Clinical trials: Post Traumatic Stress Disorder PTSD, open to volunteers
Posttraumatic Stress Disorder (PTSD)
Resilience Building Among Older Adults: the Heart Math Based Interventions for Posttraumatic Stress Disorder, Spirituality and Psychosocial Well-being
Resilience building among older adults: The Heart Math based interventions for posttraumatic stress disorder, spirituality and psychosocial well-being.
- Trial name
- Resilience (NCT06746818)
- Testing
- Heart Math interventions
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
PTSD
Exercise and Emotional Learning in Posttraumatic Stress Disorder
The goal of this clinical trial is to test how exercise affects learning and memory processes relevant to the treatment of PTSD. Participants will complete a baseline intake followed by two experimental sessions.
- Trial name
- NCT06127342
- Testing
- Moderate Intensity Exercise, Low Intensity Exercise
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Christal L Badour
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Stress, Trauma
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their…
- Conditions
- Stress, Trauma, PTSD, HPA
- Trial name
- NCT06311188
- Testing
- ITR Healing intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults.
Post-traumatic stress disorder (PTSD) is a mental health condition that's triggered by the experience of potentially traumatic events.
- Trial name
- NCT06516874
- Testing
- Trauma-Focused Cognitive Behavioral Therapy for complex presentation (TF-CBT-CP)
- Where
- 5 sites in Chile
- Volunteers
- 13 people
- Sponsor
- University of Talca
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Neuromodulation and Neurorehabilitation for mTBI
This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing training (APT) when combined with intermittent theta burst stimulation…
- Trial name
- NCT03819608
- Testing
- real iTBS, real APT
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Posttraumatic Stress Disorder
Prolonged Exposure for Swedish Immigrants
The goal of this clinical trial is to compare therapist-guided internet delivered prolonged exposure (I-PE) in simple english to a waiting list condition for immigrants in Sweden diagnosed with post-traumatic stress disorder…
- Trial name
- NCT06193161
- Testing
- Therapist-supported internet delivered prolonged exposure
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
PTSD, Post Traumatic Stress Disorder
Improving Therapeutic Learning for PTSD
The proposed project seeks to demonstrate the engagement of post-exposure dopamine neurotransmission and downstream acute reorganization of dopaminergic resting-state neural networks as a means of increasing consolidation of…
- Trial name
- NCT04558112
- Testing
- L-DOPA
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
PTSD, Emotion Regulation Disorders
Hybrid Dialectical Behavior Therapy for Veterans to Further Reduce Emotion Regulation Problems and Trauma Symptoms
Around 10% of post-active veterans experience post-traumatic stress disorder (PTSD) many years post-mission. PTSD in veterans is frequently associated with challenges in emotion regulation, aggression, suicidality, and financial…
- Conditions
- PTSD, Emotion Regulation Disorders, Substance Abuse
- Trial name
- REFRESH (NCT07652645)
- Testing
- Hybrid dialectical behavior therapy
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Arkin
Depression Disorder, Post Traumatic Stress Disorder PTSD
The Effects of Extreme Prematurity on Parenting
In France, perinatal mental health has become a major public health issue. Maternal mental health conditions can have serious consequences, including death by suicide.
- Trial name
- PREMA-PSY (NCT07918365)
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
PTSD - Post Traumatic Stress Disorder
Written Exposure Therapy Plus Adjunctive Methylphenidate Treatment for Veterans With PTSD
Many Veterans with post-traumatic stress disorder (PTSD) do not fully benefit from the best current treatments, some of which focus on helping the brain regulate trauma memories.
- Trial name
- WET+MPH (NCT07904000)
- Testing
- Written Exposure Therapy (WET), methylphenidate (MPH)
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- VA Office of Research and Development
PTSD - Post Traumatic Stress Disorder, Depression
Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals
This study will examine the effects of Eye Movement Desensitization and Reprocessing (EMDR) group therapy on adults who experienced the April 2025 Silivri earthquake in Turkey.
- Conditions
- PTSD - Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Sleep Quality
- Trial name
- NCT07206381
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Group Therapy
- Volunteers
- 40 people
- Sponsor
- Istanbul Galata University
Anxiety, PTSD
Temporal Interference in Psychiatry (TIP): Neuromodulation Using Temporal Interference
This study aims to understand the neural, behavioral and clinical effects of temporal interference (TI), a type of neuromodulation method, in healthy populations and in individuals with anxiety and stress-related conditions.
- Trial name
- NCT07558759
- Testing
- Electrical stimulation device
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Complex Post-Traumatic Stress Disorder
Treatment of Complex Post-traumatic Stress Disorder Among Displaced People in Switzerland and Germany
In WHO ICD-11 (its latest edition), the diagnostic criteria for post-traumatic stress disorder (PTSD) were revised, and a new sibling disorder, complex post-traumatic stress disorder (CPTSD) was introduced.
- Trial name
- ESTAIR_REFUGEE (NCT07015567)
- Testing
- Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET), Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET), Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)
- Where
- 8 sites in Germany, Switzerland
- Volunteers
- 288 people
- Sponsor
- Eva Heim
PTSD - Post Traumatic Stress Disorder
Evaluating Evidenced Based Options for PTSD Treatment
This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment.
- Trial name
- NCT06733376
- Testing
- Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
Posttraumatic Stress Disorder (PTSD), Depression - Major Depressive Disorder
To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder
This study aims to investigate the immediate neurophysiological and autonomic effects of two noninvasive brain stimulation protocols-prolonged intermittent theta-burst stimulation (prolonged iTBS) and high-frequency repetitive…
- Trial name
- NCT07327385
- Testing
- Prolonged Intermittent Theta-Burst Stimulation (prolonged iTBS), High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Posttraumatic Stress Disorder, Depression
Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury
The purpose of this study to learn about patients' experience with the Trauma Resilience and Recovery program (TRRP) and/or the enhanced care group.
- Trial name
- NCT05497115
- Testing
- Trauma Resilience and Recovery Program
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder (PTSD)
Psilocybin-Assisted Psychotherapy for Veterans With PTSD
This study will evaluate the feasibility, safety and preliminary efficacy of psilocybin-assisted psychotherapy in military veterans with treatment-refractory posttraumatic stress disorder (PTSD).
- Trial name
- PsiVet (NCT07792538)
- Testing
- Psilocybin-assisted Psychotherapy
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- ARQ National Psychotrauma Centre
PTSD - Post Traumatic Stress Disorder, PTSD (Childbirth-Related)
The New Empowerment After eXposure to Trauma (NEXT) Study
The NEXT Study is a randomized controlled pilot examining the feasibility and acceptability of a revised perinatal PTSD protocol.
- Trial name
- NEXT (NCT07175025)
- Testing
- Narrative Exposure Therapy (NET)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University