Clinical trials: Postoperative Anemia
Blood Transfusion, Orthopedic Procedures
A Study to Determine the Safety of Epoetin Alfa and Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients After Major Orthopedic Surgery.
The purpose of this study is to determine the safety of epoetin alfa and to determine the effectiveness of epoetin alfa in reducing the need for blood transfusions after major orthopedic surgery.
- Conditions
- Blood Transfusion, Orthopedic Procedures, Anemia
- Trial name
- NCT00270036
- Testing
- epoetin alfa
- Volunteers
- 1 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Postoperative Hemorrhage, Postoperative Anemia
Autologous Whole Blood Management for Transfusion Reduction in Adult Cardiac Surgery Patients
The goal of this pilot trial is to test a protocol for a planned Canada-wide clinical trial looking at whether or not the use of a patients own blood works as good as the current standard of care using donated blood products to…
- Conditions
- Postoperative Hemorrhage, Postoperative Anemia, Postoperative Blood Loss
- Trial name
- NCT05889494
- Testing
- Autologous Whole Blood Management, Standard Care involving allogenic and/or derivative transfusion.
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anemia, Iron Deficiencies
Postoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery
Postoperative anemia is highly prevalent among patients undergoing cardiac surgery and is associated with delayed functional recovery, increased morbidity, and impaired long-term outcomes.
- Conditions
- Anemia, Iron Deficiencies, Iron Deficiency Anemia, Cardiac Surgery
- Trial name
- NCT07238972
- Testing
- Ferric derisomaltose
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
IDA in the Post-bariatric Surgical Patient
Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient
The aim of the study is to compare two accepted treatments for iron deficiency anemia (oral ferrous sulfate and intravenous ferumoxytol) for efficacy and speed of response in the treatment of iron deficiency anemia (IDA) in the…
- Trial name
- NCT03777514
- Testing
- Ferumoxytol, Ferrous sulfate, Oral vitamin C
- Sponsor
- Johns Hopkins University
Anaemia
Oral and Intravenous Iron in Patients Postoperative Cardiovascular Surgery Under Extracorporeal Circulation
Anaemia is a common postoperative problem of cardiovascular surgery after cardiopulmonary bypass (CPB). Because of this the need for hemoderived blood transfusions is high.
- Trial name
- NCT01078818
- Testing
- IV trivalent saccharose hydroxide ferrous, Oral ferrous fumarate
- Where
- Spain
- Volunteers
- 159 people
- Sponsor
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Iron Deficiency Anemia
Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients
Postoperative anemia is common in cardiac surgery with cardiopulmonary bypass. Iron deficiency delays the recovery from postoperative anemia and may negatively affect the postoperative trajectory of cardiac surgery patients.
- Trial name
- AGE-ANEMIA (NCT04913649)
- Testing
- Ferric Derisomaltose 100 MG/ML, Sodium chloride
- Where
- 2 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- dr. P. Noordzij
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis
Kids With Iron Deficiency and Scoliosis
This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and…
- Conditions
- Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies
- Trial name
- KIDS (NCT06042699)
- Testing
- Oral ferrous sulfate
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Columbia University
Total Knee Arthroplasty
Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia
This study is a randomized, placebo-controlled, multicenter research design to investigate the effectiveness and safety of a single-dose intravenous iron combined with HuEPO hematopoietic mobilization before surgery in patients…
- Trial name
- Hematoboost (NCT05911438)
- Testing
- Ferric Derisomaltose Injection (Monoferric) and Human Erythropoietin Injection (EPIAO), Basic Treatment
- Where
- China
- Volunteers
- 419 people
- Sponsor
- West China Hospital
Atherosclerosis, Anemia
The Transfusion Triggers in Vascular Surgery Trial
BACKGROUND Vascular surgical patients often receive red blood cell (RBC) transfusions in the peri-operative period RBC transfusion may lead to improved outcome but on the other hand the intervention may be harmful Danish Health…
- Conditions
- Atherosclerosis, Anemia, Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
- Trial name
- TV (NCT02465125)
- Testing
- red blood cell transfusion
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Naestved Hospital
Anemia, Surgery
Anemia and Red Blood Cells Transfusion in Oncological Surgery
Oncologic patients experience anemia and anemia is associated with poor prognosis. Transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical…
- Conditions
- Anemia, Surgery, Oncology
- Trial name
- IMPACT (NCT04101240)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Postoperative Anemia, Knee Osteoarthritis
Effect of Postoperative Ferric Carboxymaltose
The primary purpose of this study is to evaluate the safety and efficacy of postoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561480
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Heart; Dysfunction Postoperative, Cardiac Surgery, Anemia, Iron-Deficiency
Pre-operative Treatment With Erythropoietin and Iron Supplement in Cardiac Surgery
Pre-treatment of patients with erythropoietin subcutaneously and iron supplement intravenously, in order to create a clinical pathway to minimize transfusion of red blood cells in a selected group of cardiac patients with an…
- Trial name
- NCT02210949
- Testing
- Erythropoietin subcutaneously and Iron intravenously
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Cardiac Surgical Procedures, Blood Transfusion
Systematic Intraoperative Cell Salvage in On-Pump Cardiac Surgery Within a Mature Patient Blood Management Programme
The goal of this observational study is to learn if cell salvage lowers the need for donor blood in adults having planned heart surgery with a heart-lung machine.
- Conditions
- Cardiac Surgical Procedures, Blood Transfusion, Anemia, Postoperative Hemorrhage
- Trial name
- SPARE (NCT07922486)
- Testing
- Systematic intraoperative cell salvage
- Where
- Portugal
- Volunteers
- 657 people
- Sponsor
- Aveiro University
Transfusions, Cystectomy
Robot-assisted Cystectomies With Regard to Blood Loss, Pain and Transfusions.
What influence does robot-assisted surgical treatment in the sense of a radical cystectomy and possibly bladder reconstruction have on blood loss, pain and transfusion requirements? We intend to conduct a corresponding…
- Conditions
- Transfusions, Cystectomy, Blood Loss Requiring Transfusion, Anaemia
- Trial name
- NCT07008261
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Goethe University
Hip Fracture, Anemia
Study of the Effect of Tranexamic Acid Administered to Patients With Hip Fractures. Can Blood Loss be Reduced?
The effect of Tranexamic acid on blood loss, hemoglobin and transfusions in patients with pertrochanteric hip fractures. Tranexamic acid is a well known drug used in many types of surgery.
- Trial name
- NCT01535781
- Testing
- Tranexamic Acid
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Hvidovre University Hospital
Arthroplasty, Hip
Liberal Versus Restrictive Transfusion During Symptomatic Moderate Anemia After Hip Arthroplasty
The purpose of this study is to evaluate the effects of transfusion of red blood cells in treating postoperative dizziness in patients with moderate postoperative anemia after total hip arthroplasty.
- Trial name
- NCT01452581
- Testing
- Red blood cell transfusion, Voluven
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anemia, Cardiac Surgery
Mediation Analysis in Cardiac Surgery
This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery.
- Conditions
- Anemia, Cardiac Surgery, Transfusion, Mediation
- Trial name
- MACS (NCT07092683)
- Testing
- anemia, nonanemia
- Where
- China
- Volunteers
- 13,683 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anemia, Intensive Care
Observational Study of Iron Metabolism in Anemia in ICU and Post-Operative Patients
Anemia in intensive care and post-operative patients is due to both blood loss (leading to iron loss) and inflammation.
- Conditions
- Anemia, Intensive Care, Cardiac Surgery
- Trial name
- FAIRe (NCT00338234)
- Where
- France
- Volunteers
- 153 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate
Tranexamic Acid for Bleeding Reduction During TURP Surgery
Transurethral resection of the prostate (TURP) is commonly performed in elderly patients and may be associated with perioperative bleeding leading to postoperative anemia and delayed recovery.
- Conditions
- Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate, Perioperative Bleeding, Anemia, Postoperative
- Trial name
- TXA-TURP (NCT07460518)
- Testing
- Tranexamic Acid
- Where
- Morocco
- Volunteers
- 80 people
- Sponsor
- Hamza Najout
Anemia, Bariatric Surgery
The Impact of Preoperative Anemia on Postoperative Anemia and Related Nutrient Abnormalities After Bariatric Surgery
This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities 1 year after bariatric surgery.
- Trial name
- NCT06218953
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China-Japan Friendship Hospital