Clinical trials: Post Operative Analgesia, active
Post Operative Analgesia
Intravenous Ibuprofen Postoperative Analgesia After Abdominal Hysterectomy
The current research is designed to investigate the analgesic efficacy of intravenous ibuprofen on the postoperative analgesic requirements, pain intensity and other recovery parameters.
- Trial name
- NCT05750264
- Testing
- Ibuprofen
- Where
- Egypt
- Volunteers
- 152 people
- Sponsor
- Menoufia University
Pain, Post Operative Analgesia
The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery
The goal of this single-center, pragmatic, randomized, blinded, placebo-controlled trial is to evaluate the impact of intravenous (IV) lidocaine within the existing Enhanced Recovery After Surgery (ERAS)program on outcomes in…
- Conditions
- Pain, Post Operative Analgesia, Opioid Consumption, Postoperative
- Trial name
- IMPALA ERAS (NCT07224711)
- Testing
- Lidocaine HCl 0.8% in D5W, Dextrose 5% in water
- Where
- United States
- Volunteers
- 2,290 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Acute Post-Operative, Dexmedetomidine
Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological Surgery
The aim of this study is to investigate and compare the effects of a continuous infusion of low-dose esmolol and dexmedetomidine versus placebo on intraoperative and postoperative opioid consumption and analgesic efficacy in…
- Conditions
- Pain, Acute Post-Operative, Dexmedetomidine, Analgesia, Esmolol
- Trial name
- NCT07846722
- Testing
- Esmolol hydrochloride, Dexmedetomidine, Normal (0.9%) saline
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Vasiliki Samartzi
Post Operative, Post Operative Analgesia
Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study
The goal of this clinical trial is to evaluate whether adding tizanidine to the standard postoperative pain regimen improves recovery after pelvic reconstructive surgery in adult women.
- Conditions
- Post Operative, Post Operative Analgesia, Urogynecologic Surgery
- Trial name
- TIPS (NCT07766837)
- Testing
- Tizanidine, Standard-of-Care Therapy
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Hartford Hospital
Pain, Postoperative, Post Operative Analgesia
Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy
The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST).
- Trial name
- NCT07507799
- Testing
- EXORA block 15, EXORA block 25
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Fayoum University Hospital
Post Operative Analgesia, Regional Anaesthesia
Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries
The overall goal of this work is to find the preferred continues catheter- based thoracic block for patients who undergoing major ROBOTIC assisted thoracic surgery (Lobectomy, multiple segmental resection and thoracotomy).
- Conditions
- Post Operative Analgesia, Regional Anaesthesia, Pain After Surgery, Opioid Consumption
- Trial name
- TPVB vs ESP (NCT07782073)
- Testing
- Paravertebral Nerve Block, ESP block group
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Analgesia, Pain Management
Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy
The aim of the study is to reduce postoperative pain by performing rectointercostal block in L/S cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.
- Conditions
- Analgesia, Pain Management, Pain, Acute Post-Operative
- Trial name
- NCT07745972
- Testing
- Rectointercostal facial plane block using bupivacaine 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Pain Management, TKA
Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study
A pilot study to assess the efficacy and feasibility of PBMT for pain control in patients undergoing a TKA and are discharged the same day from an ambulatory surgery center.
- Conditions
- Pain Management, TKA, Post Operative Analgesia, Low Level Laser Therapy
- Trial name
- NCT07750912
- Testing
- LightForce XLI
- Volunteers
- 15 people
- Sponsor
- Mohammad Burney, MD
Post Operative Pain, Analgesia
Evaluation of Postoperative Pain Control in Ear Surgery
Middle ear surgery is the most popular procedure in ear, nose and throat surgery. Increased sympathetic stimulation after surgery can activate the sympathetic system, causing hypertension and increased heart rate.
- Trial name
- NCT06869967
- Testing
- Auricularis Magnus Nerve Block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kocaeli University
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Post Operative Recovery, Post Operative Nausea and Vomiting (PONV)
A COMPARATIVE STUDY BETWEEN OPIOID-FREE GENERAL ANAESTHESIA AND OPIOID-BASED GENERAL ANAESTHESIA ON THE QUALITY OF RECOVERY IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC HYSTRECTOMY: A Randomized Trial
the intent of this study To compare the efficacy of opioid free general anaesthesia versus opioid based general anaesthesia to achieve enhanced recovery regarding post-operative pain and post-operative nausea and vomiting…
- Conditions
- Post Operative Recovery, Post Operative Nausea and Vomiting (PONV), Post Operative Analgesia
- Trial name
- NCT07739641
- Testing
- Fentanyl-Based Anesthesia, Opioid-Free Anaesthesia (Dexmedetomidine, Ketamine, and Lidocaine)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part B
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666009)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666971)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Post Operative Analgesia
Comparative Study Between Ultrasound Guided Paravertebral Plane Block and Erector Spinae Plane Block on Post-operative Analgesia After Total Abdominal Hysterectomy
The intent of this study is to compare the efficacy of the erector spinae plane block (ESPB) and paravertebral plane block in reducing postoperative opioid consumption and pain in patients with total abdominal hysterectomy.
- Trial name
- NCT07610070
- Testing
- Paravertebral Plane Block, Erector Spinea Plane Block, bupivicaine 0.25%
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Cesarean Birth, Post Operative Analgesia
The Effect of Lactoferrin on Pain Management Following Cesarean Section
This study evaluates whether lactoferrin, a naturally occurring protein with anti-inflammatory and antioxidant properties, can improve pain control after cesarean section.
- Trial name
- NCT07502235
- Testing
- Lactoferrin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Post Operative Analgesia
Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy
TAH, being a large scale gynaecological operation, is a construction bound to cause serious postoperative pain to the patient in that the procedure will inevitably entail massive tissue dissection.
- Trial name
- NCT07480499
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Post Operative Analgesia, Tonsillectomy With or Without Adenoidectomy
Preoperative High-Dose Oral Paracetamol for Postoperative Analgesia in Children Undergoing Tonsillectomy"
This randomized clinical trial compares two different preoperative doses of oral paracetamol (acetaminophen) in children undergoing elective tonsillectomy.
- Trial name
- NCT07463482
- Testing
- Paracetamol (acetaminophen)
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Thammasat University
Analgesia, Post Operative Pain
Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.
Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.
- Conditions
- Analgesia, Post Operative Pain, Acute Pain, Functional; Anesthesia
- Trial name
- EVN/EDAF (NCT07310953)
- Testing
- Group A: Rescue analgesia if NVS>4, Group B: Rescue analgesia if NVSm > 4 + FAS C
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Colorectal Cancer, Colorectal Surgery
Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP)
Effective postoperative pain management is essential for enhanced recovery after laparoscopic colorectal surgery. This randomized, controlled, double-blind trial will compare conventional postoperative analgesia (intravenous…
- Conditions
- Colorectal Cancer, Colorectal Surgery, Anesthesia, Autonomic Nerve Block
- Trial name
- BAPTAP (NCT07388953)
- Testing
- Minimally Invasive Left-Sided Colorectal Resection, BAPTAP (Peripheral Autonomic Blockade + TAP Block), Trocar/Incision Infiltration
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal