Clinical trials: Prehabilitation
Frailty, Functional Recovery
Multi-Component Prehabilitation for Major Elective Surgery
The purpose of this pilot study is to assess the feasibility of delivering a multicomponent prehabilitation and measuring patient-centered outcomes in older adults undergoing major surgery.
- Conditions
- Frailty, Functional Recovery, Prehabilitation
- Trial name
- NCT05752474
- Testing
- Exercise, Nutrition, Meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Cancer, Frailty
Patient-centered REhabilitation Program to Advance REcovery
The goal of this clinical trial is to learn whether an app-based, patient-centered prehabilitation program improves preoperative functional capacity in adults scheduled for elective cancer surgery.
- Conditions
- Cancer, Frailty, Prehabilitation
- Trial name
- PREPARE-CAN (NCT07189000)
- Testing
- App-based prehabilitation program, Usual care (ERAS-standard perioperative care)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Korea University Anam Hospital
Cardiac Surgery, Prehabilitation
Prehabilitation Program for Patients Awaiting Elective Heart Surgery at Increased Risk of Postoperative Complications: Feasibility and Potential Clinical Outcomes
The goal of this study is to learn if an exercise-based prehabilitation program can help people who are waiting for heart surgery and are at higher risk of complications recover better.
- Conditions
- Cardiac Surgery, Prehabilitation, Postoperative Complications
- Trial name
- PRÉAD-CARDIAQU (NCT07144722)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Montreal Heart Institute
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer.
- Conditions
- Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, Prehabilitation
- Trial name
- NCT05576766
- Testing
- Routine care, ERAS management pathway
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking University First Hospital
Hematological Malignancy, Prehabilitation
Investigation of the Effects of Prehabilitation Education Delivered Through a Mobile Compatible Website on Quality of Life and Symptoms in Patients Undergoing Hematopoietic Stem Cell Transplantation
Aim of the Study: The aim of this study is to examine the effect of prehabilitation education delivered via a mobile-compatible website on the quality of life and symptom evaluation of patients undergoing hematopoietic stem cell…
- Conditions
- Hematological Malignancy, Prehabilitation, Patient Education
- Trial name
- NCT07066592
- Testing
- Prehabilitation education provided via mobile compatible website
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Ischaemic Heart Disease, Prehabilitation
CABGpreHAB - a Feasibility Study Protocol
Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity.
- Conditions
- Ischaemic Heart Disease, Prehabilitation, Coronary Artery Bypass, Feasibility Studies
- Trial name
- NCT07035171
- Testing
- Multimodal prehabilitation intervention, Control (Standard treatment)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Frailty in Adult Surgery, Frail Elderly Syndrome
Patient's Database: Prepare for Your Surgery Program
Frailty is a multidimensional syndrome that predominantly affects older people and people with long-term treatments such as cancer and chronic pain.
- Conditions
- Frailty in Adult Surgery, Frail Elderly Syndrome, Database, Perioperative Care
- Trial name
- NCT06857981
- Testing
- Clinical data collection
- Where
- 2 sites in Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Prehabilitation, Malnutrition
Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Despite multi-modal prehabilitation (nutrition, exercise, and psychosocial interventions), 60% of older elective colorectal cancer surgery patients with poor physical function were unable to reach a minimum preoperative 400m…
- Conditions
- Prehabilitation, Malnutrition, Physical Functional Performance
- Trial name
- NCT05999370
- Testing
- Nutrition, Exercise
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University
Anemia, Anemia (Iron-Loading)
Evaluate the Outcomes of Ferric Carboxymaltose in Patients With Perioperative Anemia
The prevalence of preoperative anaemia in patients undergoing major surgery is approximately 30%, and is independently associated with higher mortality, a higher rate of postoperative complications, and a greater probability of…
- Conditions
- Anemia, Anemia (Iron-Loading), Perioperative Bleeding, Infection Prevention
- Trial name
- NCT06948864
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Hospital Universitario Infanta Cristina
Ovarian Cancer, Neoadjuvant Chemotherapy
Prehabilitation During the Neoadjuvant Window of Opportunity in Older Women With Ovarian Cancer
The purpose of this study is to test the effectiveness of a home-based, patient-tailored intervention, FIT4SURGERY, to promote physical activity among women with ovarian cancer undergoing neoadjuvant chemotherapy.
- Conditions
- Ovarian Cancer, Neoadjuvant Chemotherapy, Prehabilitation
- Trial name
- FIT4SURGERY (NCT05092763)
- Testing
- FIT4SURGERY, Healthy Lifestyle Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Prehabilitation
Cognitive and Physical Optimization in Prevention of Postoperative Cognitive Deficit in Elderly With Lung Resection
Postoperative cognitive deficit and its connection with surgery and general anesthesia were first mentioned in the literature in 1955 by Bradford.
- Trial name
- COGNITION (NCT06339268)
- Testing
- Cognitive training, CogniFit App
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Military Medical Academy, Belgrade, Serbia
Colon Cancer, Prehabilitation
Multimodal Prehabilitation in Colorectal Cancer Patients
Postoperative complications can occur in up to 50% of individuals undergoing colorectal resection and are associated with poor prognosis, increased costs, and lower health-related quality of life.
- Trial name
- NCT06443203
- Testing
- Trimodal prehabilitation
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- University Hospital of Ferrara
Obesity and Overweight, Bariatric Surgery
Physical Exercise Prehabilitation Program in MEtabolic SuRgery
The goal of this clinical trial is to learn if an exercise program before bariatric surgery works to treat obesity, could improve physical condition and weight loss before bariatric surgery and induce a lifestyle behavior change.
- Conditions
- Obesity and Overweight, Bariatric Surgery, Prehabilitation, Exercise
- Trial name
- PEPPER (NCT06889207)
- Testing
- Physical exercise prehabilitation
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Flevoziekenhuis
Abdominal Aortic Aneurysm, Prehabilitation
Virtual Prehabilitation for Patients Undergoing Abdominal Aortic Aneurysm Repair
The time between diagnosis and operative intervention represents an untapped opportunity to optimize patient readiness for surgery and augment their function prior to undergoing a physiological stress, rather than purely…
- Conditions
- Abdominal Aortic Aneurysm, Prehabilitation, AAA - Abdominal Aortic Aneurysm
- Trial name
- VPAR (NCT06830967)
- Testing
- Prehabilitation, Exercise therapy, Smoking cessation counselling
- Volunteers
- 20 people
- Sponsor
- Nova Scotia Health Authority
Prehabilitation, Cancer of Colon
Abdominopelvic Cancer Prehabilitation
The main objective of this research is to determine the effectiveness of a Prehabilitation consultation in self-care and physical exercise aimed at patients diagnosed with abdominopelvic cancer with initial surgical indication as…
- Conditions
- Prehabilitation, Cancer of Colon, Cancer of Rectum, Cancer, Ovarian
- Trial name
- NCT05887531
- Testing
- Prehabilitation
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universitat Jaume I
Advanced Hepatocellular Carcinoma (HCC), Prehabilitation
Effect of Prehabilitation During the Conversion Therapy on Postoperative Outcomes in Unresectable Hepatocellular Carcinoma
This is a prospective, randomised controlled clinical trial to study the impact of prehabilitation on postoperative complications, physical function, quality of life, and short-term survival outcomes in patients with unresectable…
- Trial name
- NCT06749678
- Testing
- Prehabilitation, Routine nursing measures
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Prehabilitation, Kidney Transplant Candidates
PREhabilitation of Candidates for REnal Transplantation
In this study a personalized, multi modal prehabilitation intervention will be offered to n = 64 patients on the kidney transplant waiting-list. The control group (n = 64) will receive care as usual.
- Conditions
- Prehabilitation, Kidney Transplant Candidates, Frailty
- Trial name
- PreCareTx (NCT05489432)
- Testing
- Exercise
- Where
- Netherlands
- Volunteers
- 128 people
- Sponsor
- University Medical Center Groningen
Lumbar Spinal Stenosis, Prehabilitation
Feasibility of Prehab for Lumbar Spinal Stenosis
The literature has shown evidence of the effectiveness of prehabilitation programs on post-operative recovery for musculoskeletal conditions; however, evidence for prehabilitation for lumbar spinal stenosis (LSS) is limited.
- Trial name
- NCT05073081
- Testing
- Prehab for LSS, Usual Care
- Where
- 4 sites in Canada
- Volunteers
- 37 people
- Sponsor
- McMaster University
Prehabilitation
PREPARE-M 2024 Undergoing Major Surgery: a Pilot Interventional
Study plan to conduct a pilot interventional study to evaluate the impact of a prehabilitation program on physical function and clinical outcomes.
- Trial name
- NCT06620588
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital