Clinical trials: Post-mastectomy Pain Syndrome
Post-mastectomy Pain Syndrome
Efficacy of Glucose in Serratus Anterior Plane Block to Reduce the Occurrence of Chronic Post-mastectomy Pain
Nearly 50% of patients suffer from chronic pain following breast cancer surgery. Several regional anesthesia techniques, including paravertebral block, erector spinae plane block, pectoral nerves block, and serratus anterior…
- Trial name
- NCT06443619
- Testing
- unilateral USG-deep SAPB with glucose, unilateral USG-deep SAPB without glucose
- Volunteers
- 190 people
- Sponsor
- Mansoura University
Pain Syndrome, Pain
A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome
To learn if using guided imagery and deep breathing techniques can help with pain management in patients who have post-mastectomy pain syndrome.
- Conditions
- Pain Syndrome, Pain, Symptom Management
- Trial name
- NCT05408741
- Testing
- The Intervention Group, The Control Group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Treatment of Postmastectomy Pain Syndrome With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post mastectomy pain syndrome. Half of patients will receive fat grafting and the other half of patients will receive sham.
- Trial name
- NCT03081286
- Testing
- Liposuction, Fat graft
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Axillary Web Syndrome, Post-mastectomy
Effects of Muscle Energy Techniques With and Without Manual Axial Distraction in Post-Mastectomy Patients With Axillary Web Syndrome
This randomized controlled trial aims to evaluate the effects of muscle energy techniques with and without manual axial distraction among post-mastectomy patients with axillary web syndrome.
- Trial name
- MET MAD PM AWS (NCT07266623)
- Testing
- Muscle energy technique + Manual axial distraction, Muscle energy technique
- Volunteers
- 58 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Breast Cancer, Breast Pain
Post Mastectomy Pain Syndrome After Preoperative Stellate Ganglion Block for Breast Cancer Surgeries
This study investigate the effect of pre-operative ultrasound guided stellate ganglion block with local anesthetic on the frequency of neuropathic pain syndromes in the first 6-month post cancer breast surgeries with axillary…
- Trial name
- NCT04238377
- Testing
- Stellate Ganglion Block, Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Chronic Pain
Does Pecs II Block Reduce the Incidence of Post Mastectomy Pain Syndrome (PMPS)? A Cross Sectional Study
Post mastectomy pain syndrome (PMPS) is a chronic pain condition that develops after breast cancer surgery. The objective of this study was to determine if Pecs II block administered prior to general anesthesia (GA) reduced the…
- Trial name
- PMPS (NCT04095897)
- Testing
- Pecs II Block
- Where
- Malaysia
- Volunteers
- 288 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Amantadine, Duloxetine
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
- Conditions
- Amantadine, Duloxetine, Pregabalin, Mastectomy
- Trial name
- NCT07421427
- Testing
- Pregabalin, Pregabalin + Amantadine, Pregabalin + Duloxetine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Prevention of Post Mastectomy With Intraoperative Ketamine
Aim 1: To determine the effectiveness of perioperatively administered ketamine to decrease acute and persistent postmastectomy pain (PPMP).
- Trial name
- NCT03090776
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Brigham and Women's Hospital
Post-mastectomy Pain Syndrome, Breast Cancer
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months…
- Conditions
- Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04874038
- Testing
- Lidocaine 20mg/ml
- Where
- 17 sites in Canada, Nepal and 1 more
- Volunteers
- 1,604 people
- Sponsor
- University Health Network, Toronto
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Post-Mastectomy Chronic Pain Syndrome
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-mastectomy pain due to nerve injury leads to long-term opioid use and diminished quality-of-life. The investigators on this study will evaluate the regenerative peripheral nerve interface (RPNI), a novel surgical approach to…
- Trial name
- RPNI (NCT04530526)
- Testing
- Regenerative Peripheral Nerve Interface
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan Rogel Cancer Center
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Stellate Ganglion, Radiofrequency Ablation
Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
The aim of this study is to evaluate the efficacy of the combination of Ultra Sound (US) guided radiofrequency stellate ganglion block (SGB) and radiofrequency Thoracic Paravertebral block (TPVB) comparing to US-guided SGB or…
- Conditions
- Stellate Ganglion, Radiofrequency Ablation, Complex Regional Pain Syndromes, Mastectomy
- Trial name
- NCT06033456
- Testing
- Radiofrequency stellate ganglion block using ultrasound guidance (SGB), Radiofrequency thoracic (T2, T3) paravertebral block under fluoroscopic guidance (TPVB), Combined radiofrequency of stellate ganglion block plus thoracic T2, T3 paravertebral block
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- National Cancer Institute, Egypt
Post-mastectomy Pain Syndrome
The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery.
Breast cancer is the most common malignancy among females. Nearly 40% of breast surgery patients experience moderate to severe acute postoperative pain, with severe pain persisting for more than 6 months in almost 20-50% of…
- Trial name
- NCT05935059
- Testing
- Pregabalin, Tianeptine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Breast Neoplasms
Combined Intra-articular Shoulder Injection and Stellate Ganglion Block in Chronic Post-mastectomy Shoulder Pain
Background and Purpose: Adhesive capsulitis of the shoulder is commonly found in patients after breast cancer treatment. We aimed to determine the effectiveness of combined shoulder joint intra-articular injection of platelet…
- Trial name
- NCT03586154
- Testing
- Platelet rich plasma, ketamine and bupivacaine injection
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Breast, Mastectomy, Segmental
Post-Breast Procedure Pain Syndrome Study
The purpose of this study is to better understand and characterize the pain that some patients experience after undergoing various breast surgeries, including breast biopsy, lumpectomy, mastectomy, mastectomy with reconstruction…
- Trial name
- NCT01114984
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Post-Mastectomy Neuropathic Pain Syndrome
Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome
The goal of this phase II clinical trial is to study the effectiveness of a treatment with Serratus Plane Block (SPB) or Botox-A in comparison with capsaicin for the control of chronic neuropathic pain of post-mastectomy syndrom…
- Trial name
- SERCABOT (NCT06807164)
- Testing
- Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A
- Where
- France
- Sponsor
- Centre Oscar Lambret
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency for Chronic Post-mastectomy Pain: is it Better to Target Intercostal Nerves or Corresponding Dorsal Root Ganglia?
neuropathic pain can occur following any surgical procedure on the breast ..
- Trial name
- NCT03374423
- Testing
- radiofrequency
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post-Mastectomy Chronic Pain Syndrome
Dex & Mastectomy Pain
Chronic post-surgical pain is a common complication following mastectomy and represents a significant source of long-term morbidity.
- Trial name
- NCT07556952
- Testing
- Dexamethasone (intravenous), Normal Saline (0.9% NaCl)
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre