Clinical trials: Post Cardiac Surgery
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Post-Cardiac Surgery Patients
Comparative Effects of Buteyko Exercise and Corpse-Pose Technique on Cardiac Surgery Patients
Open-heart surgeries such as coronary artery bypass grafting and valve replacements have been used to improve patient outcomes related to cardiac symptoms, prolongation of life, and health-related quality of life.
- Trial name
- NCT05425095
- Testing
- Buteyko Breathing Technique, Corpse-Pose Technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Ischemic Heart Disease
Optimum Platelet Inhibition After Coronary Bypass Surgery
To investigate the effect of different dosages of aspirin on platelet aggregation and to determine the possible mechanisms of aspirin resistance, we intend to compare the effects of low, medium dose aspirin with clopidogrel (an…
- Trial name
- NCT00262275
- Testing
- Aspirin, Clopidogrel
- Where
- United Kingdom
- Sponsor
- Papworth Hospital NHS Foundation Trust
Anxiety, Discharge Readiness
The Effect of Nurse-led Video-assisted Discharge Training on Anxiety and Readiness for Discharge After Coronary Artery Bypass Graft Surgery
This clinical trial aims to evaluate the effect of nurse-led video-assisted discharge education on discharge readiness and anxiety in patients undergoing coronary artery bypass graft surgery.
- Conditions
- Anxiety, Discharge Readiness, Nursing, Training
- Trial name
- NCT06806631
- Testing
- Video assisted discharge training
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Uskudar University
Post-operative Atrial Fibrillation, CABG
Empagliflozin to Prevent Post-Operative Atrial Fibrillation
This is an interventional, double-blind, placebo controlled, multicenter, randomized clinical trial with allocation sequence concealment and blinded endpoint adjudication.
- Trial name
- EMPOAF (NCT06124937)
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Iran
- Volunteers
- 492 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Bariatric Surgery, Cardiac Surgery With Sternotomy
Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery
This is prospective, randomized study. The purpose of this study is to evaluate whether the addition of Suzetrigine to well established multimodal pain regimen for participants undergoing bariatric patients undergoing weight-loss…
- Conditions
- Bariatric Surgery, Cardiac Surgery With Sternotomy, Post-operative Pain
- Trial name
- SMOOTH-SURG (NCT07539623)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Transposition of Great Vessels, Outcome, Fatal
Outcomes of Transposition of the Great Arteries After Arterial Switch Operation
Transposition of the great arteries (TGA) is a complex cyanotic congenital heart disease and patients suffer from a high mortality rate within one year of age without appropriate management.
- Trial name
- NCT05089773
- Testing
- The arterial switch operation
- Where
- 2 sites in China
- Volunteers
- 1,281 people
- Sponsor
- Children's Hospital of Fudan University
Cardiac On-pump Surgery
Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass
Organ protection, volatile anesthetics, postconditioning. Sedation of patients on ICU after cardiac surgery with cardiopulmonary bypass with either propofol or sevoflurane.
- Trial name
- NCT00924222
- Testing
- Sevoflurane, Propofol
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Kidney Failure, Acute
Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy
The purpose of this study is to determine whether sodium bicarbonate is effective in reducing kidney injury that may occur during cardiac surgery.
- Trial name
- PARACHUTE (NCT00522756)
- Testing
- Sodium bicarbonate, Sodium chloride
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Transesophageal Echocardiography, Vena Cava Superior
Respiratory Variations of the Diameter of Superior Vena Cava for Predicting Fluid Responsiveness After Cardiac Surgery
In a recent study (Vignon 2017), respiratory variations of the diameter of superior vena cava had a greater diagnostic accuracy than pulse pressure variations and inferior vena cava respiratory variations in 540 medical and…
- Trial name
- NCT03393897
- Testing
- Trans oesophageal echocardiography, Trendelenburg test
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Graft Patency, Coronary Artery Bypass Grafting Surgery
ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine whether adding clopidogrel to aspirin after coronary bypass operation (CABG) improves graft patency, in patients that have preoperatively increased platelet activity(hypercoagulable) and…
- Conditions
- Graft Patency, Coronary Artery Bypass Grafting Surgery, Hypercoagulability, Thrombosis
- Trial name
- TEG-CABG (NCT01046942)
- Testing
- Clopidogrel+acetylsalicylic acid, acetylsalicylic acid
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Kidney Injury
An Observational Case Control Study to Identify the Role of MV and MV Derived Micro-RNA in Post CArdiac Surgery AKI
Acute kidney injury (AKI) complicates over 25% of cardiac surgical procedures where it increases mortality up to fourfold. The incidence of AKI is increasing, the pathogenesis is poorly understood, current diagnostic tests lack…
- Trial name
- MaRACAS (NCT02315183)
- Testing
- This is an observational Study
- Where
- United Kingdom
- Volunteers
- 96 people
- Sponsor
- University of Leicester
Acute Lung Injury, Metabolic Disturbances
Acute Lung Injury After Cardiac Surgery: Pathogenesis
The purpose of the present study is to visualize the inflammatory response and coagulation disorders during cardiac surgery in order to identify possible predictors for acute lung injury postoperatively.
- Conditions
- Acute Lung Injury, Metabolic Disturbances, Inflammation, Coagulation; Intravascular
- Trial name
- ALI (NCT02475694)
- Testing
- No intervention
- Volunteers
- 50 people
- Sponsor
- Aalborg University Hospital
Low Cardiac Output Syndrome After Adult Cardiac Surgery
Peak Systolic Global Longitudinal Strain and Low Cardiac Output Syndrome After Cardiac Surgery
This is a retrospective observational study to assess the relationship between peak systolic global longitudinal strain measured on pre-cardiopulmonary bypass trans-esophageal echo images predicts post-operative low cardiac…
- Trial name
- NCT02771080
- Testing
- Cardiac surgery
- Volunteers
- 275 people
- Sponsor
- University of Liege
Surgery
Natriuretic Peptides - Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?
The investigators hypothesize that the level of perioperative natriuretic peptides is associated with in-hospital and long term major adverse cardiac events.
- Trial name
- NCT00942786
- Where
- Austria
- Volunteers
- 297 people
- Sponsor
- Medical University of Graz
Congenital Heart Disease in Children
How to Report Postoperative Outcomes After a Paediatric Cardiac Surgery ?
Congenital heart disease is a common abnormality in newborns. The marked improvement in the surgical management of congenital heart disease has led to a reduction in postoperative mortality, historically a quality criterion for…
- Trial name
- Pedia-Card (NCT05546983)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Strasbourg, France
Hemostasis
In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB)
This primary aim of this study is to compare the in vivo effects of fibrinogen concentrate and cryoprecipitate on the neonatal fibrin network after surgery with cardiopulmonary bypass to develop effective and safe strategies for…
- Trial name
- NCT03932240
- Testing
- Fibrinogen Concentrate (FC), Cryoprecipitate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Emory University
Cardiac Surgery Associated Acute Kidney Injury
Serum and Urine Metabolome Studies in Patients With Acute Kidney Injury After Cardiac Surgery
The goal of this observational study is to learn about serum and urine metabolome in patients after cardiac surgery.
- Trial name
- NCT06245720
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Health Status, Anxiety
Effect of Cardiac Rehabilitation on Health Status, Emotional Outcomes, and 90-day Readmission Rate Among Cardiac Surgery Patients
this study aims to investigate the effect of the cardiac rehabilitation program on perceived health, status, anxiety, depression, and 90-day readmission rates for post-cardiac surgery patients.
- Conditions
- Health Status, Anxiety, Depression, 90-day Readmission
- Trial name
- NCT06118918
- Testing
- Phase II comprehensive cardiac rehabilitation program
- Where
- Jordan
- Volunteers
- 122 people
- Sponsor
- Universiti Putra Malaysia
Opioid Use, Heart; Surgery, Heart, Functional Disturbance as Result
Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial
This study will compare an opioid free anesthetic, using dexmedetomidine, to a traditional opioid based anesthetic, using fentanyl, for patients undergoing cardiac surgery with regards to hemodynamic stability in the first 10…
- Conditions
- Opioid Use, Heart; Surgery, Heart, Functional Disturbance as Result, Anesthesia
- Trial name
- NCT04197570
- Testing
- Opioid Anesthetics, Non Opioid Analgesics
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Benaroya Research Institute