Clinical trials: Postoperative Analgesia After Cesarean Delivery
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Analgesia, Cesarean Section
Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks
The aim of this prospective randomized controlled study is to compare the analgesic efficacy of the ultrasound-guided erector spinae plane block, ultrasound-guided quadratus lumborum plane block, and ultrasound-guided transversus…
- Conditions
- Postoperative Analgesia, Cesarean Section, Erector Spinae Block, Quadratus Lumborum Block
- Trial name
- NCT06451354
- Testing
- Erector spinae plane block (20 ml bupivacaine 0.25% in each side), Posterior Quadratus lumborum plane block (20 ml bupivacaine 0.25% in each side), Lateral Transversus abdominis plane block (20 ml bupivacaine 0.25% in each side)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Kafrelsheikh University
Postoperative Analgesia, Cesarean Delivery
Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control
we aim to compare the analgesic efficacy of two intravenous ketorolac dosing regimens as part of a multimodal analgesic protocol that includes local wound infiltration for postoperative pain management after elective cesarean…
- Conditions
- Postoperative Analgesia, Cesarean Delivery, Ketorolac
- Trial name
- NCT07244757
- Testing
- Ketorolac 30 mg, Ketorolac 15mg
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Cairo University
Cesarean Section
Efficacy of Modified Perichondral Approach Thoracoabdominal Nerve Block For Post Cesarean Section
Cesarean section (CS) is one of the most frequently performed surgical procedures in the World. Moderate to severe postoperative pain occurs in a significant proportion of women after cesarean surgery.
- Trial name
- NCT06078475
- Testing
- Postoperative analgesia management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Opioid-use Disorder, Pain, Postoperative
BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control
This is a randomized, placebo controlled and natural-history controlled trial to investigate the effectiveness of NSS-2 BRIDGE® for postpartum women with AND without opioid use disorder (OUD).
- Trial name
- NCT04365465
- Testing
- NSS-2 Bridge, Inactive NSS-2 Bridge, Active control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Acute Pain Management, Caesarean Section
Transverse Abdominis Plane (TAP) Block Versus Transversalis Fascia Plane Block (TFPB) After Cesarean Delivery
Postoperative analgesia treatment methods are applied to the living in the operating room. It is a routine part of the process of these applications. It is necessary from medical and ethical perspectives.
- Trial name
- NCT06939725
- Testing
- Transversus abdominis plane (TAP) block, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Samsun University
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Cesarean Section, Postoperative Pain
Effect of Guide-Suture-Assisted Modified Fascial Closure on Postoperative Pain and Early Mobilization After Cesarean Section
This randomized controlled trial evaluates whether a guide-suture-assisted modified fascial closure technique reduces postoperative pain and improves early functional recovery compared with classical continuous fascial closure in…
- Trial name
- GSMF-CS (NCT07436520)
- Testing
- Classical continuous fascial closure, Guide-suture-assisted modified fascial closure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Pain, Postoperative
Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section
Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block.
- Trial name
- NCT05671172
- Testing
- Hyaluronidase, Bupivacaine Injection
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Benha University
Analgesia, Post Operative Pain
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.
- Conditions
- Analgesia, Post Operative Pain, Cesarean Section
- Trial name
- NCT06446830
- Testing
- multimodal analgesia and vitamin B, standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Post Operative Pain, Cesarean Section
The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
It will be a prospective observational cohort study. The investigators will compare post-cesarean section recovery in patients receiving intravenous infusion of tramadol-ondansetron versus epidural catheter with infusion of local…
- Conditions
- Post Operative Pain, Cesarean Section, Tramadol, Postoperative Recovery
- Trial name
- TRON (NCT05879536)
- Testing
- Tramadol-ondansetron continuous infusion, Ropivacaine via epidural catheter
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Severe Pain, Cesarean Section Complications
Empowered Relief for Severe Pain After Cesarean Delivery During the Inpatient Period
This pilot feasibility study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain management intervention, to postpartum patients experiencing severe pain following cesarean…
- Conditions
- Severe Pain, Cesarean Section Complications, Postpartum, Chronic Pain
- Trial name
- NCT07832240
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Postoperative Pain
Transversus Abdominis Plane Block vs Continuous Infiltration Wound Catheter for Analgesia After Caesarean Section
Analgesia following surgery associates different intra-venous or oral analgesic drugs and sometimes opioids. To reduce opioid consumption, loco-regional anaesthesia might be administered as a complement.
- Trial name
- TAP-CAT (NCT03102515)
- Testing
- USG-TAP block, CIC
- Volunteers
- 109 people
- Sponsor
- University Hospital, Caen
Postoperative Pain, Postoperative Acute Pain
Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
The goal of this clinical trial is to evaluate whether the addition of a Transversus Abdominis Plane (TAP) block improves postoperative outcomes in women undergoing cesarean section.
- Trial name
- NCT07604376
- Testing
- Postoperative analgesia using TAP block, Ropivacaine 0,2%, volume: 0,4 ml/kg per side, Postoperative pain management using "traditional" analgesia iv regime
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Matild Keresztes
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University