Clinical trials: Post-Operative Adhesions
Retained Products of Conception, Intrauterine Adhesion
Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss
Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications.
- Trial name
- NCT04637373
- Testing
- Hysteroscopy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Primary Graft Dysfunction
Quantifying Physical and Biochemical Factors That Contribute to Primary Graft Dysfunction After Lung Transplantation
Primary graft dysfunction (PGD or lung reperfusion edema) complicates 10 to 20% of lung transplantations and leads to severe early and late postoperative complications.
- Trial name
- NCT01151826
- Where
- 4 sites in France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Strasbourg, France
Benign Gynecological Disease, Uterine Fibroids
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery
This prospective observational registry aims to systematically collect preoperative, intraoperative, and postoperative clinical data from patients undergoing surgery for benign gynecological conditions.
- Conditions
- Benign Gynecological Disease, Uterine Fibroids, Endometriosis, Adenomyosis
- Trial name
- OPGYNBEN (NCT07772076)
- Testing
- Standard Surgical Procedures for Benign Gynecological Conditions
- Where
- Italy
- Volunteers
- 6,000 people
- Sponsor
- IRCCS San Raffaele
Pelvic Floor Muscle Electrophysiologic Therapy, Fast-Track Surgery
Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery
This study is to evaluate the effect of pelvic floor muscle electrophysiologic therapy on enhanced recovery after gynecologic surgery,to solve muscle soreness and retention of urine after laparoscopy, and endometrial repair after…
- Trial name
- NCT03524807
- Testing
- Electrophysiologic therapy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Infertility, Abortion, Spontaneous
Development of a Bioabsorbable Medical Device for the Prevention of Postoperative Intra-uterine Adhesions.
The main objective of this study is to describe the level of expression of the biological factors involved in the formation of adhesions (Transforming growth factor beta, Activin A, inhibin) at the time of a first diagnostic…
- Conditions
- Infertility, Abortion, Spontaneous, Embryo Implantation, Delayed
- Trial name
- PréSynUT-1 (NCT02328742)
- Testing
- Hysteroscopy + endometrial biopsy, Telephone call, Resection + endometrial biopsy
- Where
- 3 sites in France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Uterine Septum
Intrauterine Balloon and Postoperative Estrogen Therapy in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis
Patients who want to go TCRS will randomly divided 3 groups. In Group 1(100 patients), women received postoperative estrogen therapy.
- Trial name
- NCT02617108
- Testing
- Foley balloon
- Volunteers
- 310 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Acute Cholecystitis With Chronic Cholecystitis
Correlation Between Power Doppler and Intraoperative Findings of Chronic and Acute Cholecystitis
In theory, increased vascularity of GB wall could be associated with intraoperative findings, such as, GB wall inflammation and accompanying adhesions.
- Trial name
- NCT02156947
- Testing
- Laparoscopic cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun Education and Research Hospital
Intrauterine Adhesions, Chronic Endometritis
Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions
This study is to evaluate the prevalence of chronic endometritis (CE) in women with severe intrauterine adhesions and compare recurrence of adhesion in women with and without CE.
- Trial name
- NCT02744807
- Testing
- Chronic endometritis
- Volunteers
- 125 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Intrauterine Adhesion
Efficacy of Estrogen-intrauterine Stent System After Intrauterine Adhesiolysis
This is a prospective, randomized, single-blinded,multi-center trial to compare the efficacy of an Estrogen-intrauterine stent system with foley balloon combined with intrauterine cross-linked sodium hyaluronate gel in the…
- Trial name
- NCT04972032
- Testing
- Estrogen Intrauterine Stent System, Foley balloon combined with self-cross-link sodium hyaluronate gel
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Limin Feng
Skin (FLACC Scores of Test Subjects) After Tape Removal
Assessment of Wound Care Product Skin Adhesion
The purpose of this exploratory study is to assess the adhesive forces to skin of samples over the period of 24 hours to establish the peel-off measurement method at the Essity study site.
- Trial name
- SWAP (NCT07136870)
- Testing
- Medical tape
- Where
- Sweden
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Intrauterine Adhesion
Postoperative Intermittent Intrauterine Balloon Dilatation Therapy.
In this prospective, randomized, controlled study, the investigators wish to determine the efficacy of intrauterine balloon (IUB) dilatation in the prevention of adhesion reformation when compared with the conventional management.
- Trial name
- NCT03131596
- Testing
- IUB dilatation therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel
Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions
Women undergoing operative hysteroscopy for removal of retained placenta after delivery will be randomized into two groups. 1. study group - immediately after operative hysteroscopy 5 ml hyaluronic acid gel will be injected into…
- Trial name
- NCT04975373
- Testing
- Intrauterine injection of hyaluronic acid
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Barzilai Medical Center
Thyroidectomy
Use of an Oxidized Regenerated Cellulose After Thyroid Surgery: A Prospective, Randomized Study
The purpose of this study is to evaluate the effects and safety of oxidized, regenerated cellulose as an absorbable adhesion barrier after thyroidectomy.
- Trial name
- ORC (NCT01171079)
- Testing
- application of oxidized regenerated cellulose
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Myoma
Intrauterine Adhesion Rate After Hysteroscopic Myomectomy and Application of HYALOBARRIER Gel
The purpose of this study is to evaluate the intrauterine adhesion rate after the application of HYALOBARRIER Gel at the end of hysteroscopic myomectomy. Secondary endpoints were tolerance and side effect and subsequent fertility.
- Trial name
- HYGEM (NCT01412489)
- Testing
- HYALOBARRIER Gel
- Where
- France
- Volunteers
- 189 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ulcerative Colitis, Familial Polyposis
An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery
This will be a prospective, multi-center, randomized, single blind study to collect and evaluate post-market clinical data on the SprayShield Adhesion Barrier System as an adjuvant to good surgical technique for the reduction of…
- Trial name
- NCT01002287
- Testing
- SprayShield Adhesion Barrier System, Good Surgical Technique Alone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Integra LifeSciences Corporation
Postoperative Adhesion of Uterus
Pivotal Clinical Study to Assess the Anti-adhesive Effect and Safety of ABT13107 Applied to Postoperative Intrauterine
This study is intended to evaluate the efficacy and safety of ABT13107 compared to Hyalobarrier applied to postoperative intrauterine.
- Trial name
- NCT04007211
- Testing
- ABT13107, Hyalobarrier
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Medy-Tox
Prostate Cancer, Postoperative Adhesion
The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery
To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic pelvic surgery (radical prostatectomy).
- Trial name
- NCT02773251
- Testing
- hyaluronic acid-carboxymethylcellulose
- Volunteers
- 60 people
- Sponsor
- Bucheon St. Mary's Hospital
Thumb Joint Stiffness
Electrical Stimulation to Recover Greater Range of Motion After Surgery
Background One of the potentially debilitative complications of operative repair and subsequent immobilization is stiffness that appears secondary to inflammation and adhesions.
- Trial name
- NCT01082432
- Testing
- electrically induced muscle activation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Joseph Fourier
Asherman Syndrome, Intrauterine Adhesion
Evaluate Formation of IUAs After Third-generation Endometrial Ablation, With and Without Intrauterine Adhesion Barrier
Evaluate the formation of adhesions after third-generation endometrial ablation, with and without the intrauterine adhesion barrier.
- Trial name
- CLEAN (NCT05414760)
- Testing
- Womed Leaf
- Where
- 2 sites in Netherlands
- Volunteers
- 1 people
- Sponsor
- Remko P. Bosgraaf