Clinical trials: Pre-frail Elderly
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Arthritis, Cancer
MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.
Sufficient muscle strength helps to get out of a chair and can prevent falls. Up to 30% of older adults experience age-related loss of muscle strength, which can lead to frailty and health instability.
- Conditions
- Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease
- Trial name
- NCT04663685
- Testing
- Exercise program, Nutrition education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Pre-Frail Older Adults
Pharyngeal Exercise (Plus Protein)
The swallowing muscles are prone to decreased strength and function as part of the natural aging process which can lead to difficulty swallowing, malnutrition, and frailty.
- Trial name
- PE(PP) (NCT05963113)
- Testing
- Pharyngeal Swallowing Exercises, Protein Supplementation, MRI
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pre-frail Elderly, Frail Elderly
Dose Finding Study in Physically Frail Elderly to Measure 25(OH) Vitamin D Levels After Supplementation With Hy.D Calcifediol 25 SD/S and Vitamin D3
The purpose of this study is to assess the dose of Hy.D Calcifediol 25 SD/S (a metabolite of vitamin D3) which will achieve the range of mean serum 25(OH)D between 75-100nmol/L in physically frail elderly people after 24 weeks of…
- Trial name
- D-DOSE (NCT01868945)
- Testing
- 5 µg/day Hy.D Calcifediol, 10 µg/day Hy.D Calcifediol, 15 µg/day Hy.D Calcifediol
- Where
- Netherlands
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Pre-frail Senior Adults
What Are the Effects of a Bilateral Hip Exoskeleton During Daily Use by 65+ Adults?
Despite the huge popularity exoskeletons have gained in the past years and the benefits that they have shown to provide to users, there are still many aspects of wearing an exoskeleton that have yet to be determined.
- Trial name
- NCT06041100
- Testing
- Exoskeleton
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Fragility
Motorized Platform and Autonomy Among the Frail and Pre-frail Older Adult (PLATAUTONOMIE)
Highly diversified programs of physical activity in older people have shown their effectiveness in terms of improving functional capacities. Only one of these programs, to date, has used a motorized platform.
- Trial name
- NCT02850731
- Testing
- plate-forme Hu360®
- Sponsor
- University Hospital, Toulouse
Frail Elderly Syndrome
Effectiveness of a Socio-Community Health Intervention on Pre-Frailty in Older Adults
The objective of this study is: To evaluate the effectiveness of a health intervention with a socio-community approach on frailty in older adults with pre-frailty.
- Trial name
- NCT06663150
- Testing
- health intervention with a socio-community approach
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Keralty SAS. Colombia
Frail Elderly w/ Multimorbidity & Functional Limitations
The PAtient-Centred Team - Effectiveness and Cost-effectiveness Study
There is an urgent need to develop new care models for patients with long-term and complex needs. Our goal is services that are seamless, pro-active and person-oriented.
- Trial name
- PACT (NCT02541474)
- Testing
- Integrated care
- Where
- Norway
- Volunteers
- 1,200 people
- Sponsor
- University Hospital of North Norway
Frailty
Blood Flow Restriction on Functional Mobility in Pre-frail Older Adults
This study investigates the effect of blood flow restriction with resistance exercise on functional mobility in pre-frail older adults.
- Trial name
- NCT05209685
- Testing
- Resistance exercise on the lower extremities, Resistance exercise on the lower extremities with blood flow restriction
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- National Cheng Kung University
Health Services for the Aged, Geriatrics
Educational Guidelines Aimed at Pre-frail Elderly: Intervention Proposal
INTRODUCTION: aging is the natural process of deterioration of the reserves of biological systems, human beings are inherent to this process.
- Trial name
- NCT04997746
- Testing
- Multiprofessional educational interventions, Measurement of anthropometric measurements
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leonardo Paroche de Matos
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Protein Metabolism
Anabolic Response to Beef vs Plant Protein in (Pre)Frail Older Adults Using a Novel Stable Isotope Pulse Method
Frailty is a common clinical syndrome in older adults that increases the risk for poor health outcomes including falls, disability, hospitalization, and mortality.
- Trial name
- NCT07254403
- Testing
- Beef, Tofu
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Frail Elderly
Resistance Training to Optimize Health in Pre-frail Older Adults
Exercise programs, particularly resistance training programs using weights or resistance bands, can help improve or maintain mobility and function in older adults, preserve independent living, and improve quality of life.
- Trial name
- NCT02593084
- Testing
- Higher Intensity Resistance Training, Lower Intensity Resistance Training
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- McMaster University
Frail Elderly Syndrome, Frailty
Seated Physical Activity in Ageing
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- SPAA (NCT03141866)
- Testing
- Exercise Intervention 1: Move It Or Lose It (MIOLI), Exercise Intervention 2: Machine-based resistance training intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Colon Cancer, Fragility
Prehabilitation in Frail Colon Cancer
Objectives To investigate the impact of tele-supervised prehabilitation on functional capacity in frail colon cancer patients undergoing colorectal resection and to evaluate the effects of prehabilitation on muscle strength and…
- Trial name
- NCT03097224
- Testing
- Prehabilitation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Fatigue
Evaluation and Training of Muscle Fitness in Pre-frail Individuals
Muscle strength and endurance are important indexes of fitness. The muscle strength is the most important single predict factor of functional ability in aged frail individuals.
- Trial name
- NCT02122653
- Testing
- Weight training, Electronic muscle stimulator
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pre-frail Elderly
The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial
The primary objective is to determine the effect of SOD enzyme on frailty and health related quality of life among Indonesian pre-frail elderly.
- Trial name
- NCT02753582
- Testing
- SOD+Gliadin Capsule
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Frail Elderly
Effects of Remote Exercise on Physical Function in Pre-Frail Older Adults
This study aims to compare the effects of remote versus in-person exercise interventions on physical function, balance, gait stability, and fall efficacy in pre-frail older adults aged 65 years and above.
- Trial name
- NCT06672640
- Testing
- Remote Exercise Program, In-Person Exercise Program, Physical Activity Education
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kyungdong University
Cancer, Frailty
Qigong for Pre-frail and Frail Older Cancer Survivors
To-date, there is no evidence on qigong's effects for improving well-being of pre-frail and frail older cancer survivors. Our aim is to conduct a pilot study for testing out the feasibility and acceptability of a qigong…
- Trial name
- NCT04694066
- Testing
- Qigong, Light flexibility exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 28 people
- Sponsor
- The University of Hong Kong