Clinical trials: Postoperative Sleep Disturbance, active
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems.
- Trial name
- NCT07354542
- Testing
- Virtual Reality-Based Relaxation, Traditional Relaxation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Sleep Wake Disorders, Lung Neoplasms
Low-Frequency rTMS for Sleep After Thoracoscopic Lung Resection
This single-center randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) improves postoperative inpatient sleep in adults undergoing elective…
- Trial name
- TMS-SLEEP-VATS (NCT07796451)
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 220 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Patient Readmission
Predicting Hospital Readmission for Surgical Patients Using Deep Learning Models With Smart Watch and Smart Ring Sensors Data
Hospital readmissions are an important measure of healthcare quality and safety. These events create a substantial burden for patients, families, and health systems because they may increase costs, extend recovery time, and lead…
- Trial name
- NCT07349901
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Getúlio Vargas University Hospital
Dental, Dental Extraction
Insomnia and Post-Dental Surgery Pain: A Prospective Study
The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures.
- Conditions
- Dental, Dental Extraction, Insomnia
- Trial name
- INDOLC (NCT07712432)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteoarthritis, Knee, Osteoarthritis, Hip
Promoting Sleep to Alleviate Pain - Arthroplasty
PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Insomnia, Surgery
- Trial name
- PROSAP-A (NCT06145516)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Sleep education therapy (SET)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Delirium - Postoperative, Sleep Problems
Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery
This is a multicenter, randomized, controlled clinical trial aimed to determine whether preoperative sleep interventions could reduce the incidence of adverse outcomes, such as postoperative delirium, in sleep-disordered…
- Conditions
- Delirium - Postoperative, Sleep Problems, Congenital Heart Disease (CHD)
- Trial name
- NCT06879431
- Testing
- cognitive-behavioral intervention
- Where
- China
- Volunteers
- 544 people
- Sponsor
- Yan Fuxia
Postoperative Sleep Disturbance, Thoracoscopic Surgery
Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is the mainstream minimally invasive procedure in thoracic surgery; However, the high-stress state during the perioperative period and severe postoperative pain often lead to…
- Trial name
- NCT07811401
- Testing
- Lemborexant 5 mg
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Adults, Major Noncardiac Surgery
Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery
Sleep disturbances are common early after major surgery, and are associated with delayed recovery. A previous study showed that dexmedetomidine-esketamine combination as a supplement to patient-controlled intravenous analgesia…
- Conditions
- Adults, Major Noncardiac Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT06859892
- Testing
- Dexmedetomidine-esketamine combination
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, Vascular Aneurysm
OSA as a Remote Ischemic Preconditioning in Vascular Surgery
Ischemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure.
- Conditions
- Obstructive Sleep Apnea, Vascular Aneurysm, Ischemia Reperfusion Injury
- Trial name
- NCT04630535
- Testing
- aorto-bifemoral bypass surgery
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone
The aim of this study is to explore the relationship between preoperative sleep disorders, melanin-concentrating hormone (MCH), and delayed neurocognitive recovery early after surgery in older adult patients undergoing spinal…
- Trial name
- NCT07392840
- Volunteers
- 50 people
- Sponsor
- Minia University
Postoperative Sleep Quality, Postoperative Behaviour
Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION)
Nausea and vomiting are common complications after anaesthesia, and anaesthetists routinely give medications to prevent them. Dexamethasone and ondansetron are the two most commonly used agents and have a long safety record.
- Conditions
- Postoperative Sleep Quality, Postoperative Behaviour, Postoperative Recovery in Children, Postoperative Nausea and Vomiting (PONV)
- Trial name
- SCORPION (NCT07777276)
- Testing
- Dexamethasone (IV), Ondansetron iv
- Where
- 3 sites in Australia, Brazil
- Volunteers
- 500 people
- Sponsor
- Telethon Kids Institute
Obstructive Sleep Apnea, Postoperative Analgesia
Oliceridine Versus Sufentanil Analgesia for Postoperative Patients With Obstructive Sleep Apnea
Opioids are frequently used for postoperative analgesia but may induce side effects. Opioid-induced respiratory depression is the most dangerous side effect of opioids.
- Conditions
- Obstructive Sleep Apnea, Postoperative Analgesia, Oliceridine, Sufentanil
- Trial name
- OSA (NCT07753785)
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 851 people
- Sponsor
- Peking University First Hospital
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Postoperative Sleep Disturbance
Transcutaneous Electrical Acupoint Stimulation for Perioperative Sleep Disturbances in Cancer Patients
Postoperative sleep disturbance (POSD) is highly prevalent among cancer patients after tumor resection, affecting 43%-80% of perioperative individuals.
- Trial name
- NCT07654075
- Testing
- transcutaneous electrical acupoint stimulation,TEAS
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Second Hospital of Shanxi Medical University
Pain, Postoperative, Sleep
Effect of Foot Bath on Pain, Sleep, and Comfort Levels After Abdominal Surgery
The aim of this study was to investigate the effects of foot bath application on pain level, comfort and sleep quality in the postoperative period. H1: Foot baths have a postoperative pain-reducing effect.
- Trial name
- NCT07366567
- Testing
- Foot bath device
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Trakya University
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health