Clinical trials: Postoperative Mortality
Postoperative Mortality, Anesthesia
The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China
At present, the elderly population in China has reached 241 million, and there are more than 20 million elderly surgical patients every year, accounting for about 25% of the surgical population.
- Conditions
- Postoperative Mortality, Anesthesia, Elderly Patients, Noncardiac Surgery
- Trial name
- NCT04389008
- Testing
- no interventions
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Chinese PLA General Hospital
Hematoma, Subdural, Chronic
Irrigation of Chronic Subdural Hematomas - is More Better?
There are numerous reported ways to treat chronic subdural hematomas (CSDH) and practice is still differing considerably between departments.
- Trial name
- NCT01930617
- Testing
- Burr hole surgery with various drainage techniques
- Where
- 3 sites in Norway, Sweden
- Volunteers
- 1,258 people
- Sponsor
- St. Olavs Hospital
Postoperative Complications, Other Complications of Other Bariatric Procedure
Edmonton Obesity Staging System: Post-operative Outcome and 30-day Mortality
The Edmonton Obesity Staging System (EOSS) is a more comprehensive measure of obesity-related diseases and predictor of mortality than BMI or waist circumference.
- Trial name
- NCT02607267
- Testing
- LSG and LRYGB
- Where
- Germany
- Volunteers
- 534 people
- Sponsor
- Sana Klinikum Offenbach
Myocardial Infarction (MI), Perioperative Myocardial Injury
High-Sensitivity Troponin T Kinetics and 30-Day Outcomes After Major Abdominal Surgery (TROP-MAS)
Major abdominal surgery (MAS) carries a high risk of 30-day mortality (>5%). Perioperative myocardial injury (PMI) and myocardial injury after noncardiac surgery (MINS) frequently develop asymptomatically due to surgical…
- Conditions
- Myocardial Infarction (MI), Perioperative Myocardial Injury, Sepsis, Digestive System Surgical Procedures
- Trial name
- TROP-MAS (NCT07850492)
- Testing
- High-sensitivity cardiac troponin T (hs-cTnT) surveillance
- Where
- Vietnam
- Volunteers
- 650 people
- Sponsor
- Bach Mai Hospital
Fracture, Infection
A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications
The overall goal of the project is to reduce the incidence of post hip fracture morbidity and mortality by conducting geriatric fellow periodic home visits.The assessment will be multidisciplinary and will include assessments of…
- Conditions
- Fracture, Infection, Depression, Gait Instability
- Trial name
- NCT02058329
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwell Health
Acute Renal Failure, SIRS
BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients
The purpose of this study is to find out whether acute renal failure is associated with BK virus reactivation in postoperative/posttraumatic critically ill patients with severe SIRS/sepsis and shock.
- Conditions
- Acute Renal Failure, SIRS, Sepsis, Critically Ill
- Trial name
- BICUK (NCT00736827)
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- University of Ulm
External Causes of Morbidity and Mortality
Post Operative Walking Enhancements for Recovery (POWER) Trial
This study is a non-blinded randomized controlled trial. Consenting participants will be randomized to routine post-operative ambulation vs.
- Trial name
- POWER (NCT01254851)
- Testing
- goal-augmented post-operative care
- Where
- 2 sites in United States
- Volunteers
- 146 people
- Sponsor
- Loyola University
Patients Undergoing Cardiac Surgery
The Relation Between Preoperative ScO2 and the Postoperative Course of Humoral Organ Dysfunction Markers.
Cerebral oxygen saturation (ScO2) is a measure of cerebral and systemic oxygen delivery to demand ratio. An observational trial in a heterogeneous cohort of 1078 patients patients revealed that a ScO2 below 50% absolute during…
- Trial name
- NCT01409941
- Volunteers
- 765 people
- Sponsor
- University of Luebeck
Surgery, Postoperative Complications
Colombian Surgical Outcomes Study - COLSOS
An observational, analytical, multicentre prospective cohort study will be conducted throughout Colombia. A sample size of 1353 patients is needed to achieve significance in our primary objective; however, convenience sampling is…
- Conditions
- Surgery, Postoperative Complications, Hospital Mortality
- Trial name
- COLSOS (NCT05147623)
- Testing
- Any surgery/procedure
- Where
- 2 sites in Colombia
- Volunteers
- 1,353 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Postoperative Complications, Patient Care Team
Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population
High risk surgical patients are subject to complications that impact rehabilitation time, overall mortality and costs. This project proposes the creation of a post-surgery care pathway called Extended Care in High-Risk Surgical…
- Trial name
- EXCARE (NCT04187664)
- Testing
- Postoperative Monitoring, High-sensitivity cardiac troponin testing
- Where
- Brazil
- Volunteers
- 1,720 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Perioperative Care
The Impact of Preoperative Statin Therapy and and Its Intensity on Postoperative and Mortality and Morbidity
Statins are among the most widely prescribed drugs worldwide, and their benefits in cardiovascular risk reduction are well established.
- Trial name
- STIMM (NCT07575737)
- Where
- 2 sites in Sweden
- Volunteers
- 70,000 people
- Sponsor
- Karolinska Institutet
Surgery, Death
Risk Calculators Validation for Elective Major General Surgery
Nowadays, over 300 million surgical operations take place every year worldwide, which increase at a rate of 33.6% comparing data from 2005 to 2013.
- Trial name
- RCVEMG (NCT04041076)
- Testing
- Major surgical operation
- Where
- Hong Kong
- Volunteers
- 5,000 people
- Sponsor
- Chinese University of Hong Kong
Emergency Laparotomy
Evaluation of Surgical Risk Prediction Tools.
Introduction: In modern surgery, the prediction of perioperative death gains significant importance due to the availability of treatment options, means of improving the surgical outcome and for proper patient information.
- Trial name
- NCT04615520
- Where
- Greece
- Volunteers
- 660 people
- Sponsor
- University Hospital of Crete
Heart Disease, Cardiovascular Disease
Best Bypass Surgery (BBS) Trial
There is evidence linking cardiopulmonary bypass to negative side effects when used for coronary artery bypass grafting. Coronary artery bypass grafting can be performed without the use of cardiopulmonary bypass.
- Trial name
- NCT00120991
- Testing
- Coronary artery bypass grafting
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery With Cardiopulmonary Bypass
Beta Blocker Use in Cardiac Surgery and Association With Postoperative Course
The objective of this study is to describe in a cohort of cardiac surgery patients the use of beta-blockers before surgery and their maintenance or withdraw according to international recommendations in order to compare patients…
- Trial name
- BLOCK (NCT04769752)
- Testing
- collection of the allocated treatment, collection of medical complications
- Where
- France
- Volunteers
- 1,789 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Surgery
Epidemiology of Perioperative Care in Sweden
The Epidemiology of Perioperative Care in Sweden (EPeCS) study is a registry-based, retrospective extensive analysis of the whole adult (≥18 years) surgical population in Sweden during six full years, 1 January 2015 - 31 December…
- Trial name
- EPeCS (NCT05560815)
- Testing
- Any surgical procedure
- Where
- Sweden
- Volunteers
- 1,500,000 people
- Sponsor
- Linkoeping University
Postoperative Morbidity, Postoperative Mortality
Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Conditions
- Postoperative Morbidity, Postoperative Mortality, Hemostasis Change
- Trial name
- HAEMO (NCT03420261)
- Testing
- 0.9% saline, HES 130/0.4
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Medical Device
Impact on the Time to Diagnosis of Serious Postoperative Complications by a Controlled Connected Medical Device
Post-operative mortality in case of scheduled surgery is 3% in France (Lancet 2013) mainly due to cardiovascular or respiratory complications, by decompensation of pre-existing pathologies.
- Trial name
- SMARTANGEL (NCT05380310)
- Testing
- Active "SMART ANGEL" solution, Inactive "SMART ANGEL" solution
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-Cardiac Arrest Syndrome
The Effect of IABP Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome
The prevalence of cardiac arrests is still high worldwide. Despite the return of spontaneous circulation (ROSC), mortality and morbidity in post cardiac arrest patients is reported high.
- Trial name
- NCT03638609
- Testing
- Intra Aortic Balloon Pump
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- Universitas Indonesia
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham