Clinical trials: Post-endoscopic Mucosal Resection of Colon Polyps
Colonic Adenomas
Soft Coagulation for the Prevention of Adenoma Recurrence
Recurrence after endoscopic mucosal resection of laterally spreading lesions (LSL) >= 20mm in size occurs in approximately 20% of cases at surveillance colonoscopy.
- Trial name
- SCAR (NCT01789749)
- Testing
- Snare Tip Soft Coagulation, No Snare Tip Soft Coagulation
- Where
- 4 sites in Australia
- Volunteers
- 455 people
- Sponsor
- Professor Michael Bourke
Gastric Polyps, Intestinal Polyps
Recurrence After Gastric and Intestinal Polyp Resection
This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.
- Conditions
- Gastric Polyps, Intestinal Polyps, Colon Polyps, Colorectal Polyps
- Trial name
- RAGIP (NCT07314554)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LanZhou University
Colonic Polyp
Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.
Cold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized <9 mm.
- Trial name
- NCT05930041
- Testing
- Experimental CSP, Active Comparator HS-EMR
- Where
- Japan
- Volunteers
- 124 people
- Sponsor
- Showa Inan General Hospital
Colonic Adenoma, Colonic Polyp
PROSpective Assessment of Post EmR Recurrence
To prospectively validate the SERT (Sydney EMR Recurrence Tool) scoring system for adenoma recurrence rates around the endoscopic mucosal resection (EMR) scar after wide field-EMR with thermal treatment applied to the defect…
- Trial name
- PROSPER (NCT02957058)
- Testing
- SCAR technique
- Where
- Australia
- Volunteers
- 700 people
- Sponsor
- Western Sydney Local Health District
Colonic Polyp, Gastrointestinal Neoplasms
Clinical Study on Continuous Suture of Endoscopic Mucosal Defects
The use of clips to completely clip mucosal defects after ESD/EMR can reduce postoperative adverse events, but the rate of incomplete mucosal defects closure is high.
- Trial name
- NCT05190042
- Testing
- Cotinuous suture, Clips
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Colonic Polyp, Colonic Neoplasms
Additive Hemostatic Efficacy of EndoClot After EMR or ESD in the Gastrointestinal Tract
The investigators want to verify in a randomised trial, the effectiveness of EndoClotTM in preventing post-procedural bleeding after EMR (Endoscopic Mucosal Resection) or ESD (Endoscopic Submucosal Dissection) for sessile lesions…
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Dysplasia
- Trial name
- NCT02688699
- Testing
- EndoClot
- Volunteers
- 288 people
- Sponsor
- University of Turin, Italy
Wound Endoscopical, Colon, After Polyp Resection, Colon
Efficacy of EndoClot™ Spraying After Endoscopic Resection of Large Colorectal Polyps
The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps.
- Trial name
- EndoClot™ (NCT05029934)
- Testing
- use of EndoClot
- Where
- 5 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Post-endoscopic Mucosal Resection of Colon Polyps
Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods
The purpose of this study is to compare the accuracy of using different endoscopic imaging technique (white light, white light with near focus, narrow band imaging (NBI), NBI with near focus) for detection of residual neoplastic…
- Trial name
- NCT02668198
- Testing
- Olympus CF190 Colonoscope High definition white light, Olympus CF190 Colonoscope White light with near focus, Olympus CF190 Colonoscope Narrow band imaging
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Michael Wallace
Colorectal Cancer, Polyp of Colon
Complete Closure After Endoscopic Mucosal Resection of Large Non-Pedunculated Colorectal Polyps
The goal of this clinical trial is to compare adverse even rates after EMR for large (≥20mm) flat colorectal polyps (so-called laterally spreading lesions, LSLs) when performing complete or no defect closure.
- Trial name
- Closure-RCT (NCT06807073)
- Testing
- Prophylactic defect closure, No prophylactic defect closure
- Where
- Canada
- Volunteers
- 686 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Liver Cirrhosis, Portal Hypertension Related to Cirrhosis
Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension
The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension.
- Conditions
- Liver Cirrhosis, Portal Hypertension Related to Cirrhosis, Polyp of Colon, Polypectomy
- Trial name
- NCT06832826
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Colorectal Neoplasms, Adenoma Colon
Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm
Intensive endoscopic surveillance following piecemeal resection of non-pedunculated colorectal lesions (NPCL) ≥20 mm is the current standard of care, given the high recurrence rate of these lesions (15-30%).
- Conditions
- Colorectal Neoplasms, Adenoma Colon, Colonic Polyps, Serrated Adenoma
- Trial name
- NCT06791616
- Testing
- Colonoscopy
- Volunteers
- 746 people
- Sponsor
- Asociación Española de Gastroenterología
Pain, Endoscopic Mucosal Resection
Prospective Evaluation of Pain Assessment and Management Protocol for Post-procedural Pain After Endoscopic Mucosal Resection of Colonic Polyps >20mm
Endoscopic mucosal resection (EMR) of large (≥20 mm) laterally spreading colonic lesions (LSL) is safe, effective and superior to surgery.
- Trial name
- NCT03471156
- Where
- Australia
- Volunteers
- 325 people
- Sponsor
- Western Sydney Local Health District
Polyp Colorectal, Endoscopic Mucosal Resection
Structured TXI-RDI Integration for Endoscopic Resection
The goal of this clinical research study is to learn whether two advanced imaging tools, called Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), can make the removal of large colon polyps safer…
- Trial name
- STRIkER (NCT07474844)
- Testing
- Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), High Definition White Light Endosocopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin