Clinical trials: Post-mastectomy Pain Syndrome
Breast Cancer, Post-mastectomy Pain Syndrome
Incidence and Factors Affecting the Development and Outcome of Post Mastectomy Pain Syndrome
This multi-centre, prospective study aims to obtain a precise estimate of the local incidence of PMPS and identify biopsychosocial risk factors contributing to the development of PMPS.
- Trial name
- PMPS (NCT04989179)
- Where
- 3 sites in Singapore
- Volunteers
- 220 people
- Sponsor
- Singapore General Hospital
Chronic Pain
Physical Exercise, Motor Activity and Post-mastectomy Pain Syndrome.
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT05713786
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period.
- Conditions
- Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
- Trial name
- NCT03656679
- Testing
- Pectoralis Blockade (PECs), Paravertebral Blockade
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast Cancer
Targeted Nerve Surgery for the Prevention of Post-Mastectomy Pain Syndrome: A Randomized Trial
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain condition often caused by neuroma formation and nerve injury following breast cancer surgery.
- Trial name
- NCT07146009
- Testing
- Nerve Surgery, Standard of Care (Investigator Choice)
- Volunteers
- 60 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Breast, Mastectomy, Segmental
Post-Breast Procedure Pain Syndrome Study
The purpose of this study is to better understand and characterize the pain that some patients experience after undergoing various breast surgeries, including breast biopsy, lumpectomy, mastectomy, mastectomy with reconstruction…
- Trial name
- NCT01114984
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Post-mastectomy Pain Syndrome
Efficacy of Glucose in Serratus Anterior Plane Block to Reduce the Occurrence of Chronic Post-mastectomy Pain
Nearly 50% of patients suffer from chronic pain following breast cancer surgery. Several regional anesthesia techniques, including paravertebral block, erector spinae plane block, pectoral nerves block, and serratus anterior…
- Trial name
- NCT06443619
- Testing
- unilateral USG-deep SAPB with glucose, unilateral USG-deep SAPB without glucose
- Volunteers
- 190 people
- Sponsor
- Mansoura University
Chronic Pain Syndrome
The Analgesic Efficacy Supra-scapular Nerve RF After Breast Surgery
Eighty patients with chronic shoulder pain after breast surgery were allocated randomly into 2 groups; forty patients received fluoroscopically guided supra-scapular nerve pulsed radiofrequency (PRF) followed by injection of…
- Trial name
- NCT03247842
- Testing
- suprascapular nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Post-mastectomy Pain Syndrome
Evaluation and Re-evaluation of Post-mastectomy Pain Syndrome by Breast Cancer EDGE Task Force Outcomes
The purpose of the Breast Cancer EDGE Task Force is to provide physiotherapists with a comprehensive list of outcome measures that can be administered to a selected patient population, to assess post-mastectomy pain syndrome.
- Trial name
- NCT05458154
- Testing
- questionnaires
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Post-Mastectomy Chronic Pain Syndrome
Motor Cortex Versus Insula Stimulation Using Transcranial Current Stimulation on Chronic Post-mastectomy Pain
This study is designed to evaluate the effect of two concentric electrode transcranial direct current stimulation over the primary motor cortex versus insular cortical targets in post mastectomy neuropathic pain.
- Trial name
- NCT05544604
- Testing
- Transcranial direct current stimulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- South Egypt Cancer Institute
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study
Postmastectomy pain syndrome (PMPS) is a neuropathic pain that can follow surgical treatment for breast cancer, The antineuropathic medications (antidepressants and anticonvulsants) are disappointing and have low success rate.
- Trial name
- NCT03494426
- Testing
- radiofrequency thoracic sympathectomy, pregabalin ,tramadol,and tricyclic antidepressants
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Pain Syndrome, Pain, Postoperative
The Impact of Pecs Blocks on Postmastectomy Pain Syndrome
The aim of the present study is to investigate the incidence of chronic pain following breast cancer surgery in Cyprus, discover its associated risk factors and explore the impact of Pecs Blocks on the appearance of post…
- Conditions
- Pain Syndrome, Pain, Postoperative, Chronic Pain, Breast Cancer
- Trial name
- NCT04586751
- Testing
- Pecs block, no Pecs block
- Where
- 3 sites in Cyprus, Greece
- Volunteers
- 64 people
- Sponsor
- Aretaieion University Hospital
Post Mastectomy Pain Syndrome, After Breast Surgery
Stellate Ganglionic Block Versus Stellate Ganglionic Block Plus Pecs II Block for Mastectomy Pain
Post mastectomy pain syndrome result from surgical damage to the intercostobrachial nerve, the lateral cutaneous branch of the second intercostal nerve that is often resected at mastectomy.
- Trial name
- NCT02641951
- Testing
- Stellate ganglionic block, Pecs II block
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Chronic Pain Syndrome
Physical Exercise, Motor Activity on Sleep Disorders in Post-Mastectomy Pain Syndrome
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT06803563
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Gioacchino Calapai
Breast Cancer, Post-mastectomy Pain Syndrome
Erector Spinae Plane Block Versus Serratus Anterior Block on Post Mastectomy Pain Syndrome
Breast cancer is the most common malignancy among females. Nearly 40-60% of breast surgery patients experience severe acute postoperative pain, with severe pain persisting for 6-12 months in almost 20-50% of patients (post…
- Conditions
- Breast Cancer, Post-mastectomy Pain Syndrome, Acute Pain
- Trial name
- NCT05201963
- Testing
- Serratus Anterior Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- National Cancer Institute, Egypt
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Cryoablation for Post Mastectomy Pain Syndrome
This is a prospective, randomized, parallel-group, treatment control trial with cross-over options performed at four sites. The purpose of this study is to assess the efficacy and safety of cryoablation therapy for the treatment…
- Trial name
- NCT03293940
- Testing
- Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency for Chronic Post-mastectomy Pain: is it Better to Target Intercostal Nerves or Corresponding Dorsal Root Ganglia?
neuropathic pain can occur following any surgical procedure on the breast ..
- Trial name
- NCT03374423
- Testing
- radiofrequency
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post Mastectomy Pain Syndrome, Chronic Pain Following Surgical Procedure for Cancer
Super-voltage PRF of Stellate Ganglion Versus Super-voltage PRF of T2 T3 Sympathetic Ganglia in Managing PMPS.
The aim of this study is to compare the effectiveness of super-voltage pulsed radiofrequency of stellate ganglion and super-voltage pulsed radiofrequency of T2-T3 sympathetic ganglia in the treatment of postmastectomy pain…
- Trial name
- PMPS PRF (NCT07675096)
- Testing
- Group S : Stellate Ganglion supervoltage pulsed radiofrequency, Group T : T2-T3 chains supervoltage pulsed radiofrequency.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Post-mastectomy Pain Syndrome
The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery.
Breast cancer is the most common malignancy among females. Nearly 40% of breast surgery patients experience moderate to severe acute postoperative pain, with severe pain persisting for more than 6 months in almost 20-50% of…
- Trial name
- NCT05935059
- Testing
- Pregabalin, Tianeptine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt