Clinical trials: Postoperative Mortality
Blood Pressure, Intraoperative Hypotension
Perioperative Personalized Blood Pressure Management: IMPROVE-multi
Rates of major complications and mortality in the first weeks after surgery remain very high: postoperative mortality is still around 2% in central Europe and the United States.
- Conditions
- Blood Pressure, Intraoperative Hypotension, Postoperative Complications, Surgery
- Trial name
- IMPROVE (NCT05416944)
- Testing
- Personalized blood pressure management
- Where
- Germany
- Volunteers
- 1,272 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anastomotic Leak
Risk Factors Associated With Anastomotic Leak and Perioperative Mortality in Elderly
This is a retrospective cohort study of all consecutive patients who underwent colon or rectal resection, between the years 2012-2017 at Rabin Medical Center, a tertiary referral center in Israel.
- Trial name
- NCT04518384
- Testing
- colon or rectum resection
- Where
- Israel
- Volunteers
- 536 people
- Sponsor
- Rabin Medical Center
Patients Who Underwent Surgery for Congenital Heart Disease
Influence of Tidal Volume During Mechanical Ventilation on Postoperative Clinical Outcome in Pediatric Patients Undergoing Congenital Heart Surgery
High tidal volume during mechanical ventilation has been reported to increase mortality in patients with acute lung injury or acute respiratory distress syndrome.
- Trial name
- NCT02081274
- Testing
- Surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Surgical Risk Assessment, Postoperative Mortality
Preoperative Cardiac Power Output and P-POSSUM Score
This study aims to investigate the relationship between preoperative Cardiac Power Output (CPO), which reflects the pumping capacity of the heart, and the P-POSSUM score, a widely used surgical risk assessment tool, in patients…
- Conditions
- Surgical Risk Assessment, Postoperative Mortality, Postoperative Morbidity
- Trial name
- NCT07454564
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Necmettin Erbakan University
Heart Failure, Diastolic Heart Failure
Heart Failure and Postoperative Outcome in Surgery - a National Registry Study
The study is an exploratory study that aims to explore the incidence of heart failure in a national surgical cohort, and to compare postoperative mortality and morbidity in patients with and without heart failure.
- Conditions
- Heart Failure, Diastolic Heart Failure, Systolic Heart Failure
- Trial name
- NCT07634822
- Where
- 2 sites in Sweden
- Volunteers
- 2,200,000 people
- Sponsor
- Umeå University
Abdominal Surgery, Postoperative Complications
P-POSSUM for Outcomes After Abdominal Surgery
Postoperative complications after abdominal surgery can lead to prolonged recovery, intensive care admission, and death. The P-POSSUM score is a commonly used surgical risk prediction tool, but its performance may vary between…
- Conditions
- Abdominal Surgery, Postoperative Complications, Surgical Risk Prediction, Postoperative Mortality
- Trial name
- PPOSSUM-ABD (NCT07667764)
- Where
- Vietnam
- Volunteers
- 3,000 people
- Sponsor
- Bach Mai Hospital
Unconscious State
The Effect of BIS Monitorization to Intraoperative Anesthetic Consumption During Coronary Artery Surgery
213 patients undergoing elective on-pump coronary artery bypass grafting (CABG) were enrolled into this prospective-clinical trial.After hundred and sixty three patients were excluded due to various reasons, 50 patients were…
- Trial name
- NCT02520947
- Testing
- BIS, Desflurane
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Fluid Balance, Input and Output
Fluid Balance and Clinical Outcomes
This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration).
- Conditions
- Fluid Balance, Input and Output, Inflammatory Mediators, Acute Kidney Injury
- Trial name
- NCT01168583
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Florida
Hip Fracture
Association Between HRV and Postoperative Mortality in Hip Fracture Patients
165 patients admitted to two hospitals were included and short-time HRV measurements were obtained. Mortality data were gathered from the Norwegian central address register.
- Trial name
- HRVHip (NCT03426501)
- Volunteers
- 165 people
- Sponsor
- Vestre Viken Hospital Trust
Orthopedic Procedures, Obesity
Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures
Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries.
- Trial name
- BMIORTHO (NCT04827888)
- Testing
- Orthopaedic surgery
- Where
- Lebanon
- Volunteers
- 76,189 people
- Sponsor
- American University of Beirut Medical Center
Postoperative Complications
Prospective Validation of ExCARE Model for 30-Day Postoperative Mortality
This prospective observational cohort study aims to validate the ExCARE risk model, derived from four preoperative variables (age, ASA-PS classification, procedure urgency, and surgical magnitude), for predicting in-hospital…
- Trial name
- ExCARE-HNSC (NCT07293377)
- Where
- Brazil
- Volunteers
- 3,000 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Gastric Cancer
Annual Hospital Volume and and Short-term Postoperative Outcomes After Gastric Cancer Resection
The effect of centralisation measures on the operative outcomes after gastric cancer resection in Switzerland has not been highlighted yet.
- Trial name
- NCT07072429
- Testing
- Gastric cancer resection
- Where
- Switzerland
- Volunteers
- 3,112 people
- Sponsor
- Cantonal Hospital of St. Gallen
Stomach Neoplasms
The Effect of Preoperative Inflammation-based Scores on Postoperative Morbidity and Mortality for Laparoscopic Gastrectomy
The purpose of this study is to explore the effect of preoperative inflammation-based scores on postoperative morbidity and mortality for laparoscopic gastrectomy.
- Trial name
- NCT02930291
- Where
- China
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Postpartum Hemorrhage
Oral Misoprostol Versus Intravenous Oxytocin in Preventing Blood Loss After Non-scheduled Cesarean Section
Postpartum hemorrhage (PPH) ranks among the leading causes of maternal morbidity and mortality, both in developed and developing countries.
- Trial name
- NCT00107874
- Testing
- misoprostol
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University Hospital, Basel, Switzerland
Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension
Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial
Pulmonary hypertension (PH) has three main types, pre-capillary PH, post-capillary PH, and combined pre-capillary and post-capillary PH, and it is based on mean pulmonary arterial pressure (PAP) > 20 mmHg measured with a right…
- Conditions
- Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension, Post Operative
- Trial name
- IPES (NCT06060366)
- Testing
- Pulmonary endarterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Gastric Cancer, Siewert Type III Adenocarcinoma of Esophagogastric Junction
Postoperative Morbidity and Mortality After Gastric Cancer Surgery
Gastric cancer is still one of the main health care issue and gastrectomy with lymph node dissection is the only chance to be cure.
- Conditions
- Gastric Cancer, Siewert Type III Adenocarcinoma of Esophagogastric Junction, Stomach Cancer
- Trial name
- GASTROSTAT (NCT06277908)
- Testing
- Elective Surgery for gastric cancer
- Where
- 9 sites in Russia
- Volunteers
- 700 people
- Sponsor
- P. Herzen Moscow Oncology Research Institute
Morbid Obesity
Sleeve Gastrectomy: Outcome, Morbidity and Mortality. A Multicentric Retrospective Trial
Laparoscopic sleeve gastrectomy (LSG) is currently the most frequent primary bariatric procedure performed worldwide. LSG is a safe and effective technique in terms of excess weight loss and it is, moreover, a powerful metabolic…
- Trial name
- PSICHE (NCT04643262)
- Testing
- Sleeve Gastrectomy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Post Hepatectomy Liver Failure
Early Postoperative Extracorporal Liver Support Therapy (ELS) as a Tool to Manage Post Hepatectomy Liver Failure (PLF)
Early postoperative extracorporal liver support therapy (ELS) as a tool to manage post hepatectomy liver failure (PLF). Post-operative liver failure (PLF) has been identified as a major risk factor leading to increased morbidity…
- Trial name
- NCT03011424
- Testing
- Extracorporeal liver support therapy (ELS)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska University Hospital
Gastric Cancer
Gastric Cancer Surgery in Elderly Patients
Gastric cancer is most frequent after the fifth decade of life. Surgical risk is higher in aged population because of general health condition may affect the postoperative result.
- Trial name
- GCSEP (NCT03777540)
- Testing
- Gastric resection
- Volunteers
- 236 people
- Sponsor
- University of Bologna