Clinical trials: Postoperative Hypoxemia, open to volunteers
Postoperative Hypoxemia, Position Differences
Effect of Postural Changes on Postoperative Hypoxemia
The goal of this clinical trial is to learn which positioning strategy works better to prevent postoperative hypoxemia in surgical patients: semirecumbent positioning or lateral positioning.
- Trial name
- NCT07161817
- Testing
- Lateral positioning, Semirecumbent positioning
- Volunteers
- 1,200 people
- Sponsor
- Yuhu Ma
Hypoxemia, Ventilator Lung
Driving Pressure-guided Lung Protective Ventilation
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving…
- Trial name
- DPV (NCT06361420)
- Testing
- Driving pressure-guided positive end expiratory pressure, Optimal oxygenation-guided positive end expiratory pressure, Ventilation strategy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Yong Lin, PhD
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Lung Diseases
Comparison of Two Strategies of One-lung Ventilation in Patients Undergoing Carcinological Lung Resection Surgery.
During thoracic surgery, one-lung ventilation (OLV) is associated with hypoxemia, lung injury, and perioperative respiratory complications.
- Trial name
- I-PEEP-THO (NCT05525312)
- Testing
- "Open-lung" protective ventilation strategy, "Standard" protective ventilation strategy
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Esophageal Carcinoma, Esophageal Adenocarcinoma
Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy
This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy.
- Conditions
- Esophageal Carcinoma, Esophageal Adenocarcinoma, Esophagectomy, PaO2
- Trial name
- NCT07309991
- Where
- 6 sites in China
- Volunteers
- 2,500 people
- Sponsor
- Sun Yat-sen University
Hypoxemia, Postoperative Complications
Heated Humidified Oxygen in PACU Patients
This study aims to determine whether heated and humidified oxygen therapy, compared with conventional room-temperature oxygen therapy, reduces the incidence of early hypoxemia in adult patients recovering from general anesthesia…
- Conditions
- Hypoxemia, Postoperative Complications, Anesthesia Recovery Period
- Trial name
- NCT07778420
- Testing
- Heated and Humidified Oxygen Therapy, Room-Temperature Oxygen Therapy
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Postoperative Hypoxemia
Preoperative ROX Index for Predicting Early Postoperative Hypoxemia in ENT Surgery
Early postoperative hypoxemia is a frequent complication after elective ear, nose, and throat (ENT) surgery and may adversely affect recovery in the post-anesthesia care unit (PACU).
- Trial name
- NCT07344103
- Testing
- rox ındex
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istinye University
Hypoxemia
Reminder-enhanced Incentive Spirometry Evaluation
The purpose of this study is to test whether automatic reminders with a light and a soft sound help patients improve deep breathing exercises after surgery.
- Trial name
- RISE (NCT07728214)
- Testing
- Alarms ON
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Perioperative Diaphragmatic Excursion
Diaphragmatic Excursion Changes and Postoperative Oxygenation After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy and the associated pneumoperitoneum can impair diaphragmatic mechanics and reduce postoperative oxygenation.
- Trial name
- NCT07332728
- Testing
- Standard perioperative care with observational diaphragm ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istinye University
Postoperative Complications, Respiratory Insufficiency
Optimal PEEP for Postoperative Oxygenation and Lung Aeration (ULTRASVENT-2)
The purpose of this multicenter, randomized controlled trial (ULTRASVENT-2) is to evaluate the effect of different positive end-expiratory pressure (PEEP) levels on postoperative oxygenation and lung aeration in adult patients…
- Conditions
- Postoperative Complications, Respiratory Insufficiency, Pulmonary Atelectasis, Positive-End Expiratory Pressure
- Trial name
- ULTRASVENT-2 (NCT07613177)
- Testing
- Intraoperative Positive End-Expiratory Pressure (PEEP) Regulation
- Where
- Russia
- Volunteers
- 360 people
- Sponsor
- Moscow Multidisciplinary Clinical Center "Kommunarka"
Postoperative Pulmonary Complications (PPCs), Hypoxemia
Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients…
- Trial name
- LUS-POSTOP (NCT07515001)
- Volunteers
- 97 people
- Sponsor
- Dicle University
Hypoxemia
Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative Hypoxemia
Hypoxemia is a common complication in the post-anesthesia care unit (PACU) and represents one of the most meaningful factors associated with poor patient prognosis. Obese patients have a relatively higher incidence of hypoxemia.
- Trial name
- NCT07827131
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Hypoxemia
Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia
Using prospective real-world data, this study aims to determine whether the lateral decubitus position reduces the incidence of post-procedure hypoxemia in patients undergoing painless gastroscopy/colonoscopy, thereby providing a…
- Trial name
- NCT07545642
- Testing
- Lateral decubitus position group (Group L), Supine position group (Group S)
- Where
- China
- Volunteers
- 960 people
- Sponsor
- General Hospital of Ningxia Medical University
Pulmonary Complications, Hypoxemia During Surgery
Association of Different Tidal Volumes and Postoperative Pulmonary Complications
The incidence of lung cancer in China is increasing year by year. Currently, the treatment primarily based on video-assisted thoracoscopic surgery (VATS) is still considered the optimal approach for early-stage non-small cell…
- Conditions
- Pulmonary Complications, Hypoxemia During Surgery, Thoracic Surgery, Video Assisted, One Lung Ventillation (OLV)
- Trial name
- NCT07372378
- Volunteers
- 650 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Postoperative Hypoxemia
Transoral Nasal Cannula Oxygen Therapy for Mouth-Breathing Patients in the Postanesthesia Care Unit
Postoperative hypoxemia is a common complication in the postanesthesia care unit (PACU). Patients who breathe through the mouth after tracheal extubation may receive limited benefit from standard nasal cannula oxygen therapy…
- Trial name
- NCT07841223
- Testing
- Transoral nasal cannula oxygen delivery
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypoventilation, Hypoxemia
Postoperative Respiratory and Activity Monitoring
This study plans to learn more about specific breathing and activity recommendations for patients after surgery. Participants will be monitored after abdominal surgery to identify what activities help them breathe better and…
- Conditions
- Hypoventilation, Hypoxemia, Postoperative Pulmonary Complications
- Trial name
- NCT06239831
- Testing
- ExSpiron and ActivPAL Monitors
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Postoperative Hypoxemia
Effect of Different Body Positions on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy
Through a multicenter, three-arm randomized controlled trial design, this study aimed to compare the effects of three positioning strategies-side-lying with elevated head position, supine with elevated head position, and standard…
- Trial name
- NCT07587970
- Testing
- lateral decubitus head-up position (LH group), supine head-up position (SH group), standard lateral decubitus position group (SL group)
- Where
- China
- Volunteers
- 1,617 people
- Sponsor
- General Hospital of Ningxia Medical University
Postoperative Hypoxemia
Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery
This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂/FiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients…
- Trial name
- NCT07401589
- Testing
- Standard of Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University