Clinical trials: Postmenopause, active
Obesity, Menopause
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
In postmenopausal women, obesity increases the risk of physical function decline, premature aging, and vascular dysfunction. Semaglutide and tirzepatide are potent obesity medications.
- Trial name
- NCT07057310
- Testing
- semaglutide or tirzepatide, Lifestyle modification intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Postmenopausal Symptoms, Telerehabilitation
Relaxation Training Via Tele-Rehabilitation in Postmenopausal Women
Menopause is associated with various physiological and psychological changes that may adversely affect women's quality of life. Menopausal symptoms, sleep disturbances, and fatigue are among the most common complaints during the…
- Conditions
- Postmenopausal Symptoms, Telerehabilitation, Relaxation Training, Menopause
- Trial name
- NCT07737691
- Testing
- Relaxation Training Delivered via Tele-Rehabilitation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Perimenopause, Postmenopause
The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial
This randomized controlled study will examine whether two different forms of structured health information-seeking education can help women in perimenopause or postmenopause use online health information more effectively.
- Conditions
- Perimenopause, Postmenopause, Cyberchondria, E-Health Literacy
- Trial name
- NCT07834216
- Testing
- Video-Based Health Information-Seeking Education, Pecha Kucha-Based Health Information-Seeking Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Osteopenia
AI-Supported Mobile High-Impact and Strengthening Exercise Program in Postmenopausal Women With Low Bone Density
Low bone mineral density after menopause increases the risk of osteoporosis and fractures, and regular exercise can help preserve bone health. However, adherence to home exercise programs is often low.
- Trial name
- NCT07918716
- Testing
- AI-Supported Mobile Health Application, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University
Postmenopausal Period, Vaginal Atrophy
Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
The aim of study is characteristic of changes in the vaginal wall after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Vaginal Prolapse
- Trial name
- NCT05335317
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MeLSyTech, Ltd
Postmenopause, Menopausal Complaints
The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women
This trial investigates whether supervised training in combination with hormonal substitution therapy has an impact on body composition, cardiovascular risk, risk for dementia, osteoporosis and insulin sensitivity in…
- Trial name
- OPERATE (NCT05831709)
- Testing
- Exercise program, Hormonal substitution therapy per SOC
- Where
- Belgium
- Volunteers
- 390 people
- Sponsor
- University Hospital, Ghent
Postmenopause, Energy Expenditure
Resting Energy Expenditure in Postmenopausal Women
Obesity and its associated comorbidities are rising at an alarming rate, particularly among postmenopausal women. Menopause, characterized by a decline in estradiol and progesterone levels, is often accompanied by weight gain.
- Conditions
- Postmenopause, Energy Expenditure, Hormone Replacement Therapy
- Trial name
- MenoBOLISM (NCT06905886)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Menopause, Perimenopause
Hop Extract Versus Soy Isoflavone Extract for Menopausal Symptoms (HOPES)
HOPES (Hops On Psychological and Estrogenic Symptoms in Menopause) is a randomized, double-blind, active-controlled nutritional intervention study in 120 peri- and postmenopausal women aged 45 to 60 years with moderate to severe…
- Conditions
- Menopause, Perimenopause, Postmenopause
- Trial name
- HOPES (NCT07904390)
- Testing
- Full Spectrum hop extract (MENODUO FullSpectrum), Soy isoflavone extract
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Menoclinica by Palacios
Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms
LASER and Radiofrequency and Genitourinary Syndrome of Menopause
This is a randomized controlled trial to evaluate the use of LASER, Micro Ablative radiofrequency and topic strogen to treat symptoms of vulvovaginal atrophy of post menopause.
- Conditions
- Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms, Genitourinary Symptoms
- Trial name
- EPMLARF-arm1 (NCT04045379)
- Testing
- LASER, Microablative Radiofrequency, Estriol
- Where
- Brazil
- Volunteers
- 195 people
- Sponsor
- Federal University of São Paulo
Hormone Therapy
Hormone Therapy and Angiotensin-Dependent Arterial and Renal Vasoconstriction in Humans
1. to investigate the association between route of administration of exogenous estrogen (transdermal vs. oral) and cardiorenal risk in cisgender (gender identity aligning with sex at birth) and transgender (gender identity not…
- Trial name
- NCT05442463
- Testing
- Captopril Tablets, Iohexol
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Postmenopausal Symptoms, Obesity
Exercise Training and Fat Metabolism in Postmenopausal Women
Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synthesis.
- Conditions
- Postmenopausal Symptoms, Obesity, Prediabetic State
- Trial name
- NCT05351476
- Testing
- Resistance Exercise, Endurance Exercise
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida State University
Stress Urinary Incontinence (SUI)
Motor Imagery-Assisted Pelvic Floor Muscle Training for Stress Urinary Incontinence in Postmenopausal Women
This study will evaluate whether adding mental rehearsal of pelvic floor muscle contractions to pelvic floor muscle training improves stress urinary incontinence in postmenopausal women.
- Trial name
- NCT07853755
- Testing
- Pelvic Floor Muscle Training, Pelvic-Floor-Specific Kinesthetic Motor Imagery, Dominant-Hand Kinesthetic Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Menopause, Menopause Hot Flashes
Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women
The menopausal transition is associated with significant hormonal changes that negatively impact many women's quality of life. Vasomotor symptoms, sleep disturbances, mood changes, and genitourinary symptoms are frequently…
- Conditions
- Menopause, Menopause Hot Flashes, Overweight , Obesity, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07822230
- Testing
- Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population in printed material and 5 in-person and virtual meetings, Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population only in printed material
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Post Menopausal Women
The Role of Diet Quality in Sleep Among Women in Postmenopause
This single-center, randomized controlled trial with parallel groups, consists of an intensive nutritional intervention based on a high-fiber Mediterranean diet (target intake: 30-35 g/day of dietary fiber), which will be…
- Trial name
- EMILE (NCT07918287)
- Testing
- Intensive High-Fiber Mediterranean Diet Counseling, Low-Intensity Mediterranean Diet Counseling
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Metabolic Syndrome, Postmenopausal Symptoms
Circadian Rhythms in Postmenopausal Women
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms…
- Trial name
- NCT04893226
- Testing
- Time-Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Postmenopausal Period, Menopausal Symptoms
Effects of Mindfulness-Based Self-Efficacy Development Program on Postmenopausal Women
The aim of this randomized controlled clinical trial is to evaluate the effects of a mindfulness-based self-efficacy development program on menopausal symptoms and quality of life in postmenopausal women.
- Conditions
- Postmenopausal Period, Menopausal Symptoms, Quality of Life, Stress Management
- Trial name
- MOPKA (NCT07034885)
- Testing
- Mindfulness-Based Self-Efficacy Development Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Nurcan Gökgöz
Genitourinary Syndrome of Menopause
Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxygenation Device - VNOD) in the Improvement of Symptoms Related to Genitourinary Syndrome of Menopause in Women with Natural and Oncological Postmenopause: Open-Label, Single-Center, Randomize
The Caress study is a single-center, open-label, randomized controlled trial (RCT) evaluating the efficacy of a combined treatment using topical hyaluronic acid and high-concentration oxygen therapy (Vaginal Natural Oxygenation…
- Trial name
- Caress (NCT06879938)
- Testing
- High-concentration vaginal oxygen therapy (Caress Flow) with topical hyaluronic acid, hyaluronic acid-based gel (Hydeal-D®)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Postmenopausal Period, Postmenopausal Women
AI-Assisted Relaxation and Breathing Training in Postmenopausal Women
This study aims to evaluate the effectiveness of relaxation and breathing training delivered by a physiotherapist and by an artificial intelligence-assisted system in postmenopausal women with non-specific chronic musculoskeletal…
- Trial name
- NCT07302750
- Testing
- Physiotherapist-Guided Relaxation and Breathing Training, Artificial Intelligence-Assisted Relaxation and Breathing Training, Control Group - No Structured Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Glucose Monitoring, Continuous, Whole Body Protein Metabolism
Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women
The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle…
- Conditions
- Glucose Monitoring, Continuous, Whole Body Protein Metabolism, Peri-menopausal Women, Post-menopause
- Trial name
- NCT07402382
- Testing
- Amylopectin-chromium blend, Concentrated Amylopectin-chromium blend
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutrition 21, Inc.
Urinary Incontinence (UI), Postmenopause
The Effect of Sujok Therapy on Urinary Incontinence and Quality of Life in Postmenopausal Women
This study aims to investigate the effect of Su Jok therapy, a complementary medicine practice, on urinary incontinence and quality of life among postmenopausal women.
- Trial name
- NCT06951022
- Testing
- Sujok therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University