Clinical trials: Preanesthetic Medication
Anesthesia Recovery Period, Pain, Postoperative
Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the post-anesthesia care unit in patients…
- Trial name
- NCT00681174
- Testing
- Morphine, oxycodone, Paravertebral block
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Parma
Perioperative Anxiety, Preanesthetic Medication
Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety
The first goal of this study is to compare the efficacy and safety between anxiolysis by multimedia-distraction with an IPAD versus anxiolysis by premedication with midazolam prior to the induction.
- Conditions
- Perioperative Anxiety, Preanesthetic Medication, Inhalation Anesthesia, Ambulatory Surgery
- Trial name
- NCT04273035
- Testing
- Midazolam oral solution, IPAD
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Anesthesia
The Comparison of Different Administration Routes of Pediatric Premedication
The study purpose is to compare the effect of different Administration Routes of Pediatric Premedication (including oral administration, intramuscular injection, rectal perfusion, intranasal).
- Trial name
- NCT02313337
- Testing
- Oral administration, Intramuscular injection, Rectal perfusion
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dexmedetomidine, Sedation
Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings
The goal of this clinical trial is to assess the viability of dexmedetomidine hydrochloride nasal spray under minimal or no supervision and to further investigate novel clinical applications for this medication.
- Conditions
- Dexmedetomidine, Sedation, Safety, Preanesthetic Medication
- Trial name
- NCT07298525
- Testing
- Dexmedetomidine hydrochloride nasal spray
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Laryngoscopy, Preanesthetic Medication
Intramuscular Dexmedetomidine as Premedication
Many studies have been conducted for the feasibility of using dexmedetomidine as premedication. However, bradycardia and hypotension frequently occurred following the premedication with dexmedetomidine, either via intramuscular…
- Trial name
- NCT01937611
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangzhou First People's Hospital
Preanesthetic Medication
Impact of Preoperative Midazolam on Outcome of Elderly Patients
We aim to assess, if placebo compared to preoperative administration of midazolam in elderly patients is equal in regard to the global postoperative patient satisfaction
- Trial name
- I-PROMOTE (NCT03052660)
- Testing
- Midazolam
- Where
- 9 sites in Germany
- Volunteers
- 782 people
- Sponsor
- RWTH Aachen University
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis, Knee
Perineural Steroids for Peripheral Nerve Blocks
This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.
- Trial name
- NCT02462148
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Breast Neoplasms, Surgery Scheduled
Proof of Concept of the Aiinane Preoperative Risk Assessment Tool.
BACKGROUND: Each year, over 13,000 patients in Catalonia and more than 4 million worldwide experience last-minute surgery cancellations (LMC) due to preoperative inefficiencies.
- Conditions
- Breast Neoplasms, Surgery Scheduled, Surgery Related Complications Rate, Preanesthetic Medication
- Trial name
- aiinane-24-1 (NCT07021235)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Ancor Serrano
Preanesthetic Medication, Copeptin
The Effect of Midazolam Premedication on Copeptine Concentration in Blood
The study aim is to assess whether premedication with midazolam prior to surgery affects copeptin concentration in blood.
- Trial name
- NCT03474939
- Testing
- Midazolam Oral Tablet
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Pain, Postoperative, Postoperative Nausea and Vomiting
Anesthetic Premedication With a Cannabis Extract (Cannapremed)
Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- Cannapremed (NCT02283281)
- Testing
- Tetrahydrocannabinol, Dummy oromucosal
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Preanesthetic Medication
The Use of ADV6209 for Premedication in Pediatric Anesthesia
To evaluate the effect of ADV6209, a new oral Midazolam formulation, on preoperative anxiety and sedation levels in paediatric anaesthesia Primary Objective: Sedation score (mYPAS) 30 min after administration of the premedication…
- Trial name
- NCT03931057
- Testing
- ADV6209 (=gamma-cyclodextrin-Midazolam), Midazolam
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Medical University of Vienna
Surgical Procedures, Telemedicine
The Risk of Surgical Cancellation in Adult Patients Assessed by Telephone Versus In-person for Scheduled Non-cardiac Elective Surgery.
Telemedicine has been regulated in Colombia since 2006, with applications in anesthesia being explored since 2004 to improve accessibility and reduce costs.
- Conditions
- Surgical Procedures, Telemedicine, Preanesthetic Medication, Preoperative Care
- Trial name
- NCT06693869
- Where
- Colombia
- Volunteers
- 1,176 people
- Sponsor
- Universidad de Antioquia
Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress
Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology
This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted…
- Conditions
- Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress, Anesthesia, Vomiting
- Trial name
- NCT03681574
- Testing
- GABA 15mg/kg Group, GABA 30mg/kg Group
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Hospital Infantil Albert Sabin