Premenstrual Syndrome
Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder
This study will evaluate the effectiveness of flutamide in reducing symptoms of premenstrual dysphoric disorder.
- Trial name
- NCT00611923
- Testing
- Flutamide
- Volunteers
- 115 people
- Sponsor
- Weill Medical College of Cornell University
Premenstrual Dysphoric Disorder ( PMDD)
To Establish Whether Individuals With Premenstrual Dysphoric Disorder (PMDD) Demonstrate a Different Luteal-phase Sex Hormone Profile and Ratio Compared With Asymptomatic Controls.
The aim of this project is to compare the ovarian hormone levels 7 days after ovulation and progesterone:oestradiol ratios between PMDD individuals and a control cohort (case control study).
- Trial name
- NCT07686718
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Premenstrual Disorder, Premenstrual Dysphoric Disorder
Pilot Study of the 'Thriving With PMDs' Program
This study is testing a self-help mental health program that was designed to help people cope with the challenges of living with a premenstrual disorder.
- Trial name
- NCT06648382
- Testing
- Self-directed psychotherapy program for premenstrual disorders
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Regina
Premenstrual Dysphoric Disorder, Premenstrual Syndrome
The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder
The purpose of the study proposed is to investigate the role of neurosteroids and GABA in the pathophysiology and treatment of premenstrual dysphoric disorder (PMDD) by 1) measuring cortical gama-aminobutyric acid levels (GABA…
- Trial name
- NCT00678574
- Testing
- fluoxetine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression, Major Depressive Disorder
Single Session of tACS in a Depressive Episode
Purpose: Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on healthy participants and participants with mood disorders.
- Conditions
- Depression, Major Depressive Disorder, Premenstrual Dysphoric Disorder, Depressive Episode
- Trial name
- SSDE (NCT03449979)
- Testing
- XCSITE100 Stimulator tACS
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders
The purpose of this study is to assess a novel nutritional supplement developed for prenatal health and mood benefits, and to determine whether there is preliminary evidence for efficacy in Menstrual Related Mood Disorders…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Premenstrual Tension, Menstrual Related Mood Disorder
- Trial name
- NCT04123483
- Testing
- EnBrace HR Softgel
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Premenstrual Disorder
The Effect of Progressive Muscle Relaxation Exercises on Premenstrual Syndrome, Anxiety, and Tendency to Violence in Young Women
This study results will provide evidence on the effectiveness of Progressive Muscle Relaxation Exercises (PMRE) as a complementary method in improving Premenstrual Syndrome (PMS), an important women's health issue.
- Trial name
- NCT06909955
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Premenstrual Dysphoric Disorder, Bipolar Disorder
Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder
This study is a pilot, randomized, placebo-controlled trial evaluating the treatment of Premenstrual Dysphoric Disorder comorbid with Bipolar Disorder using combined oral contraceptives.
- Trial name
- NCT05098574
- Testing
- Yaz
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Premenstrual Syndrome, Menstruation Disturbances
Study Evaluating Combination of Levonorgestrel and Ethinyl Estradiol in Pre-Menstrual Dysphoric Disorder
The purpose of this study is to determine whether Levonorgestrel/Ethinyl Estradiol (LNG/EE) is effective in treating the symptoms of severe Premenstrual Dysphoric Disorder.
- Trial name
- NCT00195559
- Testing
- Levonorgestrel/Ethinyl Estradiol
- Where
- 51 sites in Argentina, Brazil and 10 more
- Volunteers
- 526 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer