Clinical trials: Postprandial Distress Syndrome
Functional Dyspepsia, Epigastric Pain Syndrome
Lansoprazole Versus Mosapride for Functional Dyspepsia
Functional dyspepsia is a common symptom complex with significant impact on quality of life. There is no standard treatment for functional dyspepsia but therapeutic efficacy of proton pump inhibitor (PPI) and prokinetic agent…
- Conditions
- Functional Dyspepsia, Epigastric Pain Syndrome, Post Prandial Distress Syndrome
- Trial name
- NCT00663897
- Testing
- lansoprazole, mosapride
- Where
- Taiwan
- Volunteers
- 329 people
- Sponsor
- Lotung Poh-Ai Hospital
Functional Dyspepsia, Postprandial Distress Syndrome
Acupuncture for Patients With Function Dyspepsia
Hypothesis: Acupuncture is efficacious and safe for patients with functional dyspepsia Design: A single blind randomized controlled trial 200 participants will be included Two arms: acupuncture and sham acupuncture group
- Trial name
- NCT01671670
- Testing
- acupuncture
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Functional Dyspepsia
Functional Dyspepsia: Validation of the Leuven Postprandial Distress Scale (LPDS) in a Placebo-controlled Trial
No instrument is available for the assessment of the symptoms in patients suffering from functional dyspepsia - postprandial distress syndrome patients - PDS. Indeed PDS is an unmet clinical need in drug development.
- Trial name
- NCT04464369
- Testing
- itopride
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postprandial Distress Syndrome
Traditional Chinese Medicine Xiang-sha-liu-jun Granules in Patients With Postprandial Distress Syndrome(PDS)
Functional dyspepsia (FD), which is one of the most common gastrointestinal disorders with high disease burden. Postprandial distress syndrome (PDS) is a common subtype of FD.
- Trial name
- NCT02762136
- Testing
- Xiang-sha-liu-jun granules
- Where
- 2 sites in China
- Volunteers
- 216 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Postprandial Distress Syndrome, Functional Dyspepsia
Postprandial Distress Itopride Cohort Trial
Functional Dyspepsia (FD) is a common gastrointestinal disorder affecting about 7.2% of the population, characterized by gastroduodenal symptoms without an identifiable organic cause.
- Conditions
- Postprandial Distress Syndrome, Functional Dyspepsia, Epigastric Pain Syndrome
- Trial name
- PASSPORT (NCT07165301)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia, FODMAP Diet
The Effect of a Low FODMAP Diet in Functional Dyspepsia Patients With Meal Related Symptoms
In this study, the investigators will evaluate the FODMAP diet as an alternative treatment for functional dyspepsia and explore its effect on different aspects of the pathophysiology of FD.
- Trial name
- FFD (NCT06388330)
- Testing
- low FODMAP diet
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia, Epigastric Pain Syndrome
Comparative Study of Epigastric Pain Syndrome and Postprandial Distress Syndrome
The purpose of this study is to compare postprandial distress syndrome and epigastric pain syndrome in demographics psychological features, infection of Helicobacter pylori, gastric emptying and therapeutic response to…
- Conditions
- Functional Dyspepsia, Epigastric Pain Syndrome, Post Prandial Distress Syndrome
- Trial name
- NCT00673972
- Testing
- gastric scintigraphy
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Functional Dyspepsia
DLBS2411 Treatment For Functional Dyspepsia
This is a 2-arm, prospective, double-blind, randomized and placebo-controlled study using DLBS2411 at a dose of 250 mg twice daily (before morning and evening meals), for a 4-week course of therapy, for the treatment of patients…
- Trial name
- NCT05248802
- Testing
- DLBS2411
- Where
- 8 sites in Indonesia
- Volunteers
- 106 people
- Sponsor
- Dexa Medica Group
Dyspepsia and Other Specified Disorders of Function of Stomach, Postprandial Distress Syndrome
Primary Care dySpEpsia rikkuNshiTo
Dyspepsia refers to chronic or recurrent upper gastrointestinal (GI) symptoms originating from the gastroduodenal region with a significant impact on patients' lives.
- Trial name
- PRESENT (NCT06482671)
- Testing
- Rikkunshi-to
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functioanl Dyspepsia, Post Prandial Distress Syndrome
Comparing Acotiamide and Itopride for the Management of Indigestion
This study is a randomized, double-blinded trial that will compare the effectiveness of two medications, acotiamide and itopride, in treating Functional Dyspepsia.
- Trial name
- NCT07449689
- Testing
- Acotiamide, itopride
- Volunteers
- 368 people
- Sponsor
- Aga Khan University
Functional Dyspepsia, Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth: A Prospective Registry
The purpose of this study is to investigate the prevalence of small intestinal bacterial overgrowth (SIBO) in patients who will be undergoing an enteroscopy as an outpatient procedure with symptoms of functional dyspepsia.
- Trial name
- SIBO (NCT01822470)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Dyspepsia
Phase III, Long-term, Open-label Safety Study of Z-338
The primary objective of this study is to evaluate the long-term safety of 100 mg Z-338 TID in European subjects with FD.
- Trial name
- NCT01973790
- Testing
- Z-338
- Where
- 36 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 207 people
- Sponsor
- Zeria Pharmaceutical
Functional Dyspepsia, Epigastric Pain Syndrome
Cognitive Behavioral Therapy for Functional Dyspepsia (Epigastric Pain Syndrome and Postprandial Distress Syndrome Subtypes)
The goal of this clinical trial is to learn whether adding Cognitive Behavioral Therapy (CBT) to standard medical treatment can improve symptoms in adults with Functional Dyspepsia.
- Conditions
- Functional Dyspepsia, Epigastric Pain Syndrome, Postprandial Distress Syndrome
- Trial name
- FD-CBT (NCT07577089)
- Testing
- Optimized Standard Treatment (OPT), Cognitive Behavioral Therapy + Optimized Standard Treatment (CBT + OPT)
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Avoidant/Restrictive Food Intake Disorder, Dyspepsia
Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia
Randomized controlled trial of an exposure-based behavioral treatment (CBT) in adults with functional dyspepsia who meet criteria for avoidant/restrictive food intake disorder (ARFID) with weight loss.
- Conditions
- Avoidant/Restrictive Food Intake Disorder, Dyspepsia, Feeding and Eating Disorders, Cognitive Behavioral Therapy
- Trial name
- NCT05587127
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Functional Dyspepsia
Rifaximin for Functional Dyspepsia
Functional dyspepsia is a very common medical condition, which occurs in up to 30% of people in the community. However, results of current pharmacological treatment on functional dyspepsia are unsatisfactory.
- Trial name
- NCT01643083
- Testing
- Rifaximin
- Where
- China
- Volunteers
- 95 people
- Sponsor
- The University of Hong Kong
Functional Dyspepsia
Zhizhu Kuanzhong Capsule for Patients With Functional Dyspepsia-Postprandial Distress Syndrome
A 13 weeks randomized, double-blind and placebo parallel-controlled trial will be conducted to evaluate the clinical efficacy and safety of Zhizhu Kuanzhong Capsule in the treatment of functional dyspepsia-postprandial distress…
- Trial name
- ZZKZ-FD (NCT04380233)
- Testing
- Investigational drug for Functional Dyspepsia-Postprandial Distress Syndrome
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Baptist University
Functional Dyspepsia, Postprandial Fullness Syndrome
Functional Dyspepsia: Validation of a Questionnaire for Symptom Assessment in FD PDS Subgroup
Fuctional dyspepsia is defined as the presence of symptoms thought to originate from the gastroduodenum, in the absence of any structural or metabolic disease that is likely to explain these symptoms.
- Trial name
- NCT04647955
- Testing
- Itopride
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postprandial Distress Syndrome
Acotiamide vs Itopride in Postprandial Distress Syndrome
The goal of this study is to "To compare the efficacy and safety of Acotiamide versus Itopride in patient with post prandial distress syndrome type of functional dyspepsia"
- Trial name
- NCT07174297
- Testing
- Acotiamide
- Volunteers
- 152 people
- Sponsor
- Getz Pharma
Functional Dyspepsia
Budesonide as a Treatment for Functional Dyspepsia
This clinical study is being conducted to evaluate the investigational drug, Budesonide, for the treatment of functional dyspepsia.
- Trial name
- BuDy (NCT06841406)
- Testing
- budesonide, Mannitol
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Post Prandial Distress Syndrome
A Dose-Ranging Study of ATI 7505 in Patients With Postprandial Distress Syndrome
To assess the efficacy of 3 oral dosing regimens of ATI 7505 compared to placebo in patients with PDS by comparing at the end of Day 42 the percentage of patients in each treatment group who have had adequate relief of…
- Trial name
- NCT00630370
- Testing
- 20 mg ATI 7505, 40 mg ATI 7505, 80 mg ATI 7505
- Where
- 64 sites in United States, Canada and 1 more
- Volunteers
- 6 people
- Sponsor
- Procter and Gamble