Clinical trials: Post Mastectomy
Breast Cancer
Use of Dermal Matrix in Breast Reconstruction
We propose to evaluate the question of whether there is a significant difference between the traditional method of serratus flap tissue expander reconstruction and the acellular matrix method.
- Trial name
- NCT00692692
- Testing
- DermaMatrix, standard of care tissue expander breast reconstruction surgery after mastectomy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University
Breast Implant; Complications, Breast Implant Protrusion
Standard Silicone-based vs. B-Lite® Light Weight Breast Implant After Total Mastectomy and Radiotherapy for Breast Cancer
Reconstructive surgery with breast implants after total mastectomy for breast cancer is invariably related to several possible complications, such as atrophy of surrounding tissues, skin thinning, capsular contracture, wound…
- Conditions
- Breast Implant; Complications, Breast Implant Protrusion, Breast Cancer, Radiotherapy Side Effect
- Trial name
- BLITE-01 (NCT03737500)
- Testing
- B-Lite® light weight breast implant, Standard silicone-based breast implant
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Lymphedema, Post Mastectomy
A Pilot Study Assessing the Effect of Lymphaticovenous Micro-Anastomosis in the Treatment of Postmastectomy Lymphedema
This study will assess the impact of lymphaticovenous microanastomosis in volume reduction of postmastectomy upper extremity lymphedema.
- Trial name
- NCT02020837
- Testing
- Lymphaticovenous Micro-Anastomosis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Arkansas
Neuropathic Pain Induced by Mastectomy
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on…
- Trial name
- NCT07475520
- Testing
- Lidocaine 2%, Lidocaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Mastectomy, Breast Reconstruction
Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction
Use of a HADM and implant in post-mastectomy breast reconstruction.
- Trial name
- NCT02263261
- Testing
- Flex HD Pliable Perforated HADM
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Musculoskeletal Transplant Foundation
Post Operative Pain, Quality of Recovery After Mastectomy
Quality of Recovery From Mastectomy With and Without PECS Blocks
This is a prospective observational study. Investigators want to understand post-operative recovery for patients undergoing mastectomy at NorthShore University HealthSystem.
- Trial name
- NCT05795413
- Testing
- Mastectomy with PECS blocks, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Breast Cancer, Post-mastectomy Pain Syndrome
Incidence and Factors Affecting the Development and Outcome of Post Mastectomy Pain Syndrome
This multi-centre, prospective study aims to obtain a precise estimate of the local incidence of PMPS and identify biopsychosocial risk factors contributing to the development of PMPS.
- Trial name
- PMPS (NCT04989179)
- Where
- 3 sites in Singapore
- Volunteers
- 220 people
- Sponsor
- Singapore General Hospital
Breast Cancer, Lymphocele
Efficacy Study of Ifabond in Breast Cancer Surgery
A randomized prospective simple-blind interventional study evaluating the efficacy of the synthetic adhesive solution "Ifabond", in patients undergoing breast cancer surgery.
- Trial name
- Ifabond (NCT01742975)
- Testing
- IFABOND (TM)
- Where
- 2 sites in France
- Volunteers
- 104 people
- Sponsor
- Hôpital Européen Marseille
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Chronic Pain
Physical Exercise, Motor Activity and Post-mastectomy Pain Syndrome.
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT05713786
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Breast Cancer
Multi-Beam Intensity-Modulated Radiation Therapy for Node-Positive Breast Cancer
This study is being performed to understand the safety of a new radiation treatment called "Multi-Beam Intensity Modulated Radiation Therapy" ( IMRT).
- Trial name
- NCT01127373
- Testing
- Multi-Beam Intensity-Modulated Radiation Therapy, BreastQ questionnaire-
- Where
- 7 sites in United States
- Volunteers
- 116 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mastectomy; Lymphedema
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy
Breast cancer is the most common type of cancer in women. Removal of the breast, called "mastectomy", is performed either when there is cancer-or an increased risk of cancer-in the breast.
- Trial name
- NCT05444361
- Testing
- Cryoneurolysis
- Where
- 5 sites in United States
- Volunteers
- 216 people
- Sponsor
- University of California, San Diego
Breastcancer
Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years
This study will evaluate the effect of highly accelerated external beam radiotherapy (EBRT) in 5 fractions over 10 days compared to 15 fractions over 3 weeks for early as well as locally-advanced stage breast cancer.
- Trial name
- HAI-5-III (NCT03121248)
- Testing
- WBI 5 fractions, WBI 15 fractions, LNI 5 fractions
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- University Hospital, Ghent
Breast Cancer
Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block
Modified radical mastectomy is the most commonly performed surgical approach for breast cancer. The procedure enables surgeons to remove the main tumor mass, adjacent glandular tissue and regional lymph nodes.
- Trial name
- NCT06300099
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Breast Cancer
Post Mastectomy Hypofractionated Radiotherapy in High Risk Breast Cancer
The purpose of this study is to compare the efficacy and toxicities of hypofractionated radiotherapy with conventional fractionated radiotherapy in high risk breast cancer patients treated with mastectomy.
- Trial name
- NCT03319069
- Testing
- Hypofractionated radiotherapy, Conventional fractionated radiotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahmed Ahm
Modified Radical Mastectomy
Effect of ERAS and Upper Limb Exercise on LoS After Modified Radical Mastectomy
The goal of this clinical trial is to learn if Enhanced Recovery After Surgery (ERAS) protocol and upper limb exercise shorten the length of stay (LoS) in adults after modified radical mastectomy (MRM) surgery.
- Trial name
- NCT07574372
- Testing
- Enhanced Recovery After Surgery, Upper Limb Exercise
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Prof. R. D. Kandou General Hospital
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period.
- Conditions
- Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
- Trial name
- NCT03656679
- Testing
- Pectoralis Blockade (PECs), Paravertebral Blockade
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Ventral Hernia, Post-mastectomy Breast Reconstruction
Analysis and Characterization of Biologic Implants
The purpose of this study is to investigate what happens to biologic mesh in the body over time on a molecular level. To date, it is not known what agents, enzymes, or proteins are interacting at the implantation site that…
- Trial name
- NCT01060046
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Washington University School of Medicine
Kinetic Control, Dysfunction
Effect of Kinetic Control Exercise on Shoulder Dysfunction Post Mastectomy
The purpose of this study is to evaluate the effect of kinetic control exercises on shoulder dysfunction in post-mastectomy.
- Conditions
- Kinetic Control, Dysfunction, Shoulder, Mastectomy
- Trial name
- NCT07023913
- Testing
- kinetic Control exercises, traditional treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Radiation Dermatitis, Skin Microbiome
The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients
The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find…
- Conditions
- Radiation Dermatitis, Skin Microbiome, Breast Cancer, Reconstructive Surgery
- Trial name
- NCT05032768
- Testing
- post-operative radiotherapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University