Clinical trials: Post Operative Pain After Root Canal Therapy
Root Canal Treatment, Post Operative Pain
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
The study design is a single-center 2-arm randomized controlled clinical trial. 10 subjects (teeth) requiring a root canal treatment will be enrolled in 2 groups (5 in each group).
- Trial name
- NCT05374434
- Testing
- Conventional irrigation, Inertial cavitation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Root Canal Therapy
Postoperative Pain Assessment After Using Different Kinematics
The aim of this study is to evaluate postoperative pain after endodontic instrumentation using rotation, reciprocation and adaptive motion.
- Trial name
- NCT04277520
- Testing
- Root canal therapy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Post Operative Pain, Acute
Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment.
- Trial name
- NaOCl-RCT (NCT07618182)
- Testing
- Sodium Hypochlorite Irrigation
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Symptomatic Irreversible Pulpitis (SIP)
Hypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar.
This randomized controlled trial evaluates whether a final flush with 3% hypertonic saline, compared with 0.9% normal saline, reduces post-operative pain and periapical Substance P (SP) levels after single-visit root canal…
- Trial name
- Hypertonic (NCT07701551)
- Testing
- Normal (0.9%) saline, Hypertonic 3% saline
- Volunteers
- 40 people
- Sponsor
- Cairo University
Symptomatic Apical Periodontitis, Postoperative Pain
Photobiomodulation After Nonsurgical Root Canal Treatment
This randomized, double-blind controlled clinical trial will evaluate whether adjunctive photobiomodulation improves recovery after nonsurgical root canal treatment in adults with teeth diagnosed with symptomatic apical…
- Conditions
- Symptomatic Apical Periodontitis, Postoperative Pain, Mechanical Allodynia
- Trial name
- NCT07886723
- Testing
- Adjunctive Photobiomodulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Periapical Diseases
Evaluation of Post Operative Pain After Using Intracranial Cryotherapy During Single Visit RCT
A total of 60 patients presenting with single-rooted teeth exhibiting symptomatic apical periodontitis were subjected to a randomized allocation into two groups of 30 each.
- Trial name
- NCT07598188
- Testing
- Saline 0.9% (1.5-2.5°C)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Symptomatic Irreversible Pulpitis
Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: A RCT
Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis.
- Trial name
- NCT05681494
- Testing
- Root canal treatment, Vital pulp therapy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Postoperative Pain After the Use of Different Last Irrigation Method During Root Canal Treatment in Primary Teeth
This study was to evaluate and compare the postoperative pain levels after using EndoActivator and conventional endodontic syringe irrigation in root canal therapy of primary molars.
- Trial name
- NCT04197531
- Testing
- Irrigation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Post Operative Pain, Root Canal Therapy
Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment
Fifty-eight patients aged 18-60 years, diagnosed with symptomatic or asymptomatic apical periodontitis will be randomly allocated into two groups: Group A (EndoActivator) and Group B (conventional syringe irrigation).
- Trial name
- NCT07062419
- Testing
- endoactivator
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Pulpal Inflammation
Assessment of Pain Using Two Different Irrigation Systems After Root Canal Treatment
assessment of pain using two different irrigation systems after root canal treatment
- Trial name
- NCT07108842
- Testing
- Conventional Needle Irrigation, Conventional Needle Irrigation (Control Group), endoactivator
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- HITEC-Institute of Medical Sciences
Symptomatic Apical Periodontitis
Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis
Clinical Evaluation of the Postoperative Pain and Substance P levels Following the use of Bioceramic verses Calcium Hydroxide Intracanal Medicaments in Permanent Mandibular molars with Symptomatic Apical Periodontitis
- Trial name
- (BCvsCaOH) (NCT07585721)
- Testing
- Calcium Hydroxide (Ca(OH)2), Bioceramic Intracanal Medicament
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Pulp Necrosis, Pulpitis
Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
Achieving effective root canal disinfection while minimizing postoperative pain is a critical goal in endodontic therapy. Advanced irrigation protocols, such as ultrasonic activation, laser activation, negative pressure…
- Trial name
- NCT07546773
- Testing
- Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Post Operative Pain Control, Endodontic Treatment
Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic…
- Trial name
- NCT06894069
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- University of Jordan
Asymptomatic Apical Periodontitis
Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment
This study aims to compare the effect of bio ceramic sealer and resin-based sealer on the intensity and occurrence of post operative pain in single rooted teeth with asymptomatic apical periodontitis.
- Trial name
- NCT06543004
- Testing
- AH plus sealer, Bioceramic sealer
- Where
- Qatar
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Primary Health Care Corporation, Qatar
Root Canal Therapy, Persistent Tooth Pain
DPBRN Persistent Pain and Root Canal Therapy
The purpose of this study is to document by survey the occurence of tooth pain present 3 months and 6 months after root canal therapy in the patients recruited for the DPBRN "Peri-operative tooth pain" study.
- Trial name
- NCT01201668
- Where
- 8 sites in United States, Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Pulp Necroses, Apical Periodontitis
"Postoperative Pain Following Laser-Assisted Root Canal Treatment: A Randomized Clinical Trial"
The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial.
- Conditions
- Pulp Necroses, Apical Periodontitis, Pulp Disease, Dental
- Trial name
- NCT06129643
- Testing
- Conventional group, Dual laser group, Combined group
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Irreversible Pulpitis With Apical Periodontitis
PRP Regenerative Endodontics vs. Root Canal Treatment for Post-Op Pain and Healing in Mature Teeth
This randomized clinical trial aims to compare the effectiveness of regenerative endodontic treatment using platelet-rich plasma (PRP) with conventional root canal treatment (RCT) in mature single-rooted teeth diagnosed with…
- Trial name
- NCT07124962
- Testing
- Root Canal Therapy, Platelet-Rich Plasma (PRP) Revascularization
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- HITEC-Institute of Medical Sciences
Diabetes Mellitus, Postoperative Pain After Endodontic Treatment
Postoperative Pain After Single vs Multiple-Visit Root Canal Treatment in Diabetic Patients
A short description of the clinical study, including a brief statement of the clinical study's hypothesis, written in language intended for the lay public.
- Trial name
- RCT-DM-Pain (NCT07271511)
- Testing
- Single-Visit Root Canal Therapy, Multiple-Visit Root Canal Therapy
- Volunteers
- 200 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Postoperative Pain After Endodontic Treatment, Direct Pulp Capping
Diagnostic Validity of a Quantitative Pulp Pain Scoring System and Its Association With Postoperative Clinical Outcomes
Pulpal diseases are among the most common reasons for endodontic treatment in dental practice. The dental pulp plays a critical role in maintaining tooth vitality, and its pathological changes directly affect pain perception and…
- Conditions
- Postoperative Pain After Endodontic Treatment, Direct Pulp Capping, Vital Pulp Therapy
- Trial name
- NCT07349511
- Testing
- Root canal treatment procedure based on the total score obtained from the Youden symptom scoring system, Vital pulp therapy procedure based on the total score obtained from the Youden symptom scoring system
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people
- Sponsor
- Recep Tayyip Erdogan University