Clinical trials: Premedication
Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis)
Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy
The current study is looked for the comparison between nebulized lidocaine and ketamine, nebulized lidocaine, and usual lidocaine spray in the oral and nasal cavities before flexible bronchoscopy.
- Conditions
- Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis), Premedication
- Trial name
- NCT07743333
- Testing
- Nebulized lidocaine and ketamine, Nebulized Lidocaine, Lidocaine spray (2%)
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Alexandria University
Pediatric Anesthesia, Premedication
Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery
This prospective, three-arm study aims to evaluate the effects of different oral premedication regimens on venipuncture tolerance in pediatric patients undergoing ambulatory surgery.
- Trial name
- NCT07410078
- Testing
- Oral Midazolam Premedication, Oral Midazolam plus Ibuprofen Premedication, Oral Midazolam plus Ketamine Premedication
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Anxiety, Premedication
Effect of Virtual Reality on the Need of Premedication Before Surgery
This study will assess, on patients requesting a pharmacological premedication in the preoperative period, if virtual reality reality could reduce the request of pharmacological premedication while maintaining a good level of…
- Conditions
- Anxiety, Premedication, Surgery, Virtual Reality
- Trial name
- NCT07450456
- Testing
- Virtual Reality
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Allergic Reaction to Contrast Media, Hypersensitivity Reaction
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 Study
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 is a prospective, parallel, two-arm, non-inferiority, randomized controlled trial evaluating the safety of a 1-hour (intervention) versus a 4-hour (standard regimen)…
- Conditions
- Allergic Reaction to Contrast Media, Hypersensitivity Reaction, Computed Tomography, Premedication
- Trial name
- PAGE1 (NCT07268248)
- Testing
- IV glucocorticoid and antihistamine, IV glucocorticoid and antihistamine (standard of care)
- Volunteers
- 540 people
- Sponsor
- Paul Peng, MD PhD MSCR
Emergence Delirium, Anesthesia, Child
Melatonin vs Midazolam in Children Undergoing Tonsillectomy
Used as a premedication to decrease anxiety (Caumo et al., 2007). Midazolam, though has several drawbacks (McCann and Kain, 2001). Hence, an alternative premedication to midazolam will definitely have a widespread appeal.
- Conditions
- Emergence Delirium, Anesthesia, Child, Anxiety, Midazolam Premedication
- Trial name
- NCT07336095
- Testing
- Melatonin group, Midazolam group, Control group
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Anxiolytic Effect, Virtual Reality Immersion
Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery
The aim is to investigate the anxiolytic effect, and hemodynamic stability of using virtual reality immersion in adult patients undergoing Dacryocystorhinostomy (DCR) operation under general anesthesia and to compare its effect…
- Conditions
- Anxiolytic Effect, Virtual Reality Immersion, Midazolam, Premedication
- Trial name
- NCT07050095
- Testing
- Virtual Reality Group, Midazolam Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Premedication
Premedication on Post-endodontic Pain
The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT06671743
- Testing
- Root canal treatment
- Where
- United Arab Emirates
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Autism Spectrum Disorder, Premedication
EMERGENCE AGITATION After Premedication IN PAEDIATRIC MAGNETIC RESONANCE IMAGING: A RETROSPECTIVE COHORT STUDY
The aim of this study was to assess the anxiolytic and sedative effect of OZALIN® / OZASED® (ADV6209) 0,25mg/Kg in children undergoing magnetic resonance imaging (MRI) under inhalational anesthesia.
- Conditions
- Autism Spectrum Disorder, Premedication, Brain Neoplasms, Brain Pathology
- Trial name
- premidazolam (NCT05946928)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Functional Endoscopic Sinus Surgery, Premedication
Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS
Intranasal dexmedetomidine provided good pharmacokinetic profile. However, intravenous dexmedetomidine have been used in functional endoscopic sinus surgery for several outcomes, there is lack in studies that had compared the…
- Conditions
- Functional Endoscopic Sinus Surgery, Premedication, Analgesia
- Trial name
- NCT05604599
- Testing
- Intranasal dexmedetomidine, Intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Premedication
Oral Dexmedetomidine vs Midazoam For Premedication
The aim of this study was to compare the effect of 2 µg/kg of oral dexmedetomidine (DEX) and 0.5 mg/kg dormicum as premedication among children undergoing dental procedures.
- Trial name
- NCT03357718
- Testing
- Precedex, Midazolam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Premedication, Endotracheal Intubation
Cerebral NIRS Profiles During Premedication for Neonatal Intubation
Observational ancillary study of the PRETTINEO study (ClinicalTrials.gov Identifier: NCT01490580) which is a multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil"…
- Conditions
- Premedication, Endotracheal Intubation, Cerebral Hypoperfusion
- Trial name
- NCT02700893
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 2 sites in France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Coronary Angiography, Sedative Premedication
Sedative Premedication in Coronary Angiography
Evaluation of the possible positive effect of sedative premedication prior to coronary angiography in regards to pain and anxiety.
- Trial name
- NCT03576456
- Testing
- Alprazolam 0.5 mg
- Where
- Belgium
- Volunteers
- 264 people
- Sponsor
- Universitair Ziekenhuis Brussel
Anxiety, Premedication
Preoperative Anxiety Level, Premedications and General Anaesthetic Proceedings
Although it seems obvious that the high level of preoperative anxiety may affect intraoperative anaesthetic requirements and recovery adversely, there are several contradictory studies about this subject.
- Conditions
- Anxiety, Premedication, General Anaesthetic
- Trial name
- NCT03603873
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- CHU de Reims
Midazolam Premedication, Anxiety Preoperative
Assessing the Effectiveness of Midazolam Premedication
Pre-anesthetic dosing of midazolam is commonly used in many hospitals for the induction of anesthesia, but the effect is still controversial.
- Conditions
- Midazolam Premedication, Anxiety Preoperative, Premedication
- Trial name
- NCT03325335
- Testing
- Midazolam premedication, Remifentanil infusion, Propofol infusion
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Pusan National University Hospital
Premedication
Dexmedetomidine Premedication in Children
The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.
- Trial name
- NCT03174678
- Testing
- Dexmedetomidine, apple juice
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Premedication, Oculocardiac Reflex
Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients
The aim of this study is using intranasal dexmedetomidine versus intranasal midazolam-ketamine combination for premedication and preventing the oculocardiac reflex of pediatric patients undergoing strabismus surgery.
- Trial name
- NCT02072083
- Testing
- Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Premedication, Anaesthesia
Melatonin Premedication in Children Undergoing Surgery
Melatonin has been proposed as alternative to midazolam as a premedication in procedures preceding anaesthesia induction. The objective of this prospective, randomized, double-blind study is to investigate the possible effect of…
- Trial name
- NCT02265822
- Testing
- melatonin in children premedication, midazolam in children premedication
- Volunteers
- 92 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"