Clinical trials: Preeclampsia Mild
Preeclampsia, Preeclampsia Severe
Preeclampsia Educational Program Study (PrEPS)
Preeclampsia complicates approximately 8% of all pregnancies. A critical factor of outpatient monitoring is patient education; specifically, education regarding nature of the disease, ongoing short- and long-term risks, and…
- Conditions
- Preeclampsia, Preeclampsia Severe, Preeclampsia Mild, Preeclampsia Postpartum
- Trial name
- PrEPS (NCT06373367)
- Testing
- Illustration based application, Text based application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- MemorialCare Health System
Inflammatory Markers, Preeclampsia Severe
Assessment of Maternal and Fetal Serum Biomarkers in Women With Pre-eclampsia
The findings of markers of placental dysfunction in women with preeclampsia may suggest that these biomarkers may be useful tools for early detection of preeclampsia
- Conditions
- Inflammatory Markers, Preeclampsia Severe, Preeclampsia Mild, Umbilical Cord Issue
- Trial name
- NCT06712550
- Where
- Iraq
- Volunteers
- 204 people
- Sponsor
- SHAHLA KAREEM ALALAF
Preeclampsia (PE), Hypertension ,Pregnancy
Dipyridamole for Early-Onset Preeclampsia: A Pilot Study of Feasibility, Pharmacokinetics, and Biological Effects
Early-onset preeclampsia (PE), defined as preeclampsia presenting before 34 weeks of gestation, is a severe placental disorder associated with significant maternal and perinatal morbidity.
- Trial name
- NCT07738562
- Testing
- Dipyridamole 75 MG
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Hadassah Medical Organization
Hypertension, Pregnancy-Induced, Pre-Eclampsia
Early Vascular Adjustments During Hypertensive Pregnancy
Paradoxical fetal and maternal results of studies have led to inconsistent use of antihypertensive drugs or no treatment at all in mild to moderate gestational hypertension in the Netherlands.
- Trial name
- EVA (NCT02531490)
- Testing
- Labetalol, Nifedipine, Methyldopa
- Where
- Netherlands
- Volunteers
- 368 people
- Sponsor
- Maastricht University Medical Center
Gestational Hypertension, Mild Pre-eclampsia
Labor Characteristics and Outcomes in Women With Gestational Hypertension or Preeclampsia Who Underwent Labor Induction
Comparison of Labor Characteristics and Maternal-Neonatal Outcomes in Induced Labor Between Women with Gestational Hypertension/Mild Preeclampsia and Normotensive Controls
- Trial name
- NCT06907576
- Where
- China
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Preeclampsia Severe or Mild, Cardiac Complication
Persistent Postpartum Cardiovascular Dysfunction in Patients With Preeclampsia
The investigators plan to enroll women with PE prospectively to evaluate incremental cardiovascular risk in those who have PE with severe features. This study includes detailed echocardiographic evaluation at several time points.
- Trial name
- ECHO (NCT04063397)
- Testing
- Echocardiogram, Blood draw
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pre-Eclampsia; Mild
Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
Mild pre-eclampsia represents 75% of cases with pre-eclampsia, possible progression to severe pre-eclampsia makes mild pre-eclampsia a serious problem that requires attention.
- Trial name
- NCT03262961
- Testing
- Sildenafil 20 MG
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Pregnant Women With Mild Preeclampsia
Effect of Methyldopa on Uterine Artery Diameter in Pregnant Women With Mild Preeclampsia
The present study examined the effects of Methyldopa on uterine artery diameter, uterine artery blood flow, umbilical artery and fetal middle-cerebral artery in patients with Preeclampsia, using Doppler ultrasound.
- Trial name
- NCT01674127
- Testing
- Methyldopa
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Pre-Eclampsia; Mild, Gestational Hypertension
Effect of RIC on BP and Inflammatory Response in Women With Pre-eclampsia
The aim of this pilot cohort study is to investigate whether treatment with remote ischemic conditioning (RIC) has a beneficial effect on blood pressure as well as the immune system in pregnant women with newly diagnosed…
- Trial name
- NCT03323762
- Testing
- Remote Ischaemic Conditioning (RIC)
- Where
- 3 sites in Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Mild Pre-eclampsia
Effect of Foot Reflexology on Preeclampsia
the aim of this study to investigate the effect of foot reflexology on mild preeclampsia during pregnancy
- Trial name
- NCT05888896
- Testing
- methyldopa tablets 250mg, methyldopa tablets 250mg + foot reflexology
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Preeclampsia, Preeclampsia Postpartum
Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound
This study explores a novel approach to improving care for postpartum patients with preeclampsia, a pregnancy-related condition characterized by high blood pressure, protein in the urine, and organ dysfunction.
- Conditions
- Preeclampsia, Preeclampsia Postpartum, Preeclampsia Severe or Mild
- Trial name
- PPPOCUS (NCT07167862)
- Testing
- Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of California, Irvine
Preeclampsia and Eclampsia, Preeclampsia Severe
Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification
The purpose of this study is to 1. Identify a cut-off for the ratio of the serum proteins soluble FMS-like Tyrosine Kinase 1 (sFLT-1) and placental growth factor (PlGF) that identifies women will who develop preeclampsia with…
- Conditions
- Preeclampsia and Eclampsia, Preeclampsia Severe, Gestational Hypertension, Chronic Hypertension in Obstetric Context
- Trial name
- PRAECIS (NCT03815110)
- Where
- 18 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Cedars-Sinai Medical Center
Preeclampsia
Mild Preeclampsia Near Term: Deliver or Deliberate?
Preeclampsia with new-onset hypertension and proteinuria is a pregnancy-specific disease that affects 5-7% of gestations usually after the 20th week.
- Trial name
- NCT00789919
- Testing
- Delivery of infant
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- University of Mississippi Medical Center
Pre-Eclampsia
Peri-operative Dexmedetomidine Infusion in Pre-eclamptic Patients
The purpose of this study is to investigate the effects of dexmedetomidine infusion on the stress response to intubation, postoperative analgesia, and renal functions (urinary output [UOP], creatinine and glomerular filtration…
- Trial name
- NCT03391609
- Testing
- Dexmedetomidine infusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Severe
Low-Sodium Diet for Postpartum Blood Pressure Control
The goal of this randomized controlled trial is to learn if a low-sodium diet improves postpartum blood pressure control in adults who were diagnosed with a late-onset hypertensive disorder of pregnancy.
- Conditions
- Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Severe, Pre-Eclampsia; Mild, Postpartum
- Trial name
- NCT07752056
- Testing
- Low Sodium Diet
- Volunteers
- 110 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Preeclampsia Mild to Moderate
The Effect of Awareness-Based Stress Reduction Training on Preeclampsia and Anxiety
Preeclampsia is a multisystem disease that occurs during pregnancy and carries risks into the postpartum period. This condition, which threatens maternal and fetal health, requires close monitoring and good care.
- Trial name
- NCT06841367
- Testing
- Mindfulness-based stress reduction training
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy; Pre-eclampsia, Mild
Role of Placental Growth Factor (PlGF) in the Management of Non-Severe Preeclampsia
Preeclampsia is an important disease that develops during pregnancy and it is one of the main contributors to maternal and fetal complications. The only known definitive treatment is delivery.
- Trial name
- MAP (NCT02373839)
- Testing
- Measurement of PlGF
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fetal Medicine Research Center, Spain
Coagulation Defect; Bleeding
Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia
Maternal hypotension is the most frequent complication of a spinal Anesthesia. The prevention of spinal hypotension appears more likely to decrease the frequency and severity of associated adverse maternal symptoms than the…
- Trial name
- NCT02622126
- Testing
- hydroxyethyl starch (6% 130/0.4), Hyperbaric bupivacaine, Morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Mild Pre-eclampsia, Severe Preeclampsia
İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
The purpose of this study, to investigate whether severity of preeclampsia is associated with altered levels of heavy metals (Cd, Hg, arsenic and Pb) in maternal blood, fetal blood, and maternal hair.
- Trial name
- NCT01906567
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Mild Pre-eclampsia, Severe Pre-eclampsia
Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach
Acid/base imbalances are not well understood in pre-eclamptics, and better tools are needed to allow a thorough and meaningful evaluation.
- Trial name
- NCT02164370
- Where
- 2 sites in United States, South Africa
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington