Clinical trials: Post-Operative Anemia
Gynecologic Cancer, Anemia
Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)
Iron deficiency has been reported in approximately 35% of patients with a gynecologic malignancy. Blood transfusions are known to be immunosuppressive and carry immediate and long-term risks.
- Conditions
- Gynecologic Cancer, Anemia, Iron-deficiency
- Trial name
- FORGE II (NCT05407987)
- Testing
- Ferric derisomaltose
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- AHS Cancer Control Alberta
Anaemia Postoperative
Clinical Utility of Postoperative Hemoglobin Testing
The purpose of this study is to evaluate how many patients have hemoglobin less than 10 g/dL at post-operative day 1
- Trial name
- NCT04170764
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- TriHealth Inc.
IDA in the Post-bariatric Surgical Patient
Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient
The aim of the study is to compare two accepted treatments for iron deficiency anemia (oral ferrous sulfate and intravenous ferumoxytol) for efficacy and speed of response in the treatment of iron deficiency anemia (IDA) in the…
- Trial name
- NCT03777514
- Testing
- Ferumoxytol, Ferrous sulfate, Oral vitamin C
- Sponsor
- Johns Hopkins University
Surgical Blood Loss, Transfusion-dependent Anemia
Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery
The goal of this clinical trial is to learn if the administration of tranexamic acid can reduce the necessity of blood transfusions in adult patients undergoing major abdominal surgery. .
- Conditions
- Surgical Blood Loss, Transfusion-dependent Anemia, Abdomen Disease
- Trial name
- TATRA (NCT06414031)
- Testing
- Tranexamic Acid
- Where
- 2 sites in Germany
- Volunteers
- 892 people
- Sponsor
- Ulrich Ronellenfitsch, MD
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate
Tranexamic Acid for Bleeding Reduction During TURP Surgery
Transurethral resection of the prostate (TURP) is commonly performed in elderly patients and may be associated with perioperative bleeding leading to postoperative anemia and delayed recovery.
- Conditions
- Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate, Perioperative Bleeding, Anemia, Postoperative
- Trial name
- TXA-TURP (NCT07460518)
- Testing
- Tranexamic Acid
- Where
- Morocco
- Volunteers
- 80 people
- Sponsor
- Hamza Najout
Blood Loss Anemia
Postoperative Replacement of Intraoperative Iron Losses
By performing a randomized, blinded placebo controlled exploratory trial we speculate that replacement of perioperative, bleeding-induced iron losses with ferric carboxymaltose immediately after the surgical procedure can…
- Trial name
- POREIIL (NCT03680456)
- Testing
- Ferric carboxymaltose, Crystalloid
- Where
- Austria
- Volunteers
- 134 people
- Sponsor
- Kepler University Hospital
Perioperative Anemia, Surgery
The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery
The prognosis of patients undergoing spinal deformity surgery is often compromised by perioperative anemia due to iron deficiency.
- Conditions
- Perioperative Anemia, Surgery, Spinal Deformity, Adult
- Trial name
- NCT05714007
- Testing
- Ferric derisomaltose, Ferrous succinate
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Pancreaticojuodenectomy
The Role of Intravenous Ferritin in Optimizing Postoperative Recovery Following Pancreaticoduodenectomy
Iron deficiency anemia is well known as a risk factor that worsens postoperative morbidity and patient prognosis. Several studies have shown that intravenous iron administration before surgery is effective in reducing the risk of…
- Trial name
- Ferritin (NCT06442111)
- Testing
- The intravenous ferritin group
- Volunteers
- 106 people
- Sponsor
- Seoul St. Mary's Hospital
Anemia
Pilot Study of Epoetin Alfa for Patients Having Abdominal or Pelvic Surgery for Cancer
This pilot study is looking at how well epoetin alfa, given in the immediate post-operative period, works in reducing anemia and the need for transfusions.
- Trial name
- NCT00294203
- Testing
- Epoetin Alfa group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Colon Cancer
Preoperative i.v. Iron Substitution in Patients With Colon Cancer
About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival.
- Trial name
- PREFECO (NCT04653181)
- Testing
- Ferric carboxymaltose
- Where
- Finland
- Volunteers
- 514 people
- Sponsor
- Helsinki University Central Hospital
Cerebral Aneurysm Unruptured, Iron Deficiency Anemia
Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery
Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.
- Conditions
- Cerebral Aneurysm Unruptured, Iron Deficiency Anemia, Surgery
- Trial name
- PICASA (NCT04616092)
- Testing
- FEFINJECT
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Anemia, Cardiac Surgery
Mediation Analysis in Cardiac Surgery
This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery.
- Conditions
- Anemia, Cardiac Surgery, Transfusion, Mediation
- Trial name
- MACS (NCT07092683)
- Testing
- anemia, nonanemia
- Where
- China
- Volunteers
- 13,683 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Anemia, Knee Osteoarthritis
Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561506
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Postoperative Anemia, Knee Osteoarthritis
Effect of Postoperative Ferric Carboxymaltose
The primary purpose of this study is to evaluate the safety and efficacy of postoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561480
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Colorectal Neoplasm, Anemia
Intravenous Iron: Measuring Response in Anemic Surgical Patients
20 Patients will be recruited with confirmed colorectal adenocarcinoma and anemia who are planned to undergo surgery. All patients will be treated with a single dose of 1g intravenous ferric carboxymaltose (FERINJECT).
- Trial name
- NCT02057471
- Testing
- Intravenous ferric carboxymaltose
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Anemia, Bariatric Surgery Candidate
Postoperative Anemia After Bariatric Surgery
To investigate the real incidence of short and long-term anemia after bariatric surgery, and explore the risk factors.
- Trial name
- NCT06198790
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China-Japan Friendship Hospital
Anemia, Iron Deficiencies
Postoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery
Postoperative anemia is highly prevalent among patients undergoing cardiac surgery and is associated with delayed functional recovery, increased morbidity, and impaired long-term outcomes.
- Conditions
- Anemia, Iron Deficiencies, Iron Deficiency Anemia, Cardiac Surgery
- Trial name
- NCT07238972
- Testing
- Ferric derisomaltose
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
Postoperative Anemia, Arthroplasty, Replacement, Hip
Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia
To assess the safety, tolerability, efficacy, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of orally administered SSS17 capsules in patients with postoperative anemia following elective total hip or knee…
- Conditions
- Postoperative Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT07007936
- Testing
- SSS17 Capsule (6 Dose Levels)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Anemia, Intensive Care
Observational Study of Iron Metabolism in Anemia in ICU and Post-Operative Patients
Anemia in intensive care and post-operative patients is due to both blood loss (leading to iron loss) and inflammation.
- Conditions
- Anemia, Intensive Care, Cardiac Surgery
- Trial name
- FAIRe (NCT00338234)
- Where
- France
- Volunteers
- 153 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Resection, Anemia
Preoperative Anemia Affected to Postoperative Outcomes in Liver Resection
To assess the impact of preoperative anemia on postoperative outcomes in patients undergoing liver resection
- Conditions
- Liver Resection, Anemia, Postoperative Mortality and Morbidity
- Trial name
- NCT06905041
- Volunteers
- 728 people
- Sponsor
- Chiang Mai University