Clinical trials: Postoperative Hypoparathyroidism
Postoperative Hypoparathyroidism
Treatment of Postoperative Hypoparathyroidism Using Cultured Allogenic Parathyroid Cells
The idea of the project is to develop a method of treatment of postoperative hypoparathyroidism using cultured allogenic parathyroid cells.
- Trial name
- NCT05186883
- Testing
- Allogenic parathyroid cells, Standard treatment according to the Clinical protocols
- Volunteers
- 20 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Thyroid Neoplasms, Thyroid Diseases
Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy
This study will see if the use of near infrared autofluorescence (NIRAF) detection with a 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during total thyroidectomy (TTx) is better than surgeon's detection…
- Conditions
- Thyroid Neoplasms, Thyroid Diseases, Hypoparathyroidism, Endocrine System Diseases
- Trial name
- NCT05022667
- Testing
- PTeye
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Michigan
Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism
PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"
This study aims to investigate whether an earlier measurement of parathyroid hormone can reduce the number of patients who develop symptomatic hypoparathyroidism.
- Conditions
- Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism, Hypoparathyroidism Post-surgical
- Trial name
- PRESSPAR (NCT07491601)
- Testing
- Active vitamin D, Calcium
- Where
- Germany
- Volunteers
- 336 people
- Sponsor
- Nicolas Schlegel
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Secondary Hyperparathyroidism, Chronic Kidney Disease-Mineral and Bone Disorder
Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa).
This is a pilot randomized controlled trial aimed to evaluate the effect of teriparatide on the clinical course of hypocalcemia after parathyroidectomy for secondary hyperparathyroidism in dialysis-dependent patients.
- Conditions
- Secondary Hyperparathyroidism, Chronic Kidney Disease-Mineral and Bone Disorder, Dialysis, Hypocalcemia
- Trial name
- TeriCa (NCT04750460)
- Testing
- Teriparatide
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Saint Petersburg State University, Russia
Hypoparathyroidism Postprocedural
Study on the Effects of Hypoparathyroidism on Post-thyroidectomy Health-related Quality of Life (QoL-hPTP)
Our study will evaluate the health related quality of life (HRQoL) after a thyroidectomy and the relevance of postoperative hypoparathyroidism.
- Trial name
- QoL-hPTP (NCT04604808)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Hypoparathyroidism
Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
- Trial name
- NCT04372225
- Testing
- analysis of hypocalcemia
- Where
- France
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Postoperative Hypoparathyroidism, Thyroid Neoplasms
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy.
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Postoperative Hypoparathyroidism, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NIRAF (NCT04281875)
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Hypocalcemia, Hypoparathyroidism
Vitamin D Levels and Postoperative Hypocalcemia After Total Thyroidectomy
Hypocalcemia is one of the most frequent complications of total thyroidectomy, a procedure used for benign as well as malignant conditions of the thyroid gland. Postoperative hypocalcemia is usually caused by hypoparathyroidism.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Vitamin D Deficiency, Thyroidectomy
- Trial name
- NCT01039714
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypoparathyroidism
Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy
The main objective of this study is to establish an optimal threshold Early parathormon (PTH) assay in order to exclude hypoparathyroidism , that is to say to obtain a negative predictive value of hypoparathyroidism highest…
- Trial name
- NCT02924532
- Testing
- immediate post operative bioassay of Parathyroid Hormone
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Post-Surgical Hypoparathyroidism
PTH-independent Effects of Encaleret
Background: Parathyroid glands in the neck make a hormone that keeps blood calcium levels stable. Sometimes these glands are damaged or removed during neck surgery.
- Trial name
- NCT05735015
- Testing
- encaleret
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Hypoparathyroidism Post-surgical
Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism
The aim of this study is to investigate the effect of daily treatment with Indapamide for 14 days on urinary calcium excretion in patients with post surgical hypoparathyroidisme.
- Trial name
- HYPOCARE treat (NCT07034677)
- Testing
- Indapamide 1.5 MG SR
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Lars Rejnmark
Endocrine Procedural Complications, Thyroid
Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy
The goal of this study is to evaluate the role of intraoperative continous and intermittent neuromonitoring and intraoperative parathormone (PTH) to predict postoperative nerve morbidity and hypocalcemia.
- Conditions
- Endocrine Procedural Complications, Thyroid, Parathyroid; Deficiency, Laryngeal Injury
- Trial name
- PARACAL (NCT03309384)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Central Hospital, Nancy, France
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Transient Hypoparathyroidism
Steroids in the Postoperative Transient Hypoparathyroidism Total Thyroidectomy
The incidence of thyroid cancer (TC) has increased exponentially worldwide. The increase in diagnosed cases brings about an increase in the number of surgeries performed on the thyroid gland, especially total thyroidectomy (TT)…
- Trial name
- Corthyroid (NCT02652884)
- Testing
- phosphate and betamethasone acetate, 2 mL., saline 0.9% NaCl
- Where
- Argentina
- Volunteers
- 110 people
- Sponsor
- Hospital Italiano de Buenos Aires
Post-Surgical Hypoparathyroidism
Risk Factors for Hypoparathyroidism Following Thyroidectomy
The goal of this observational study is to identify the risk factors for post-thyroidectomy hypoparathyroidism in Estonia and to determine whether the magnesium level plays a significant role in the development of…
- Trial name
- NCT07582562
- Where
- 2 sites in Estonia
- Volunteers
- 300 people
- Sponsor
- Tartu University Hospital
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Postoperative Hypoparathyroidism, Thyroid Disease
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Postoperative Hypoparathyroidism, Thyroid Disease, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT05579782
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Hypocalcemia, Vitamin D Deficiency
The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients.
Glucocorticoids are well known for their analgesic, anti-inflammatory, immunomodulatory and anti-emetic effects. Recovery time after thyroid surgery may depend on several factors, such as postoperative pain, nausea and vomiting…
- Conditions
- Hypocalcemia, Vitamin D Deficiency, Postoperative Complications, Postoperative Nausea
- Trial name
- Dexa (NCT04412694)
- Testing
- Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland)., Preoparative blood laboratory tests, Postoperative laboratory blood tests at 6 hour
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Thyroid, Parathyroid; Deficiency
Does Indocyanine Imaging Scoring Predicts Postoperative Parathormone Levels at 24 Hours After Total Thyroidectomy
The aim of the present study is to evaluate the prognostic value of intra-operative indocyanine staining scoring concerning 24 hours post-operative PTH levels and the possible advantages that its' use can give in terms of…
- Trial name
- ICGPREDICT (NCT03910049)
- Testing
- Indocyanine Green
- Where
- 2 sites in Greece
- Volunteers
- 60 people
- Sponsor
- Aristotle University Of Thessaloniki