Clinical trials: Post Stroke Depression
Depression, Stroke
Feasibility of the Post-Stroke Depression-toolkit
Rationale: Depression is a frequent complication after a stroke. In stroke guidelines several recommendations focus on early screening, and treatment off depression after stroke.
- Trial name
- NCT03500250
- Testing
- Post-Stroke Depression toolkit
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Utrecht
Stroke, Post-stroke Depression
The Research Team Aims to Elucidate the Impact of ITBS (intermittent Theta Burst Stimulation) on the HPA Axis and Post-stroke Negative Emotions/depression by Conducting Human Experiments That Target Various Brain Regions.
The project team will categorize stroke patients into three groups receiving iTBS stimulation targeting distinct brain regions: the cerebellum, the dorsolateral prefrontal cortex (DLPFC), and the primary motor cortex (M1), with…
- Trial name
- NCT06899893
- Testing
- iTBS
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stroke, Stress, Psychological
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of an psychotherapeutic frame…
- Conditions
- Stroke, Stress, Psychological, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06633146
- Testing
- Therapies in nature
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Cerebral Stroke
Links Between Depression, Anxiety, Coping and Quality of Life After a Stroke
Introduction and literature review With 130 000 cases per year in France in 2010, stroke is one of the most common neurological diseases, often leaving many disabling sequelae physical and cognitive levels (currently live 500 000…
- Trial name
- COPING (NCT02778334)
- Testing
- survey
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Post-stroke Depression
Investigating How the RECT Impacts Brain Functional States Through the ACC-cerebellar Loop
Experiment1: Using a brain EEG-TMS combined system, researchers aim to investigate the impact of the rostral anterior cingulate cortexr (rACC)-engaging cognitive task (RECT) combined single-pulse TMS magnetic stimulation on theta…
- Trial name
- NCT06912191
- Testing
- Left cerebellar TMS stimulation combined with the RECT task, Right cerebellar TMS stimulation combined with the RECT task, Midline cerebellar TMS stimulation combined with the RECT task
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Depression, Old Age; Debility
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Depression is common among elderly patients hospitalized due to acute conditions like strokes or osteoporotic fractures. It has significant impacts on quality of life, hospitalization rates, and mortality.
- Conditions
- Depression, Old Age; Debility, Stroke, Fractures, Bone
- Trial name
- NCT06570356
- Testing
- Geriatric Depression Scale - 15
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Stroke, Depressive Symptoms
Instant Message-delivered Brief Internet-based Cognitive Behavioural Therapy (iCBT) for Post-stroke Depression
Around one third of stroke survivors develop depression at any point of time following the stroke event. Post-stroke depression (PSD) is associated with negative care outcomes including poorer function, longer hospital stays…
- Conditions
- Stroke, Depressive Symptoms, Mobile Phone Use
- Trial name
- NCT05892965
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Post-stroke Depression
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
Experiment 1: Utilizing a transcranial magnetic stimulation-electroencephalography/functional near-infrared spectroscopy system, the investigators aim to determine whether transcranial magnetic stimulation of the cerebellum can…
- Trial name
- NCT06860451
- Testing
- TMS
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Post-stroke Depression
rTMS as an add-on Therapy in Patients With Post-stroke Depression
About 50% of all stroke patients develop post-stroke depression (PSD). A meta-analysis has shown that rTMS treatment can reduce depressive symptoms in PSD patients.
- Trial name
- NCT03761303
- Testing
- active rTMS
- Where
- Germany
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Stroke, Post-stroke Depression
Effects of Robotic Rehabilitation on Quality of Life, Mood, and Fatigue After Stroke
Stroke is a major cause of long-term disability and is often associated with reduced quality of life, depression, anxiety, and fatigue.
- Conditions
- Stroke, Post-stroke Depression, Post-stroke Anxiety, Post-stroke Fatigue
- Trial name
- NCT07203937
- Testing
- RoboGait® Robotic Gait Training, Treadmill Walking Training
- Volunteers
- 36 people
- Sponsor
- Meltem Gunes Akinci
Stroke, Depression
Mobile Technologies and Post-stroke Depression
The recent development of acute phase treatments has dramatically improved stroke functional outcome but post-stroke neuropsychiatric disorders, notably post-stroke depression, continue to contribute to the heavy burden of…
- Trial name
- MOTIV-POSDEP (NCT04043052)
- Testing
- Psychological evaluation, Functional evaluation, Biological assessment
- Where
- 5 sites in France
- Volunteers
- 401 people
- Sponsor
- University Hospital, Bordeaux
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Post-stroke Depression
Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation on Patients With Post-stroke Depression
The FDA approved repetitive transcranial magnetic stimulation (rTMS) for patients with Major Depressive Disorder (MDD) in 2008. The conventional rTMS protocol that has been used effectively for major depression is 5 days per week…
- Trial name
- NCT06157333
- Testing
- The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Post-stroke Depression
Affective Touching on Poststroke Depression
This mixed-method study includes a randomised controlled trial and an exploratory qualitative study, and aims to examine the effects of caregiver-delivered affective touch on depressive symptoms, state of attachment security…
- Trial name
- NCT03789994
- Testing
- Affective touch, Fine motor exercise
- Where
- China
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Post-stroke Depression
ATtention Test and Executive Functions After STroke to Predict Depression.
The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.
- Trial name
- ATTEST-Depress (NCT04008719)
- Testing
- Thymic history, Evaluation of the psychiatric disorders, Cognitive evaluation
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier St Anne
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Stroke, Depression
MEditation for Post Stroke Depression
The purpose of this study is to establish the feasibility and acceptability of a breath-based meditation in stroke survivors with post-stroke depression (PSD) and their informal caregivers, as well as to examine the effects of…
- Trial name
- MEND (NCT03239132)
- Testing
- Breath-based meditation, Meditation educational materials
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ischemic Stroke, Acute
A Multicenter Study Based on Multi-omics Analysis to Predict the Early Prognosis and Recurrence Risk of Acute Ischemic Stroke
Through a multicenter prospective AIS cohort study, we analyze the potential association of human proteome, microbiome and metabolome alterations with AIS prognosis, searching for key proteins, differential organisms and…
- Trial name
- NCT06584565
- Testing
- microbiome; metabolomics; proteomics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Cerebral Apoplexy, Depression Anxiety Disorder
Efficacy and Safety Evaluation of Remote Ischemic Adaptation ( Intermittent Pressure Stimulation ) in the Treatment of Insomnia After Stroke
The incidence of post-stroke depression is high, which will affect the rehabilitation of neurological function, damage cognitive function, and increase the risk of subsequent stroke recurrence.
- Conditions
- Cerebral Apoplexy, Depression Anxiety Disorder, Cerebrovascular Disease
- Trial name
- NCT07401784
- Testing
- Automatic ischemic preconditioning therapeutic apparatus
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Nanchang University