Clinical trials: Postprandial Metabolism
Postprandial Hyperglycemia
The Acute Effect of Moderate Intensity Stair-Climbing on Postprandial Blood Glucose
This study aims to investigate the effect of moderate intensity stair-climbing bouts of various durations on postprandial blood glucose.
- Trial name
- NCT03400774
- Testing
- Stair-climbing
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Pre-Diabetes
BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes
This is a single-centre, 16-week, randomized, double-blind, placebo-controlled, 3-treatment arm pilot study to evaluate the efficacy and safety of BTI320 in the treatment of high risk subjects with pre-diabetes.
- Trial name
- NCT02358668
- Testing
- BTI320
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Nutritional and Metabolic Disease, Overweight
The Acute and Chronic Effects of Fruit Polyphenols on Chronic Disease (PPF)
1. The primary objective is to determine the effect of fruit polyphenols on postprandial lipoprotein triglyceride metabolism after consumption a standard high carbohydrate/fat breakfast meal with a beverage rich in fruit-derived…
- Trial name
- NCT01729949
- Testing
- Active Treatment Beverage
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Protein Metabolism
Effects of Protein Type and Mineral Form on Amino Acid Availability
To compare postprandial plasma amino acid availability, expressed as incremental area under the curve (iAUC), over a 6 hour period following ingestion of 25 g of different protein isolates in healthy, young adults.
- Trial name
- ProMin (NCT07677098)
- Testing
- Protein beverage
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Subjects
Glucose-dependent Insulinotropic Polypeptide (GIP) and Lipid Metabolism
The aim of this proposal is to examine whether endogenous GIP and exogenous GIP alone and in combination with insulin affect gastric emptying (GE), appetite, energy intake, energy expenditure (EE) and plasma levels of…
- Trial name
- NCT00999271
- Testing
- Incretin hormone - Glucose-dependent insulinotropic polypeptide (GIP)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Metabolic Health, Gut Hormones
Breaking Sitting and Metabolic Health in Sedentary Lean Adults
The purpose of this project is to investigate the effects of breaking up prolonged sitting on postprandial metabolic responses, gut hormones secretion and energy balance in sedentary lean adults.
- Conditions
- Metabolic Health, Gut Hormones, Energy Balance
- Trial name
- NCT05306613
- Testing
- Prolonged sitting, Breaking sitting
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Diabetes Mellitus
A Randomized Control Trial Comparing Linjeta Versus Humalog in Pumps: Effect on Postprandial Blood Sugars.
The purpose of this study is to determine if the use of Linjeta(tm) insulin when compared to Humalog will result in significantly lower episodes of hyperglycemia and hypoglycemia after a breakfast meal.
- Trial name
- NCT01067118
- Testing
- LINjeta U-100 Insulin, Humalog U-100
- Where
- 2 sites in United States
- Sponsor
- Stanford University
Type 2 Diabetes
Breakfast on Postprandial Hyperglycemia
Reduction of postprandial hyperglycemia (PPHG) is a major target in the treatment of type 2 diabetes (T2D). Skipping breakfast has been consistently associated with higher HbA1c and overall PPHG in subjects with type 2 diabetes…
- Trial name
- B-PPHG (NCT02411682)
- Testing
- Breakfast eating (YesB), Breakfast skipping (NoB)
- Volunteers
- 28 people
- Sponsor
- Hospital de Clinicas Caracas
Hyperglycemia, Postprandial
Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects
This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.
- Trial name
- NCT04914416
- Testing
- Verum T1, Verum T2, Verum T3
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fytexia
Obesity, Diabetes Mellitus, Type 2
Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid
Overweight and obesity are rising in prevalence and becoming a growing threat to public health. Obesity is associated with an increased all-cause mortality, impaired quality of life, and numerous of disorders.
- Trial name
- NCT06115304
- Testing
- Large liquid meal, spinal catheter and venous line
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mikkel Bring Christensen
Cardiovascular Risk Factor, Lipemia
Effect of Galactose Ingestion on Postprandial Lipemia
This study aims to assess the postprandial triglyceride response to the ingestion of a high-fat meal with co-ingestion of either galactose, or glucose.
- Trial name
- NCT03439878
- Testing
- Galactose, Glucose
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bath
Pregnancy
The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy
This study plans to learn more about how triglyceride levels in pregnancy affect newborn fat mass. Obesity in pregnancy, in the absence of gestational diabetes, is now the most common cause of large-for-gestational-age infants…
- Trial name
- NCT04394806
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hyperlipidemia
Effect of Different Types of Carbohydrates Consumed After Exercise on Blood Fat Levels
The increase in fat (i.e. triglyceride) in the blood after a meal is a well-established risk factor for heart disease (Nordestgaard et al. 2007).
- Trial name
- NCT02012855
- Testing
- Exercise, Diet (meal type)
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Type 2 Diabetes Mellitus, Postprandial Hyperglycemia
Effects of Insulin Treatment on Postprandial Platelet Activation in Patients With Non-insulin-dependent Diabetes Mellitus (NIDDM)
The postprandial phase in diabetic patients is characterized by a rapid increase in blood glucose levels, increase in platelet aggregation, LDL oxidation and over production of thrombin.
- Trial name
- NCT00771693
- Testing
- Insulin aspart (Novorapid®)
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Abdominal Obesity, Postprandial Lipemia
Alternating Energy Intake and Blood Fat Content After a Meal
Increasing evidence suggests that meal timing affects metabolic health. For example, intermittent fasting (IF) may have positive effects on plasma glucose and lipid levels, insulin sensitivity, and blood pressure.
- Conditions
- Abdominal Obesity, Postprandial Lipemia, Lipid Metabolism, Glucose Metabolism
- Trial name
- NCT04894526
- Testing
- Alternating Energy Intake, Regular Energy Intake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus
The Effect of Exenatide Compared to Lantus Insulin on Vascular Function in Type 2 Diabetes
The main goals of the study are to evaluate the effect of Exenatide on endothelial-dependent vasodilation, as measured by flow mediated dilation (FMD), to evaluate the effect on endothelial-independent vasodilation, as measured…
- Trial name
- NCT00353834
- Testing
- Exenatide, Glargine Insulin
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Joslin Diabetes Center
Prediabetes, Hyperglycemia
Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Sweetch is a personalized mobile-health platform coaching system (mobile phone app) designed to promote adherence to physical activity guidelines for people with prediabetes.
- Conditions
- Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance
- Trial name
- NCT03315663
- Testing
- Sweetch App & DBWS, Sweetch App Alone
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2, Hydroxymethylglutaryl-CoA Reductase Inhibitors
The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion
The primary objective of the present study is to evaluate the effect of HMG-CoA reductase inhibition during 14 days on the postprandial plasma GLP-1 response in healthy individuals.
- Trial name
- NCT03018444
- Testing
- Atorvastatin
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Type 2 Diabetes
High-amylose Barley (HIAMBA) in the Regulation and Prevention of Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of naturally produced high-amylose barley (Lean-baking barley®) on the postprandial glucose-metabolism in subjects…
- Trial name
- NCT04702672
- Testing
- 100% wheat (control), 100% Lean-baking barley®, 100% regular barley
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Physical Therapy
Reflexo Therapy for Gestational Diabetes Mellitus
The purpose of this study will be to detect the effects of Reflexo therapy of sole on GDM.
- Trial name
- NCT06976164
- Testing
- The standard antenatal care., Foot reflexology.
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University