Clinical trials: Post-bariatric Surgery
Anastomotic Stricture, Morbid Obesity
Study of Proton Pump Inhibitors (PPI) to Prevent Strictures After Gastric Bypass Surgery
The purpose of this study is to determine whether suppressing acid production by administration of daily proton pump inhibitors in the early post-operative period will reduce the gastrojejunal anastomosis stricture rate in…
- Trial name
- NCT00361985
- Testing
- Esomeprazole
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Food Preferences Variations Depending on Bariatric Surgery Status
Pilot Suty of the Assessment of Food Preferences After Bariatric Surgery (BariaTaste Pilot)
More than 50,000 patients in France benefit from bariatric surgery every year. However, nutritional complications (protein malnutrition, hypoglycaemia) are common and primary or secondary weight failures (weight recovery) account…
- Trial name
- NCT03486210
- Testing
- Food preference, Psychological assesment
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Weight Loss
Mother and Child Health Outcomes After Maternal Bariatric Surgery
Childhood obesity has been a growing problem with more than 30% of children between 6 and 19 years old being considered overweight or obese.
- Trial name
- NCT03297307
- Testing
- Presurgical Counseling
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Obesity
Testing the Gravitostat in Humans: the Impact of a Weighted Vest in Patients Post Bariatric Surgery on Fat-free Mass Retention and Weight Loss
The mechanisms regulating fat mass homeostasis are incompletely understood although recent animal and human trials would suggest that there is a leptin independent regulatory pathway which may play a role in weight control and…
- Trial name
- NCT04809129
- Testing
- Weighted vest
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Gallstone Disease, Bariatric Surgery
ABCG8, UGT1A1 and Gallstone Disease After Bariatric Surgery
The goal of this observational genetic case-control study is to learn whether two specific genetic variants in ABCG8 and UGT1A1 are associated with gallstone disease after bariatric surgery.
- Conditions
- Gallstone Disease, Bariatric Surgery, Metabolic Surgery, Cholecystectomy
- Trial name
- NCT07702630
- Testing
- blood sampling
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity, Periodontitis
Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery
The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions.
- Conditions
- Obesity, Periodontitis, Caries, Periapical Lesion
- Trial name
- NCT00531154
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Weight Loss, Bariatric Surgery
Outcomes After Weight Loss Surgery in Low-Risk Patients
The purpose of this research is to determine patient-reported outcomes after weight loss surgery, including changes in health, mood, quality of life, health satisfaction, and emotional health, in low-risk patients.
- Trial name
- NCT05699083
- Testing
- Body Image/Self-Esteem Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Feiz & Associates
Proteinuria
Bariatric Surgery and the Kidney
The purpose of the project is to study the relationship between post-bariatric surgery changes in weight and renal parameters.
- Trial name
- NCT01410994
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obesity
Mindful Construal Diaries: Can the MCD Increase Mindfulness and Mindful Eating in Bariatric Surgery Patients
The study aims to test the Mindful Construal Diary (MCD- a mindful eating intervention) initially developed by Mantzios and Wilson.
- Trial name
- NCT03822481
- Testing
- Mindful Construal Diary
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Birmingham City University
Anesthesia, Analgesia
Patient Reported Outcome After Bariatric Surgery
Prospective association study to analyse patients' outcome after bariatric surgery. Outcome comprises postoperative pain, analgesia, postoperative side-effects, long-lasting pain, patients' impairment in daily living.
- Conditions
- Anesthesia, Analgesia, Bariatric Surgery
- Trial name
- NCT03490630
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Motor Activity, Weight Loss
Effect of a Technology-Based Intervention on Weight Change Post-Bariatric Surgery
The primary aim of this study is to examine the effect of applying a minimal contact technology-based intervention (TECH) at 1-year post-bariatric surgery on weight change compared to Standard Care.
- Trial name
- NCT02867696
- Testing
- Standard Care, Technology-based Intervention (TECH)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Gastric Emptying, Bariatric Surgery
Reference Values for Gastric Emptying Scintigraphy After Bariatric Surgery
Oesophageal and gastric scintigraphy evaluates the function of the gastrointestinal system including variables such as oesophageal transit and gastric emptying (GE). Some variables are known to change after bariatric surgery.
- Trial name
- SCATTER (NCT06391255)
- Testing
- scintigraphy
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Abdominoplasty Surgery
Correlation Between Intra-abdominal Pressure and Diaphragmatic Mobility in Women Submitted to Abdominoplasty After Bariatric Surgery
Background: Plication of the rectus abdominis muscles leads to an increase in intra-abdominal pressure (IAP), which may negatively impact the respiratory system due to its effects on diaphragmatic mobility (DM).
- Trial name
- NCT06648694
- Testing
- Abdominoplasty surgery, Abdominoplasty
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Bariatric Surgery Candidate, Pain, Postoperative
Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery
Laparoscopic bariatric procedures nowadays are employed under ERAS protocol as an ambulatory surgery. Pain after laparoscopic procedures arises significantly from port site incisions in the anterior abdominal wall, and shoulder…
- Conditions
- Bariatric Surgery Candidate, Pain, Postoperative, Narcotic Use, Analgesia
- Trial name
- NCT05592522
- Testing
- External oblique intercostal block, Oblique subcostal TAP block, Posterior Rectus sheath block
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
Heart Disease
Effect of GLP-1 on Postprandial Lipid Metabolism
Individuals with obesity have an increased risk for heart disease and diabetes. There are current drugs on the market that target the hormone, Glucagon like peptide-1 (GLP-1) to treat diabetes.
- Trial name
- NCT01760772
- Testing
- Exendin-9, GLP-1, saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- David Dalessio
Obesity
Effects of Alcohol After Bariatric Surgery
The investigators wish to study the effects of three forms of bariatric surgery: gastric bypass, sleeve gastrectomy, and lap banding. The surgery is not part of the clinical trial.
- Trial name
- RBA (NCT01843257)
- Testing
- Alcohol challenge test Alcohol visit first
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge.
- Conditions
- Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
- Trial name
- NCT04644445
- Testing
- Bariatric Full Liquid Diet
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Type 2 Diabetes Mellitus
The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass
The study is being undertaken to understand how the Roux-en-Y Gastric Bypass procedure can affect insulin secretion after meals.
- Trial name
- NCT01843881
- Testing
- Exendin 9, 39
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adrian Vella
Type 2 Diabetes, Obesity
Changes in Incretins Response and Glycemic Control After Gastric Bypass Surgery in Type 2 Diabetic Patients Versus Healthy
The purpose of this study is to determine the early changes in gut hormonal, and other metabolites with known relations to the glycemic homeostasis.
- Trial name
- NCT01820273
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Roux-en-y Gastric Bypass, Post Prandial Hypoglycemia
Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.
The primary objective of this study is to assess the neuro-endocrine response to hypoglycaemia in PHH vs. non-PHH post-gastric bypass individuals.
- Trial name
- DEEP1B (NCT04334161)
- Testing
- Administration of glucose and controlled induction of hypoglycaemia.
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lia Bally