Clinical trials: Post-stroke Depression, open to volunteers
Stroke, Post-stroke Depression
The Research Team Aims to Elucidate the Impact of ITBS (intermittent Theta Burst Stimulation) on the HPA Axis and Post-stroke Negative Emotions/depression by Conducting Human Experiments That Target Various Brain Regions.
The project team will categorize stroke patients into three groups receiving iTBS stimulation targeting distinct brain regions: the cerebellum, the dorsolateral prefrontal cortex (DLPFC), and the primary motor cortex (M1), with…
- Trial name
- NCT06899893
- Testing
- iTBS
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stroke, Stress, Psychological
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of an psychotherapeutic frame…
- Conditions
- Stroke, Stress, Psychological, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06633146
- Testing
- Therapies in nature
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Post-stroke Depression
Investigating How the RECT Impacts Brain Functional States Through the ACC-cerebellar Loop
Experiment1: Using a brain EEG-TMS combined system, researchers aim to investigate the impact of the rostral anterior cingulate cortexr (rACC)-engaging cognitive task (RECT) combined single-pulse TMS magnetic stimulation on theta…
- Trial name
- NCT06912191
- Testing
- Left cerebellar TMS stimulation combined with the RECT task, Right cerebellar TMS stimulation combined with the RECT task, Midline cerebellar TMS stimulation combined with the RECT task
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Post-stroke Depression
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
Experiment 1: Utilizing a transcranial magnetic stimulation-electroencephalography/functional near-infrared spectroscopy system, the investigators aim to determine whether transcranial magnetic stimulation of the cerebellum can…
- Trial name
- NCT06860451
- Testing
- TMS
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stroke, Post-stroke Depression
Effects of Robotic Rehabilitation on Quality of Life, Mood, and Fatigue After Stroke
Stroke is a major cause of long-term disability and is often associated with reduced quality of life, depression, anxiety, and fatigue.
- Conditions
- Stroke, Post-stroke Depression, Post-stroke Anxiety, Post-stroke Fatigue
- Trial name
- NCT07203937
- Testing
- RoboGait® Robotic Gait Training, Treadmill Walking Training
- Volunteers
- 36 people
- Sponsor
- Meltem Gunes Akinci
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Ischemic Stroke, Acute
A Multicenter Study Based on Multi-omics Analysis to Predict the Early Prognosis and Recurrence Risk of Acute Ischemic Stroke
Through a multicenter prospective AIS cohort study, we analyze the potential association of human proteome, microbiome and metabolome alterations with AIS prognosis, searching for key proteins, differential organisms and…
- Trial name
- NCT06584565
- Testing
- microbiome; metabolomics; proteomics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cerebral Apoplexy, Depression Anxiety Disorder
Efficacy and Safety Evaluation of Remote Ischemic Adaptation ( Intermittent Pressure Stimulation ) in the Treatment of Insomnia After Stroke
The incidence of post-stroke depression is high, which will affect the rehabilitation of neurological function, damage cognitive function, and increase the risk of subsequent stroke recurrence.
- Conditions
- Cerebral Apoplexy, Depression Anxiety Disorder, Cerebrovascular Disease
- Trial name
- NCT07401784
- Testing
- Automatic ischemic preconditioning therapeutic apparatus
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Post Stroke, Anxiety
Therapeutic Music Listening in Post Stroke Patients.
Numerous studies have highlighted how individualized music listening favors motor, cognitive, and emotional recovery in post-stroke patients, stimulating neuroplasticity and cerebral connectivity.
- Conditions
- Post Stroke, Anxiety, Depression
- Trial name
- ML4STROKE (NCT07432204)
- Testing
- Music intervention, Control group
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Post-stroke Depression, Remote Ischemic Conditioning
Efficacy of Remote Ischemic Conditioning in Preventing Post-Stroke Depression
Post-stroke depression (PSD) is characterized primarily by low mood and loss of interest following a stroke. It is one of the most common and serious complications of stroke, with an incidence of 11% to 41% within two years…
- Trial name
- NCT06920706
- Testing
- RIC
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Xuanwu Hospital, Beijing
Post Stroke Depression
Hyperbaric Oxygen Therapy for Persistent Post Stroke Depression
The study evaluates the effect of HBOT on depression in patients suffering from persistent symptoms of post stroke depression (PSD) in an double blind sham control study.
- Trial name
- NCT07423273
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Assaf-Harofeh Medical Center
Post-stroke Depression
A Study on the Preventive Effect of Electroacupuncture Combined With Dexmedetomidine in Post-stroke Depression
Post-stroke depression (PSD) is a common neuropsychiatric complication following stroke and has emerged as a major public health concern due to its adverse impact on post-stroke prognosis.
- Trial name
- NCT07739329
- Testing
- Dexmedetomidine, Electropuncture, Normal Saline (NS)
- Volunteers
- 231 people
- Sponsor
- Min Su
Stroke, Depression - Major Depressive Disorder
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in…
- Conditions
- Stroke, Depression - Major Depressive Disorder, Walking Impairment
- Trial name
- RESTORATION (NCT07050355)
- Testing
- rTMS, AEx
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Medical University of South Carolina
Post-stroke Depression, Subthreshold Depression
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors
The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke…
- Trial name
- LIVE-WEL (NCT06864715)
- Testing
- Tele-delivered Behavioral Activation by lay counselors after Stroke (Tele-BA-S), Treatment as Usual
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Stroke, Depressive Symptoms
Morning Activation to Improve Mood After Stroke
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a six-week behavioral intervention designed to improve mood and daily functioning in adults who have experienced a stroke and report…
- Trial name
- NCT07719517
- Testing
- Morning Activation Program, Health Education Program
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Post Stroke
An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients
The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage…
- Trial name
- NCT07691411
- Testing
- Ecological Momentary Assessment based Self-management Program
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Ischemia Stroke, Post-stroke Depression
Nursing Health Education to Improve Functionality and Quality of Life After Ischemic Stroke
This study is titled "Effect of a Nursing Intervention Based on Health Education on Functionality, Depression Symptoms, and Quality of Life in Patients with Ischemic Stroke." It is a quasi-experimental, longitudinal, prospective…
- Conditions
- Ischemia Stroke, Post-stroke Depression, Post-stroke, Quality of Life
- Trial name
- NCT07343284
- Testing
- Health education Program
- Volunteers
- 70 people
- Sponsor
- University of Santiago de Compostela
Post Stroke Depression, Post Stroke Fatigue
The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.
Background: Light is the most important regulator of circadian rhythm. Naturalistic light, which contains the spectrum of sunlight throughout the day, has been shown to have a positive impact on mental states such as depression…
- Conditions
- Post Stroke Depression, Post Stroke Fatigue, Circadian Dysregulation, Stroke
- Trial name
- NCT06922409
- Testing
- Naturalistic Light Intervention
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Apathy, Stroke
Accelerated rTMS vs. Sham for Stroke Apathy
Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them.
- Conditions
- Apathy, Stroke, Stroke Sequelae, Stroke/Brain Attack
- Trial name
- NCT07113067
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active), Brainsight Neuronavigation System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina