Clinical trials: Postpartum Hypertension
Gestational Diabetes Mellitus, Preeclampsia
User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study
Refine content and delivery of the mHealth delivered lifestyle intervention program through iterative testing with small groups of users who provide feedback through on-line asynchronous focus groups.
- Conditions
- Gestational Diabetes Mellitus, Preeclampsia, Gestational Hypertension, Pre-term Delivery
- Trial name
- NCT02384226
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Gestational Hypertension, Hypertension in Pregnancy
A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)
This trial is a pilot-scale, single institution randomized, placebo-controlled trial to assess the feasibility, acceptability, and efficacy of administering dapagliflozin for cardiovascular risk reduction in the postpartum…
- Conditions
- Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia
- Trial name
- DAPA-HP (NCT06785116)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Hypertension in Pregnancy, Postpartum Preeclampsia
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water…
- Trial name
- ACE (NCT05049616)
- Testing
- ACE Inhibitors and Diuretics, NIFEdipine ER
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The University of Texas Health Science Center, Houston
Preeclampsia
Post-Pregnancy Cardio Trial
Preeclampsia is a systemic pregnancy disorder and is associated with an increased cardiovascular risk later in life. This study will characterize myocardial tissue in patients after preeclampsia compared to controls and…
- Trial name
- PPC1 (NCT03313063)
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Postpartum Hypertension (PPHT)
Swiss Postpartum Hypertension Cohort
This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal…
- Trial name
- NCT04690660
- Testing
- Data collection for parameters of organ damage (cardiac and renal blood markers), Data collection for blood pressure (BP), Home-based blood pressure management (substudy)
- Where
- Switzerland
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypertension in Pregnancy, Preeclampsia
Response to Anti-hypertensives in Pregnant and Postpartum Patients
In this study, the investigators will evaluate the blood pressure response to nifedipine and labetalol in pregnant and postpartum patients, who present with hypertensive disease in pregnancy with severe range blood pressure…
- Trial name
- NCT03506724
- Testing
- Nifedipine, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Complication, Maternal Hypertension
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.
- Conditions
- Postpartum Complication, Maternal Hypertension, High Blood Pressure
- Trial name
- SCARPH (NCT05551104)
- Testing
- Oral Nifedipine, Oral Labetalol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Loma Linda University
Preeclampsia
Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure
The postpartum period represents a stage of the pregnancy-puerperal still rarely addressed scientifically. There are no reports in the literature and concrete enough to elucidate important issues, especially in the field of…
- Trial name
- CLONCAP (NCT01761916)
- Testing
- CLONIDINE, CAPTOPRIL
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pre-Eclampsia
Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial
IMPROVE is a pilot RCT with a behavioral intervention component (CardioPrevent program). The primary objectives of this pilot study are to assess the feasibility of the implementation of a postpartum CVD prevention lifestyle…
- Trial name
- IMPROVE (NCT03302260)
- Testing
- CardioPrevent® Program
- Volunteers
- 84 people
- Sponsor
- University of Calgary
Gestational Hypertension, Preeclampsia (PE)
Postpartum CO Rehabilitation
Some women who develop high blood pressure during pregnancy, such as gestational hypertension or preeclampsia, may continue to have slightly or moderately high blood pressure after giving birth.
- Trial name
- NCT06920537
- Testing
- Postpartum Cardio-obstetric Rehabilitation Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Hypertension
Staying Healthy After Childbirth: My Hypertension Education and Reaching Target Program for Postpartum
A study of Staying Healthy After Childbirth (STAC) and My Hypertension Education And Reaching Target (MyHEART) for postpartum (p) patients to determine if health coaching can increase 12-month postpartum care attendance…
- Trial name
- STAC-MyHEARTp (NCT05685251)
- Testing
- Health Coaching, Home Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Wisconsin, Madison
Preeclampsia, Preeclampsia Severe
Preeclampsia Educational Program Study (PrEPS)
Preeclampsia complicates approximately 8% of all pregnancies. A critical factor of outpatient monitoring is patient education; specifically, education regarding nature of the disease, ongoing short- and long-term risks, and…
- Conditions
- Preeclampsia, Preeclampsia Severe, Preeclampsia Mild, Preeclampsia Postpartum
- Trial name
- PrEPS (NCT06373367)
- Testing
- Illustration based application, Text based application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- MemorialCare Health System
Pre-Eclampsia, Gestational Hypertension
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
- Conditions
- Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03298802
- Testing
- Hydrochlorothiazide 50mg Tablet
- Where
- 2 sites in United States
- Volunteers
- 453 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Postpartum Preeclampsia
Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension
Hypertensive disorders of pregnancy are important cause of severe morbidity, long-term disability and death among both mothers and their babies.
- Trial name
- NCT03449277
- Testing
- Oral Tablet
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Hossam Ahmed Abd Ellah
Hypertensive Disorder of Pregnancy
Remote Postpartum Intervention Targeting Movement Behaviors After Hypertensive Disorders of Pregnancy
The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of a postpartum physical activity intervention after a pregnancy complicated by a Hypertensive Disorder of Pregnancy.
- Trial name
- NCT06019715
- Testing
- Postpartum Remote Physical Activity Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jackie Dziewior
Hypertension
Prevention of Severe Postpartum Hypertension
The purpose of this study is to determine whether postpartum administration of furosemide to women with antepartum hypertensive disorders (gestational hypertension, preeclampsia) or elevated blood pressure in the first 24 hours…
- Trial name
- NCT02450773
- Testing
- Furosemide, Potassium chloride
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Hypertensive Disorder of Pregnancy
Intensive Postpartum Antihypertensive Treatment
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by…
- Trial name
- IPAT (NCT05687344)
- Testing
- Nifedipine ER
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Preeclampsia, Postpartum Period
The PreEclampsia Postpartum Prevention Trial
The goal of this clinical trial is to learn if a postpartum bundle intervention can improve cardiometabolic health and lifestyle-related factors in women who have had preeclampsia during their first pregnancy.
- Conditions
- Preeclampsia, Postpartum Period, Hypertension, Cardiovascular Diseases
- Trial name
- PEPP (NCT07199283)
- Testing
- Bundle Intervention
- Where
- 2 sites in Sweden
- Volunteers
- 356 people
- Sponsor
- Karolinska Institutet
Hypertension in Pregnancy, Preeclampsia Severe
Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period
This study evaluates whether nifedipine or enalapril is better at decreasing the amount of medical resources used in the postpartum period by women who have high blood pressure in pregnancy and the postpartum period.
- Conditions
- Hypertension in Pregnancy, Preeclampsia Severe, Gestational Hypertension, Postpartum Preeclampsia
- Trial name
- NCT04236258
- Testing
- NIFEdipine ER, Enalapril
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital