Clinical trials: Pregnancy Trimester, First
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Missed Abortion, Early Pregnancy Loss
GPT-Based Digital Assistant Support During Treatment for Induced Abortion or Missed Abortion
We have developed a digital assistant based on GPT (Generative Pre-trained Transformer) technology, trained specifically to provide empathetic, medically accurate, and guideline-based responses in Hebrew, tailored to the clinical…
- Conditions
- Missed Abortion, Early Pregnancy Loss, Abortion in First Trimester, Abortion, Medical
- Trial name
- NCT07856940
- Testing
- GPT-Based Digital Assistant
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Pregnancy Trimester, First, Anxiety
Addressing Pregnant Women's First Trimester Worries and Information Needs With mHealth Solutions
The first 12 weeks of pregnancy, known as the first trimester, can be one of the most worrying times for women. (Where this lay summary refers to women, it should be taken to include people who do not identify as women but who…
- Conditions
- Pregnancy Trimester, First, Anxiety, Worries, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07114471
- Where
- United Kingdom
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Early Pregnancy Loss, Miscarriage in First Trimester
Letrozole and Misoprostol for Early Pregnancy Loss Management
A pilot cohort study to preliminarily investigate the efficacy of pretreatment with letrozole 10 mg daily for three consecutive days followed by treatment with misoprostol 800 mcg vaginally for medical management of early…
- Conditions
- Early Pregnancy Loss, Miscarriage in First Trimester, Miscarriage
- Trial name
- LeMi (NCT06452719)
- Testing
- Letrozole, Misoprostol
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pennsylvania
Miscarriage, Pregnancy Loss
Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage
The ASPIR study aims to evaluate the cost-utility of outpatient manual vacuum aspiration compared with operating room electric aspiration for the management of first-trimester miscarriage.
- Conditions
- Miscarriage, Pregnancy Loss, First Trimester Pregnancy
- Trial name
- ASPIR (NCT07732231)
- Testing
- Manual vacuum aspiration (MVA), Electric aspiration (EA)
- Where
- France
- Volunteers
- 860 people
- Sponsor
- Nantes University Hospital
Increased Nuchal Translucency in the First Trimester of Pregnancy
Metatranscriptomic Next Generation Sequencing in First Trimester Trophoblast With Increased Fetal Nuchal Translucency (METAHCN)
The study is based on the hypothesis that increased nuchal translucency may be associated with a materno fetal infection and that the pathogen responsible for this infection could be identify with metatranscriptomic…
- Trial name
- METAHCN (NCT05388968)
- Testing
- Metatranscriptomic, Specific microbiologic diagnosis
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Insomnia, Pregnancy, First Trimester
Study for Pregnant Women With Insomnia Using Sleep Inducing Digital Sound Application
This study aims to evaluate the safety and efficacy of sleep inducing digital sound application on pregnant women in their 1st and 2nd trimester with insomnia
- Conditions
- Insomnia, Pregnancy, First Trimester, Pregnancy, Second Trimester
- Trial name
- NCT07266415
- Testing
- Sleep inducing digital sound application, Provides meaningless sound in application, Provides Sleep hygiene education text in application
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Bundang Hospital
To Validate the Clinical Performance of AI/ML Technologies in First-trimester Pregnant Participants, First Trimester Pregnancy
Clinical Performance Evaluation of the Artificial Intelligence (AI)/ Machine Learning (ML) Technologies Utilized by the Origin Medical EXAM ASSISTANT
A multicenter study will be conducted to assess the role of the AI/ML technologies of Origin Medical EXAM ASSISTANT (OMEA) in interpreting first-trimester fetal ultrasound examinations (11 weeks 0 days - 13 weeks 6 days).
- Trial name
- NCT06952439
- Testing
- Images and cines captured through the capture card (ICC)
- Where
- 15 sites in United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Origin Medical Systems, Inc.
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Excessive Weight Gain in Pregnancy, First Trimester, Excessive Weight Gain in Pregnancy With Baby Delivered
Early Prevention of Excessive Gestational Weight Gain Using Lifestyle Change
Nutrition and exercise behaviour change programs can prevent excessive gestational weight gain (EGWG). The Nutrition and Exercise Lifestyle Intervention Program (NELIP) is a previously published two-behaviour change program which…
- Conditions
- Excessive Weight Gain in Pregnancy, First Trimester, Excessive Weight Gain in Pregnancy With Baby Delivered, Birth Weight
- Trial name
- NELIP (NCT02804061)
- Testing
- NELIP
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy
Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy
Glucose intolerance is the commonest medical disorder complicating pregnancy. Hyperglycemia increases the risk of delivering a large for gestational age newborn (LGA) and related complications such as operative delivery, birth…
- Trial name
- NCT06064552
- Testing
- blood sugar
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pregnancy Termination in First Trimester
Patient Preferences in Anesthesia for Abortion Care
This study will use semi-structured interviews with participants in a prospective cohort study to explore women's experiences of pain and preferences in pain management during first trimester surgical abortion to create a more…
- Trial name
- PAC (NCT03030443)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
First Trimester Pregnancy
Comparative Study of Learning Curve for First Trimester Fetal Anomaly Scan
Ultrasound scans during first trimester are more difficult than routine mid-trimester ultrasound scans. Practice guidelines for first trimester fetal ultrasound scans have been provided by the International Society of Ultrasound…
- Trial name
- NCT04707456
- Testing
- Training operator
- Where
- Thailand
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pregnancy Trimester, First, Abortion, Threatened
Thromboelastometry Prediction Utility for Risk of Abortion
This study will use thromboelastometry in ED patients with vaginal bleeding, as well as healthy pregnant controls, to determine if abnormal results are associated with the presence of vaginal bleeding as well as later…
- Trial name
- TEMPURA (NCT03548701)
- Testing
- Thromboelastometry testing
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Echocardiography, Pregnancy Related Conditions, Unspecified, First Trimester
Echocardiographic Assessment of Ventricular Strain During a Healthy Pregnancy in the First, Second, and Third Trimester.
Pregnancy is a physiological situation that produces transient preload and afterload changes. The heart is subjected to reversible morphological remodelings and hemodynamic and functional adaptations.
- Conditions
- Echocardiography, Pregnancy Related Conditions, Unspecified, First Trimester, Pregnancy Related Conditions, Unspecified, Second Trimester, Pregnancy Related Conditions, Unspecified, Third Trimester
- Trial name
- VStrain123P (NCT04395014)
- Testing
- 2D Echocardiography
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Miguel Ayala León
First Trimester Bleeding, Pregnancy
Early Pregnancy Evaluation by Three-Dimensional Ultrasound
Early pregnancy is associated with numerous physiologic alterations - many of which are required to establish normal pregnancy outcome.
- Trial name
- NCT00342290
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
First-trimester Pregnancy
Abortions at Strasbourg University Hospitals
The number of abortions in France and Strasbourg has been stable for several years. In 2017, 1847 were performed in the Gynecology-Obstetrics Department for 6146 deliveries (23% of all pregnancies).
- Trial name
- NCT04101175
- Testing
- Evaluation of the procedure of abortion
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Pregnancy Trimester, First, Pregnancy Trimester, Second
Clinical Trial to Assess the Influence of Gestational Stage and Maternal Age on Arterial Stiffness of the Mother
This is a single-centre, open, parallel-group study with three age groups; no study medication or intervention will be provided. This is a longitudinal follow-up of physiological parameters.
- Conditions
- Pregnancy Trimester, First, Pregnancy Trimester, Second, Pregnancy Trimester, Third
- Trial name
- NCT00180219
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Subchorionic Hematoma in the First Trimester Pregnancy, Miscarriage
Vaginal Administration of ALA vs Progesterone for the Subchorionic Hematoma Treatment
The aim of this study was to compare the therapeutic efficacy of lipoic acid versus progesterone by vaginal administration on subchorionic hematoma resorption in women at the first trimester of pregnancy with threatened…
- Trial name
- NCT02601898
- Testing
- Lipoic acid, Progesterone
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda USL Ferrara
First Trimester Pregnancy, Surgical Termination of Pregnancy
Misoprostol for Cervical Priming Prior to Vacuum Aspiration
Despite of the widespread use, and extensive studies, the optimal route of administration of misoprostol before surgical abortion remains to be defined.
- Trial name
- NCT01933360
- Testing
- Misoprostol sublingual, 1h, Misoprostol sublingual, 3h, Misoprostol vaginal, 1h
- Where
- Sweden
- Volunteers
- 184 people
- Sponsor
- Karolinska Institutet