Clinical trials: Post Traumatic Stress Disorders
Post-Traumatic Stress Disorder
Assessing PTSD After Earthquake in Turkey
Assessing the prevalence and natural course of PTSD after the 1999 Turkish earthquake
- Trial name
- NCT00269451
- Sponsor
- Sheba Medical Center
PTSD, Anger
Breaking the Cycle IV: Military PTSD (MPTSD) Treatment Study
The study will compare the efficacy of Trauma Affect Regulation: Guide for Education and Therapy (TARGET) vs. the best validated psychotherapy for adults with posttraumatic stress disorder (PTSD), Prolonged Exposure (PE).
- Conditions
- PTSD, Anger, Aggression
- Trial name
- MPTSD (NCT01228539)
- Testing
- TARGET (Trauma Affect Regulation), Prolonged Exposure
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- UConn Health
Lung Cancer, Prostate Cancer
Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia
Patients who receive radiation therapy often have fatigue or a decrease in feeling well causing a "wasting" away. For patients with advanced disease of lung cancer, prostate cancer, or cancer that has spread to the bone, it is…
- Conditions
- Lung Cancer, Prostate Cancer, Neoplasm Metastasis, Bone Cancer
- Trial name
- NCT00127387
- Testing
- Enbrel
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Domestic Violence, Psychological Distress
GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda
The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience \& Understanding Self-help Therapy' (TRUST) in managing domestic violence \& primary trauma among formerly…
- Conditions
- Domestic Violence, Psychological Distress, Post-Traumatic Stress Disorder, Suicidality
- Trial name
- GBV (NCT06073964)
- Testing
- Trauma Resilience & Understanding Self-help Therapy
- Where
- Uganda
- Volunteers
- 284 people
- Sponsor
- Kampala International University
PTSD
Can Exercise Improve Therapeutic Learning Among Women With Posttraumatic Stress Disorder
This study aims to test whether aerobic exercise improves the consolidation and subsequent recall of the learned safety memories among adult women with PTSD related to interpersonal violence exposure and whether this effect is…
- Trial name
- PTSD (NCT04417309)
- Testing
- Experimental, Active Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Adams
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
PTSD, Trauma, Psychological
Narrative Exposure Therapy for Adults With Intellectual Disability
The purpose of the study is to identify how Narrative Exposure Therapy (NET) can be adapted for delivery with adults with mild Intellectual Disability (ID) and to explore whether NET can reduce symptoms of traumatic stress in…
- Trial name
- NCT04418752
- Testing
- Psychological therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nottingham
Stress Disorders, Post-Traumatic, Smoking
CPT and Smoking Cessation
Posttraumatic stress disorder (PTSD) and cigarette smoking are both associated with significant impairment in Veterans and cost to the Veterans' Affairs (VA) system.
- Trial name
- NCT01901848
- Testing
- Cognitive Processing Therapy (CPT), Bupropion, nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
PTSD
Impact of Supported Employment Versus Standard Vocational Rehabilitation in Veterans With Post-traumatic Stress Disorder
This prospective randomized study evaluates the impact of Supportive Employment (SE) compared to standard vocational rehabilitation (VRP) on occupational, sobriety, psychiatric, and quality of life outcomes and health care costs…
- Trial name
- NCT00728325
- Testing
- Supported Employment (SE), Standard Vocational Rehabilitation (VRP)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Trauma
Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders
The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery.
- Trial name
- IRTIPAP (NCT06432400)
- Testing
- Patient questionnaires
- Where
- 2 sites in France
- Sponsor
- Hôpital NOVO
Stress Disorders, Post-Traumatic
Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial
This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD).
- Trial name
- CARE4PTSD (NCT05244564)
- Testing
- Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Uniformed Services University of the Health Sciences
Post-traumatic Stress Disorder, Stress Disorder, Post-Traumatic
Trial of Art Therapy During Cognitive Processing Therapy for PTSD
This is a randomized, controlled trial of adjunctive art therapy during cognitive processing therapy for PTSD.
- Trial name
- Art_Tx_PTSD (NCT02610049)
- Testing
- Cognitive Processing therapy, Art + CPT, CPT + Art Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Hampton VA Medical Center
PTSD
Pilot Trial of Mobile Mantram Delivery
Mantram Repetition Program (MRP) is a meditation practice that involves silent repetition of a spiritual word, one-pointed attention, and slowing down. It has been shown to help reduce PTSD symptoms among Veterans.
- Trial name
- mMRP (NCT05998967)
- Testing
- Mobile Mantram Repetition Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
PTSD
Concentrated Exposure Therapy for Post-traumatic Stress Disorder - a Cohort Study
Post-traumatic stress disorder (PTSD) is a prevalent and disabling condition. Trauma-focused psychotherapy, including cognitive behavioural therapy (CBT), are among the recommended first-line treatment alternatives.
- Trial name
- NCT05598099
- Testing
- Concentrated cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 42 people
- Sponsor
- Haukeland University Hospital
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Post-Traumatic Stress Disorders, Stress Disorders
Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings
The purpose of this study is to evaluate Cognitive-behavioral therapy (CBT) for deployment-related post-traumatic stress disorder (PTSD) that can be used by behavioral health consultants working with Service Members in the…
- Conditions
- Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
- Trial name
- NCT00974402
- Testing
- Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders
Background Anxiety disorders are the most prevalent psychiatric disorders around the world. Effective treatment consists of pharmacotherapy or psychological treatment based on cognitive-behavioral therapy (CBT) and these…
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT06937892
- Testing
- Transdiagnostic metacognitive therapy, Disorder-specific cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Karolinska Institutet
Depression, Anxiety
REstoring Mental Health Through COmmUnity-based Psychological Services in New York City
The goal is to improve mental health. The study will evaluate the impact of community-based mental health services. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan…
- Conditions
- Depression, Anxiety, Psychological Distress, PTSD
- Trial name
- RECOUP-NY (NCT04913766)
- Testing
- Problem Management Plus, Services as Usual
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- George Washington University
Agitated; State, Acute Reaction to Stress
Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation
The aim of the study is to identify the role of preoperative chlorepheniramine maleate on alleviating or reducing the severity of postoperative agitation following FESS procedures.
- Trial name
- NCT04293081
- Testing
- Preemptive chlorepheniramine maleate intravenous injection, normal saline
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post Traumatic Stress Disorder, Depression
Brief Peer Supported webSTAIR Compared to Enhanced Wait List
This study will enroll 180 Veterans at a 2:1 ratio where 120 Veterans will be enrolled into a brief transdiagnostic peer supported webSTAIR (BPS webSTAIR) and 60 will be supported into Waitlist.
- Conditions
- Post Traumatic Stress Disorder, Depression, Emotion Regulation
- Trial name
- BPSwS (NCT04286165)
- Testing
- Brief Peer Supported webSTAIR
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Palo Alto Veterans Institute for Research
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