Clinical trials: Post Concussion Symptoms
Concussion Post Syndrome
The Effect of Binasal Occlusion on Balance Following a Concussion
This study evaluates the effect of binasal occlusion (BNO) glasses on balance and eye movement in adults with dizziness after a concussion.
- Trial name
- NCT03355339
- Testing
- Binasal occlusion, No binasal occlusion
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic
Effect of Mental Imagery in Patients With Persistent Post-concussion Symptoms
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic, Post Traumatic Headache
- Trial name
- NCT07166536
- Testing
- Provocation Test for Symptoms Using Mental Imagery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital
Concussion, Mild Traumatic Brain Injury
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion (Acute Phase)
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the acute period after concussion.
- Trial name
- Breathe - PED (NCT07572734)
- Testing
- Paced breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Concussion, Sport-Related Concussion
Trial Study of an Exercise Program for Youth With Persistent Symptoms After Concussion
The purpose of this randomized control trial study is to determine if an active rehabilitation (low intensity exercise program) in combination with a comprehensive education intervention (standard care) is more effective than the…
- Conditions
- Concussion, Sport-Related Concussion, Mild Traumatic Brain Injury
- Trial name
- NCT02257749
- Testing
- Active Rehabilitation, Comprehensive Education Intervention (Standard Care)
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Traumatic Brain Injury, Mild Traumatic Brain Injury
Effect of Graded Aerobic Exercise in Mild Traumatic Brain Injury
There is a paucity of knowledge about mechanisms behind mild traumatic brain injury (mTBI) subgroup's sustained problems, and effective interventions that can alleviate this disabling condition.
- Trial name
- NCT06177509
- Testing
- Graded Aerobic Exercise
- Where
- 2 sites in Norway
- Volunteers
- 72 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Post Concussion Syndrome
Effects of Osteopathic Treatment on Vestibular Disturbed Active Post Concussed Individual
The proposed study is a randomized clinical trial with the purpose of determining the efficacy of osteopathic treatment on vestibular symptoms of the post concussed vestibular disturbed athlete as determined by the Dizziness…
- Trial name
- PCS (NCT01962883)
- Testing
- Osteopathic treatment
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Collège d'Études Ostéopathiques
Concussion, Intermediate
Magnesium and Riboflavin Treatment for Post-Concussion Headache
This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion.
- Trial name
- NCT06260072
- Testing
- magnesium and riboflavin supplement
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Brain Injury, Chronic
Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on long-term symptoms after brain injury.
- Trial name
- HYBOBI2 (NCT01986205)
- Testing
- Hyperbaric Oxygen, Minimal pressure air
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Lindell Weaver
Vestibular Rehabilitation
Vestibular Rehabilitation Exercise in Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of long-term disability and mortality. The costs associated with hospitalization, rehabilitation, and productivity losses after injury impose a significant socioeconomic and…
- Trial name
- NCT06118541
- Testing
- Vestibular Rehabilitation therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Post Concussion Syndrome
GyroStim for Post Concussion Syndrome
The goal of this study is to evaluate the efficacy of using sensorimotor multi-axis automated rotational therapy (SMART) to help treat post concussion syndrome (PCS) in adults.
- Trial name
- NCT07527663
- Testing
- Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Neuroscience Group
Post-Concussion Syndrome, COVID Long-Haul
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Post Concussion symptoms.
- Conditions
- Post-Concussion Syndrome, COVID Long-Haul, COVID-19
- Trial name
- NCT04978571
- Testing
- percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Children's Hospital of Orange County
Mild Traumatic Brain Injury, Post-Concussive Symptoms
Consistency of Automated Neuropsychological Assessment Metrics (ANAM) Performance in Those With Deployment Acquired Mild Traumatic Brain Injury (TBI)
The purpose of this project is to explore the degree to which performance consistency on neuropsychological measures varies in a sample of Operation Iraqi Freedom (OIF)/Operation Enduring Freedom (OEF) Veterans with a history of…
- Trial name
- ANAM (NCT01334528)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Autonomic Nervous System Disease, Concussive Injury
Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms
Many combat veterans (c-Vs), service members (SMs) and civilians with mild traumatic brain injury (mTBI, also termed concussion) suffer from persistent post-concussion symptoms (PPCS) that degrade physical and cognitive…
- Conditions
- Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT07071350
- Testing
- HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Virginia Commonwealth University
Persisting Symptoms After Concussion
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
The goal of this randomized controlled trial is to evaluate the safety, feasibility, and efficacy of psilocybin assisted therapy as an intervention to reduce symptom burden in adult patients (aged 18-65) with persisting symptoms…
- Trial name
- PatACT (NCT06615908)
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Mild Traumatic Brain Injury, Concussion, Mild
Facilitating Access to Specialty Treatment
The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel mobile health intervention…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
- Trial name
- NCT05741411
- Testing
- RPM-assisted specialist access
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Children's Hospital of Philadelphia
Post-Concussion Syndrome
ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion
This is a Phase 1 Clinical Safety Study intended to provide preliminary assessments of the safety, tolerability, and clinical alleviation of symptoms associated with Post Concussion Syndrome (PCS), also known as Chronic…
- Trial name
- NCT04744051
- Testing
- 50 Adipose Derived Stem Cell Infusion, 150 Adipose Derived Stem Cell Infusion, 300 Adipose Derived Stem Cell Infusion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- American CryoStem Corporation
Posttraumatic Headache, Combat Disorders
Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin
The purpose of this study is to determine if prazosin is more effective than placebo in decreasing frequency, severity, disability, and other negative effects of headaches related to mild traumatic brain injury in Service Members…
- Conditions
- Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache
- Trial name
- NCT02266329
- Testing
- prazosin hydrochloride
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Headaches Posttraumatic
SMART Concussion Trial: Symptom Management vs Alternative Randomized Treatment of Concussion Trial
Given the rising rates of concussion in youth ages 10-19 and the significant proportion of young people who remain symptomatic for months following concussion, research evaluating the efficacy of multifaceted treatment options…
- Conditions
- Mild Traumatic Brain Injury, Headaches Posttraumatic, Neck Pain, Dizziness
- Trial name
- SMART (NCT05446597)
- Testing
- Symptom-specific Headache Treatment, Symptom-specific Dizziness &/or Neck Pain Treatment, Multimodal Concussion Treatment
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of Calgary
Traumatic Brain Injury, Post-concussive Headaches
Strength and Awareness in Action: an Intervention for Post-Acute TBI Headaches (SAA-TBI)
The specific aims of the proposed study are to evaluate: 1) the feasibility of design elements of a Strength and Awareness in Action: an Intervention for Post-Acute TBI Headaches (SAA-TBI) intervention trial (e.g., an exercise…
- Trial name
- SAA-TBI (NCT03277859)
- Testing
- SAA-TBI
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Eastern Colorado Health Care System