Clinical trials: Postoperative Edema and Pain
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Post-operative Inflammation Post-operative Pain Post-operative Swelling (Edema)
Efficacy of Oral Serratiopaptidase Vs Dexamethasone on Post-Operative Inflammation After Exodontia. An Experience at Tertiary Care Hospital Karachi Pakistan.
Background and Rationale Exodontia, commonly referred to as tooth extraction, is one of the frequently performed procedures in dental and oral surgical practice.
- Trial name
- EOSVDPIAEAETCH (NCT07785596)
- Testing
- Arm 1:Serratiopeptidase Arm 2: Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Kharadar General Hospital
Postoperative Edema and Pain
Third Molar Extraction and Pulsed Electromagnetic FieldTherapy
This study is a prospective, randomized, double-blinded, controlled, clinical trial that evaluates the efficacy of using PEMF in the postoperative period in decreasing swelling and pain after extraction of impacted third molars.
- Trial name
- PEMF (NCT02376946)
- Testing
- ActiPatch(TM)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Tufts University
Arnica, Third Molar Extraction
Efficacy of Arnica Montana in Reducing Postoperative Edema and Pain
This study is a prospective, randomized, double-blinded, controlled, clinical trial that evaluates the efficacy of using high potency homeopathic Arnica montana (SinEcch™) during the perioperative period for decreasing swelling…
- Trial name
- NCT03944629
- Testing
- SinEcch
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tufts University
Trismus, Edema
Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surgery
The objective of this case-control intervention study is to explore the effectiveness of Concentrated Growth Factor (CGF) and Advanced Platelet Rich Fibrin (A-PRF) on Pain, Edema and Trismus After Impacted Lower Third Molar…
- Conditions
- Trismus, Edema, Pain, Post-Op Complication
- Trial name
- NCT03690167
- Testing
- Concentrated Growth Factor (CGF), Advanced Platelet Rich Fibrin (A-PRF), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Damla Torul
Tooth Extraction, Molar, Third
Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars
The aim of this study was to compare the effect of acupuncture and placebo acupuncture for the control of pain, edema, and trismus following the extraction of third molars and control of preoperative anxiety.
- Conditions
- Tooth Extraction, Molar, Third, Pain, Postoperative, Trismus
- Trial name
- NCT03545022
- Testing
- Acupuncture
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Post Operative Pain, Acute
Saline At Different Temperatures After 3rd Molar Surgery
This double-blind, single-center, split-mouth, randomized prospective clinical trial was conducted among 48 systemically and periodontally healthy patients who had bilaterally asymptomatic mandibular third molars.
- Trial name
- NCT06741696
- Testing
- Surgical extraction, saline irrigations
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Postoperative Pain, Edema
Effects of Sterile Kinesio Tape on Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction (ACLR) is a surgical tissue graft replacement of the anterior cruciate ligament, located in the knee, to restore its function after an injury.
- Trial name
- NCT04873921
- Testing
- sterile kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Baskent University
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Third Molar Surgery
Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative…
- Trial name
- NCT04200885
- Testing
- Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Tooth, Impacted, Tooth Diseases
Evaluation of the Effects of Mefenamic Acid and Dexketoprofen on Postoperative Wisdom Dental Surgery
This study was administered to 22 female and 8 male patients. Patients with impacted wisdom teeth on both sides of the mandible were selected.
- Trial name
- NCT06280014
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Molar, Third, Third Molar Surgery
3D Evaluation of Postoperative Edema After Third Molar Surgery
Surgical removal of third molars is recognized as one of the most frequent procedures performed in oral surgery. Literature is rich in studies attempting to demonstrate the benefit of corticosteroids in third molar surgery…
- Conditions
- Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative
- Trial name
- NCT05941130
- Testing
- Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Age-related Macular Degeneration, Diabetic Macular Edema
Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections
The specific aims of this study are to compare patient experience with and without a proparacaine drop after povidone iodine.
- Conditions
- Age-related Macular Degeneration, Diabetic Macular Edema, Injection Site, Injection Site Infection
- Trial name
- NCT02951351
- Testing
- Proparacaine, Conjunctival culture
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Impacted Third Molar Tooth
Evaluation of the Efficacy of Polybutester Suture on Postoperative Complications in Lower Impacted Third Molar Surgery
This study aimed to evaluate the efficacy of polybutester sutures on postoperative complications in lower impacted third molar surgery.
- Trial name
- NCT05679973
- Testing
- Polybutester suture, Polypropylene suture
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Molar, Third, Photobiomodulation
Preventive Effect of Photobiomodulation in the Postoperative Period of Extractions of Retained Lower Third Molars
Third molar extraction is one of the most performed surgical procedures in Dentistry. A comfortable postoperative period and rapid return to daily activities increase the need to control the inflammatory response and its signs…
- Trial name
- NCT05924191
- Testing
- Photobiomodulation, Simulation Photobiomodulation, Corticosteroid
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Alveolar Osteitis, Dry Socket
Antibiotic Efficacy in Third Molar Surgery
Despite over 50 years of antibiotic use and multiple clinical investigations (>50), no definitive studies exist to confirm or refute the use of systemic antibiotics to prevent postoperative inflammatory complications after third…
- Conditions
- Alveolar Osteitis, Dry Socket, Infection
- Trial name
- NCT00118820
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Impacted Mandibular Third Molar Extraction, Postoperative Pain Control
Evaluation of Corticosteroid Administration Following Impacted Third Molar Surgery Using 3-Dimensional Facial Analysis
The purpose of this prospective, randomized, controlled, single-blind clinical trial is to compare the efficacy of local submucosal administration of dexamethasone versus methylprednisolone on postoperative morbidity following…
- Conditions
- Impacted Mandibular Third Molar Extraction, Postoperative Pain Control, Postoperative Edema and Pain
- Trial name
- NCT07628166
- Testing
- Surgical Extraction of Impacted Mandibular Third Molar, methylprednisolone sodium succinate, Dexamethasone Sodium Phosphate Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Irfan Üstündağ
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Impacted Third Molar Tooth
The Effect of Saline Irrigation at Different Temperatures on Pain, Edema, and Trismus After Impacted Third Molar Surgery
Third molar surgery is one of the most common procedures in oral surgery and the most common postoperative complications are swelling, pain, and trismus.
- Trial name
- NCT05170516
- Testing
- 4 °C colled saline irrigation, 10 °C cooled saline irrigation, Room temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Trakya University